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In many cases, ephrins act as negative regulators that stimulate growth cone collapse and inhibit neurite outgrowth.

在许多例子中,ephrin对於神经的发育扮演著负向的调控者,它们能够刺激神经生长锥的萎缩而抑制神经纤维的生长。

Alzheimer disease: A primary degenerative cerebral disease of unknown etiology with characteristic neuropathologcal and neurochemical features, including cortical atrophy with neurofibrillary tangles and neuritic argentophilic plaques, and a marked reduction on the enzyme choline acetyltransferase, in acetylcholine itself, and in other neurotransmitters and neuromodulators.

阿尔茨海默病:一种病因未明的原发退行性大脑疾病,具有特征性的神经病理和神经生化改变,包括伴有神经原纤维缠结和神经炎性嗜银斑的皮层萎缩,胆碱乙酰转移酶、乙酰胆碱本身、以及其它神经递质和神经调质的明显减少。

Results NR4A1 was mainly expressed in the cytosol of ova...

核受体NR4A1蛋白的表达与卵泡的发育成熟及黄体的萎缩有明显的相关性。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性(过度刺激神经元上的递质受体)、钙紊乱、炎症、能量和生长因子缺乏作用下,敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关,还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用,影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后,易感神经元会萎缩直至死亡,原因可能有兴奋性中毒(神经递质对神经元表面受体的过度刺激引起),钙稳态失衡,炎症反应,能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合,可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应,也可调节不同信号级联反应,这些级联反应对于维持神经元活动性和生存性意义重大。

The prevalency of wasteful vogue and the expansion of extravagant consume, not only made the social production stagnate and shrink, but also made the handicraft industry and commerce develop abnormally, as a result, affected the social economy of the time badly.

由于奢靡之风的盛行和奢侈消费的膨胀,不仅造成了社会生产的萎缩和停滞,而且也促使工商业畸形发展,从而对当时的社会经济产生了严重影响。

The physical symptoms of death, other than decomposition, set in (the onset and passing of rigor mortis, the receding of the gums and the skin of the scalp and fingertips, the pooling of blood at the bottom of the body).

那些自然的死亡症状,除了腐烂,开始(那开始和短暂的尸僵,那齿龈、头皮以及指尖的萎缩,血液淤积在身体的底部)。

It's unbelievable that Vista system itself unable to keep consistent usage rate of disk space and keep shrinking available amount of free space.

它的令人难以置信的说, Vista系统本身无法保持一致的使用率,磁盘空间和不断萎缩,可用的可用空间量。

The results show that:(1) wetland reservoirs can control wetland degeneration and springwater overflow;(2)wetland reservoirs can store floodwater and winter to prevent flood, drought and desertification so that keep ecological system balance of wetland;(3) uncoordinated contradiction between agricultural water use and ecological water demand can be resolved under the adjustable function of wetland reservoirs;(4)wetland reservoirs has effective capability to keep biological diversity.

对位于玛纳斯河流域泉水溢出带中的湿地水库群对流域生态环境的作用进行了研究,结果表明,该湿地水库群在防止湿地萎缩退化、防止次生盐渍化、保护流域内生物多样性、防风固沙、防止土壤沙化、抵御洪、旱灾害威胁、加强湿地调控能力以及增加了绿洲的人口承载能力和生产力等方面起到了很好的保护作用。

Jing Linbo expresses when accepting our newspaper reporter to interview, the influence of global banking crisis is in gradually outspread, direct from exit model the enterprise begins to affect industry the enterprise of medium, upper reaches, Overseas order for goods cancels, the product sells market atrophy, often create company product keep long in stock, slow-moving, swap looks this kind was like primitive means to rise to help an enterprise alleviate in this special period the action of pressure.

中国社会科学院财贸研究所所长助理荆林波博士在接受本报记者采访时表示,全球金融危机的影响在逐渐延伸,从出口导向型企业开始波及到产业中、上游的企业,"海外订单取消,产品销售市场萎缩,往往造成企业产品积压、滞销,以货易货这种看似原始的方式在这个特殊时期起到了帮助企业缓解压力的作用。"

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力