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萘醌

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In order to study the struture activity relationship of these naphthazarin compounds and to search for more effective anti-tumor agents. We synthesized dl-shikonin and shikonin, alkannin respectively.

为了对这类萘醌类化合物作进一步的抗肿瘤活性试验,我们合成了消旋紫草素,紫草素,异紫草素及环紫草素和环异紫草素,并探讨其可能的作用机制,和作用区域。

Synthesis of β-methylnaphthoquinone without any catalyst in the CH_3COOH-H_2O_2 system by oxidation of β-methylnaphthalene is researched. We have discussed the feasibility of the technology.

在不添加任何催化剂的条件下,以冰醋酸为溶剂,用过氧化氢氧化β-甲基萘制取β-甲基萘醌

The result indicates that the naphthalin ring in Naphthol green B molecule is degraded as organic acid and benzoquinone, and further becomes inorganic substances by chlorine dioxide direct oxidation and catalytic oxidation so that the ability to biology treatment of the difficulty degradation wastewater is improved, which is good for the further treatment.

结果表明,萘酚绿经化学氧化和催化氧化后,分子中萘环被氧化降解为羧酸和萘醌,并进一步降解为无机物,提高了废水的可生化性,为难降解废水的后续处理创造了条件。

The type and position of substituents affected OWF〓 greatly for naphthoquinone and anthraquinone derivatives.

4取代基类型和取代基位置对OWF〓有较大的影响,如萘醌类发色母体、蒽醌类发色母体等。

Objective To explore the cytotoxicity on eight kinds of human cancer cell lines and apoptosis induction on human nasopharyngeal cancer cells(CNE_2) of a new semi-synthesized naphthoquinone derivative(2,3,11-triethanesulfanyl-6-isohexenylnaphthazarin,TEISHNZ).

目的探讨一种新的人工半合成紫草萘醌类衍生物(2,3,11-三乙巯基-6-异己萘茜,简称TE ISHNZ)。

This paper intends to report three experimentally simple preparations of naphthoquinone, hydroquinone and the corresponding mixed quinhydrone ,all redox chemistry being carried out in the solid state.

报导了通过固体氧化还原作用以制取α-萘醌,氢醌以及对应的醌氢醌试剂,所有反应均在固体状态下进行

By the chemical composition of carotenoids can be divided into categories, anthraquinone, naphthoquinone type, type of flavonoid, curcumin category, indigo type, chlorophyll a total of seven kinds of categories.

按化学组成可分为胡萝卜素类、蒽醌类、萘醌类、类黄酮类、姜黄素类、靛蓝类、叶绿素类共7种。

Reactions of 2-methyl-1,4 naphthoquinone with human telomeric DNA and telomerase RNA ESR spin elimination has been used with 4-oxo-TEMPO as spin trap. The reactivities of 3VK3* with telomeric DNA, template of telomerase RNA and its L6-P6 region have been confirmed respectively. The results show that the reactivity of 3VK3* with polynucleotides is directly proportional to their G amount, and the one for reaction of 3VK3* with telomeric DNA is the highest in polynucleotides. 2. Reactions of 2-methyl-1,4 naphthoquinone with nucleosides, nucleotides ESR spin elimination has been used with 4-oxo-TEMPO as spin trap.

2-甲基-1,4萘醌与端粒DNA及端粒酶RNA亚基光敏反应性的研究应用ESR自旋消减法,对2-甲基-1,4萘醌(VK3)与端粒DNA重复序列、端粒酶RNA亚基模版序列、端粒酶RNA亚基L6-P6发夹区关键序列的光敏反应性进行了研究,结果表明,在一定波长照射下,明显诱导VK3与上述寡聚核苷酸反应,其反应性大小与核酸中鸟嘌呤含量正相关,其中端粒DNA序列反应性最强。

The present doctoral dissertation was carried out to study the chemical constituents isolated from stems of two medicinal schisandraceous plants.34 compounds were isolated from the ethanol extracts of the stems S.henryi collected in the Jiangxi province by various column chromatographies.27 of them were identified on the basis of spectral analysis.There are 18 lignans,(including 5 dibenzocyclooctadienes,6 aryltetralins,2 tetrahydrofurans,3 diarylbutanes,2 other lignans),3 flavanols,2 glyceroesters,1 naphthoquinone,1 xanthine and 2 steroids,of which 6 compounds were new compounds,and 7 compounds were isolated from this family for the first time.

采用多种色谱技术进行分离纯化,从翼梗五味子藤茎的乙醇提取物中分离到34个化合物,综合运用现代波谱学技术鉴定了27个化合物,包括木脂素类化合物18个(其中联苯环辛烯类木脂素5个,芳基四氢萘类木脂素6个,四氢呋喃类木脂素2个,二芳基丁烷类3个,其他类型木脂素2个),黄烷醇类化合物3个,甘油酯类化合物2个,萘醌类化合物1个,黄嘌呤类化合物1个,甾体类化合物2个,其中,5个为新化合物,7个为本科首次报道。

Chloro-5,12-naphthacenequinone was synthesized from 2-(1-hydroxy-2-naphthyl)carbonylbenzoic acid by chlorination reaction using a mixture of phosphorus pentachloride and phosphorus oxychloride as a chlorating agent and then by ring-closing reaction using sulfuric acid as a dehydrating agent.

以2-[(1-羟基-2-萘基)羰基]苯甲酸为原料、五氯化磷/三氯氧磷为氯化剂进行氯化反应,然后用浓硫酸脱水环化,合成了6-氯-5,12-萘并萘醌,优化了反应条件,总收率达68.2%。

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