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A better understanding of the role of PPAR in insulin action system will be critical in developing more efficacious and safe agent s that act on PPAR and benefit patients with type 2 diabetes. The main content is followed: Synthesis and analysis of 1,3-dicarbonyl compounds. Make use of easily available cheap reagent such as 2-naphthol, 6-hydroxyquinoline, 1,2-dibromoethane, 4- hydroxybenzaldehyde, dimethyl malonate, 2-{4- [(2-napthoxy)ethoxyl] benzyl} malonates and 2-{4 [(1,2,3,4-tetrahydro-6 -quinolinoxy)ethoxyl] benzyl } malonates were synthesized through 6-8 steps in virtue of Williamson, Knoevenagel reaction, Pd/C catalyzed hydrogenation with mild conditions and high yield. The total yield of 40-50%.

本论文的主要内容和研究结果如下: 1,3-二羰基类化合物的合成及分析,采用2-萘酚、6-羟基喹啉、1 ,2二溴乙烷、对羟基苯甲醛、丙二酸二甲酯等常见易得试剂,利用Williamson反应、Knoevenagel反应、钯碳加氢等条件温和且收率高的方法,分别合成了2-{4- [(2-萘氧)乙氧基]苄基}丙二酸衍生物和2-{4 [(1,2,3,4-四氢-6-喹啉氧基)乙氧基]苄基}丙二酸衍生物两个系列8个化合物,经6-8步反应,总收率为40-50%,具有一定绿色化学特性。

Naphthol ethyl ether was sythesized with the ethanol and β-naphthol as materials and aluminium sulfate as catalyst.

介绍了以乙醇和β-萘酚为原料,在硫酸铝Al2(SO43.18H2O催化下合成β-萘乙醚的方法,讨论了反应时间,催化剂用量以及反应物摩尔比对合成的影响,确定了最佳反应条件。

A new method for directly producing naphthol from naphthalene is studied in this paper,in which spinel-type magnesium ferrite is used as the catalyst and hydrogen peroxide as the oxidant.

研究了萘一步催化氧化合成萘酚的新方法,该法以具有尖晶石结构的铁酸镁为催化剂,过氧化氢为氧化剂。

Naphthyl aceate was synthesized with acetic anhydride and naphthol using aminosulfonic acid as catalyst.

以氨基磺酸为催化剂,用乙酸酐和β-萘酚合成了乙酸β萘酯。

N-Methyl-3,3-dimethyl spiroindoline-2,3'[3H] naphthaline [2,1-b] [1,4] oxazine was synthesized by 1,3,3-trimethyl-2-methylene indoline and 1-nitroso-2-naphthol, its UV and IR spectra and elemental analysis were carried out, and the photochromism and main influencing factors such as temperature, solvent and pH were studied.

以1,3,3-三甲基-2-亚甲基吲哚啉和1-亚硝基-2-萘酚为原料合成了N-甲基-3,3-二甲基螺吲哚啉-2,3'[3H]萘并[2,1-b][1,4]恶嗪,对其进行了紫外和红外光谱以及元素分析,并对其光致变色性质以及主要影响因素温度、溶剂和pH进行了研究。

Biphenol (8), binaphthol monomethyl ether (9) or 2, 2'-diamino-1, 1'-binaphthalene (10) remained inert in the same condition.

而联苯酚(8)、联萘酚单甲醚(9)和联萘胺(10)在同样条件下不发生反应。

Naphthoxyacetic acid was synthesized from 2-naphthol , sodium hydroxide and chloroacetic acid under the microwave radiation.

在微波辐射下,以2-萘酚、氢氧化钠和氯乙酸为原料合成了2-萘氧乙酸。

This paper reported the synthesis of 2-hydroxyl-1-naphthalene formaldehyde under microwave irradiation with 2-naphthol, hexamethylenamine, solvent of glacial acetic acide, catalysis of sulphuric acid, and discussed the influence of the time and the power of microwave radiation, the proportion and quantity of reagents to the synthetic yield.

利用微波技术,采用2-萘酚与六次甲基四胺为原料,冰乙酸作溶剂,在浓硫酸的催化下合成2-羟基-1-萘甲醛,并考察了微波作用的时间、微波辐射功率、反应试剂的组成与用量等因素对产物产率的影响。

We have presented a practical method for the preparation of propargylic alcohols from terminal alkynes and carbonyl compounds promoted by KOH in the presence of 18-crown-6,and subsequent efficient cyclizations of propargylic alcohols with 2-naphthol catalyzed by InCl_3·4H_2O under the solvent-free ball-milling conditions.Ball milling exhibits its superiority over the reported methods in the preparation of propargylic alcohols and naphthopyran derivatives.

采用机械研磨方法进行了连续的两步固相化学反应的研究:首先,在氢氧化钾和18-冠-6的作用下,端基炔和羰基化合物在机械研磨条件下反应可以高效地生成相应的炔醇化合物;其次,在四水合三氯化铟的催化作用下,生成的炔醇化合物和2-萘酚在机械研磨条件下环加成生成相应的萘并吡喃产物。

This thesis consists of two main parts. Part one (chapter 1~4) is about the coppermediated biomimetic oxidation of naphthols and 2-naphthylamine.

本文包括两部分内容:第一部分(1~4章)为萘酚类和2-萘胺化合物在含铜化合物作用下的仿生氧化偶合反应研究。

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