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Ethnic Composition: Russian 85%, Tatar 3.9%, Ukrainian 2.4%, Chuvash 1.2%, Bashkir 1.0%,Belorussian 0.7%, Mordovian 0.7%, German 0.6%, Jews and others 4.5%.

民 族:85%俄罗斯人,3.9%鞑靼人,2.4%乌克兰人,1.2%楚瓦什人,1.0%巴什基尔人,0.7%白俄罗斯人,0.7%莫尔多瓦人,0.6%德意志人,4.5%犹太人和其他民族

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞,导致细胞生长的抑制和凋亡罗伯托利,斯特凡Purgato ,苏埃洛卡默琳,拉菲尔Fronza ,梅奥尼博洛尼亚,西蒙娜Alboresi ,莫妮卡弗兰索尼,罗伯托Corradini ,斯特凡诺斯福尔扎,安德烈Faccini ,杰森先生Shohet , Rosangela Marchelli ,和安德烈Pession儿科,博洛尼亚大学,圣' Orsola -马尔皮基医院,博洛尼亚,意大利;有机部和工业大学化学帕尔马,帕尔马,意大利和3Center的细胞和基因治疗,德州儿童癌症中心, Baylor医学院,得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞,针对一个独特的序列反义DNA链的第2外显子,并与在MYCN 其氨基端为核定位信号肽。

There was me and my monkey And with his dungarees and roller blades Smoking filter tips Reclining in the passenger seat of my super charged jet black Chevrolet He had the soft top down He liked the wind in his face He said son you ever been to Vegas I said no He said that's where we're gonna go You need a change of pace And when we hit the strip with all the wedding chapels and the neon signs He said left my wallet in El Segondo and proceeded to take two grand of mine We make tracks to the Mandalay Bay Hotel Asked the bell boy if he take me and my monkey as well He looked in the passenger seat of my car And with a smile he said If your monkey's got that kind of money sir Then we've got a monkey bed Me and my monkey With a dream and a gun I'm hoping my monkey don't point that gun at anyone Me and my monkey Like butch and the sundance kid Trying to understand why he did what he did Why he did what he did We got the elevator, I hit the 33rd floor We had a room up top with the paronama views like nothing you'd ever seen before He went to sleep in the bidest And when he awoke He ran his little monkey fingers through yellow pages Called up some escort services and ordered some okey doke Forty minutes later there came a knock at the door In walked this big bad ass baboom into my bedroom with three monkey whores Hi, my name is Sunshine, these are my girls Lace my palm with silver baby and oh yeah They'll rock your world So I watched pay per view and polished my shoes and my gun Was diggin' on Kurt Cobain singing about lithium There came a knock at the door and in walked Sunshine What's up you'd better get your ass in here boy Your monkey's having too much of a good time Got tickets to see Sheena Easton The monkey was high Said it was a burning ambition to see her before he died We left before encores he couldn't sit still Sheena was a blast baby but my monkey was ill We went to play blackjack kept hitting twenty three Couldn't help but notice this Mexican just staring at me Or was it my monkey I couldn't be sure It's not like you'd never seen a monkey in rollerblades and dungarees before Now don't test my patience cause we're not about to run That's a bad ass monkey boy and he's packing a gun My name is Rodrigue he says with death in his eye I've been chasing you for long time amigos And now your monkey's gonna die Me and my monkey Drove in search of the sun Now me and my monkey We don't wanna kill no Mexican But we've got Ten itchy fingers one thing to declare When the monkey is high You do not stare you do not stare You do not stare Looks like we've got ourselves a Mexican stand off here boy And I ain't about to run Put your gun down boy How'd I get mixed up with this fuckin' monkey anyhow

有我和我的猴子并且与他的dungarees 和路辗刀片抽烟过滤器要诀斜倚在我的超级被充电的喷气机黑色薛佛列汽车乘客座位他下来有软的上面他喜欢风在他的面孔他说您曾经是到维加斯I 说没有的儿子他说we're 去去的that's 您需要步幅的变动并且当我们击中了小条以所有婚礼教堂和霓虹灯广告他左说我的钱包在El Segondo 和进行采取二盛大我的我们做轨道对曼德勒海湾旅馆问响铃男孩如果他采取我并且我的猴子他看了在我的汽车乘客座位并且以微笑他说如果您的monkey's 得到了那金钱先生然后we've 得到了猴子床我和我的猴子与梦想和枪 I'm 希望我的猴子don't 把那杆枪指向任何人我和我的猴子象butch 和sundance 孩子设法了解为什么他做了什么他为什么他做了什么他我们得到了电梯,我击中了第33 楼我们有一间屋子上面以paronama 看法象没什么you'd 以前曾经被看见他去睡觉在bidest 并且当他醒了他跑了他小的猴子手指通过黄页召集了一些伴游服务和定购了一些okey doke 那里四十分钟以后来了敲在门在走了这大坏驴子baboom 入我的卧室与三个猴子妓女喂,我的名字是阳光,这些是我的女孩系带我的棕榈与银色婴孩和oh 呀 They'll 岩石您的世界如此我观看了薪水每看法和擦亮了我的鞋子和我的枪是diggin'在Kurt Cobain 唱歌关于锂那里来了敲在门和在走的阳光里 What's you'd 更好得到您的驴子在这里男孩您的monkey's 有太多好时光被得到的票看见Sheena Easton 猴子是高的前述这是灼烧的志向看见她在他死了之前我们离开在他couldn't 坐直的encores 之前 Sheena 是疾风婴孩但我的猴子是不适我们去演奏大酒杯继续击中二十三 Couldn't 帮助但注意这墨西哥人凝望我或是它I couldn't 是肯定的我的猴子 It's 不是喜欢you'd 以前从未被看见一只猴子在rollerblades 和dungarees 现在don't 测试我的耐心起因we're 不跑 That's 坏驴子猴子男孩和he's 包装枪我的名字是他说以死亡在他的眼睛的Rodrigue I've 追逐您为久时间朋友并且现在您的monkey's 去死我和我的猴子驾驶了寻找太阳现在我和我的猴子我们don't 不想要杀害墨西哥人但we've 得到了十个痒的手指一件事宣称当猴子是高的您不凝望您不凝望您不凝望看起来象we've 这里得到了墨西哥立场男孩并且I ain't 跑把您的枪男孩放下 How'd I 得到与这fuckin'混合;猴子无论如何或有我和我的猴与他dungarees和滚刀片吸烟过滤嘴斜倚在客运座位我国超级控喷射黑色雪佛兰他有软顶下来,他最喜欢的风在他的面对他的儿子说:你到过赌城我说没有,他说哪里,我们gonna你走需要改变步伐,而当我们打带所有的教堂婚礼和霓虹灯他说离开我的钱包在El segondo进而采取两项盛大的矿井,使我们路轨次电子曼德勒湾酒店询问钟男孩,如果他把我和我的猴子以及他的表情,在次电子乘客座位上我的车,面带微笑,他说,如果你的猴得到这笔钱思住宅,然后我们拿到猴床上,我和我的猴同一个梦想和一支枪,我希望我的莫 nkey不点炮人,在我和我的猴像布奇和森丹斯孩子设法了解后WH y他做他为何他做了什么,我们得到了电梯,我打到33楼,我们有一个房间顶与paronama看法没有像您见过会捶他睡在bidest而当他醒来,他跑他的小猴子手指透过黄坝天麻打电话询问过保姆服务,并订购了一些东西doke四十分钟左右,有一个前来敲门做或者走这个大坏驴子baboom到我的卧室有三名妓女猴喜,我的名字是阳光,硒是我的女孩花边我的手心与银宝宝,哦噢人家,你的摇滚世界,让我眼睁睁看着付每意见,并擦拭鞋子,我的枪是diggin '库尔特罗克塞特歌唱锂出现了一针玉在门口,并走在阳光下是怎么回事,你最好明白你的驴子在这里你男童和尚安永的有太大的一个好时机得到入场券见sheena伊斯顿猴高表示,这是燃烧的雄心,看到她生前我们离开之前,以encores他不能坐视sheena仍然是一个基本法 AST的婴儿,但我的猴子生病,我们去发挥酒杯一直打到23不禁通知书策墨这只是瞪着我,抑或是我的猴子,我也不能肯定它不像您在Neve 住宅看到一只猴子在晒太阳和dungarees之前,现在不考验我的耐心,我们的事业不是对办好次下午的一个坏驴子猴男孩和他的包装带枪我的名字是罗德里格说,他的死亡与他眼睛,我一直追你很久地球,现在你的猴死gonna我和我的博士猴脏器寻找太阳,现在我和我的猴子,我们不想杀任何墨西哥,但我们拿到碲氮手指发痒一回事申报时,猴子是高你不盯着你不盯哟美国不瞪眼样子,我们拿到了自己的立场,墨西哥产的男孩在这里,我并不是对办好把你的枪下男孩,我为什么会有这种攻防得到混为一谈这fuckin '猴不管怎样

As Rendel Harris says in "The Expositor"(1898), 174, Paul may have sent another letter from Athens by Timothy to the Thessalonians.

作为宏道哈里斯说在" Expositor "( 1898 ), 174 ,保罗可能发出另一封信来自雅典的蒂莫的撒罗。

Just as every English school child knows Rowena, Rebecca, Ivanhoe, and Sir Brian de Bois Guilbert, so every French reader knows the poor but beautiful gypsy Esmeralda with her little goat; the alchemist-priest Claude Frollo, who desires her; and Quasimodo, the "hunchback of Notre Dame," who loves her and tries to save her.

正如每个英国小学生了解罗维娜,丽贝卡,艾凡赫和布莱恩爵士一样,每个法国读者都知道穷困潦倒却貌美如花的吉普赛女郎艾斯梅拉达和她的小羊,渴望得到她的炼金牧师克劳德·弗罗洛,以及喜欢她并尽力营救她的巴黎圣母院驼背,加西莫多。

Famous authors include Loriot, Semp , Paul Flora, F.

他们旗下的著名作者包括罗里欧、桑贝、保罗·弗罗拉、魏西特、汉斯·塔思乐、汤米·温格尔和莫里斯?

We're here to memorialize 29 Americans: Carl Acord. Jason Atkins. Christopher Bell. Gregory Steven Brock. Kenneth Allan Chapman. Robert Clark. Charles Timothy Davis. Cory Davis. Michael Lee Elswick. William I. Griffith. Steven Harrah. Edward Dean Jones. Richard K. Lane. William Roosevelt Lynch. Nicholas Darrell McCroskey. Joe Marcum. Ronald Lee Maynor. James E. Mooney. Adam Keith Morgan. Rex L. Mullins. Joshua S. Napper. Howard D. Payne. Dillard Earl Persinger. Joel R. Price. Deward Scott. Gary Quarles. Grover Dale Skeens. Benny Willingham. And Ricky Workman.

我们在这里,怀念29位美国人:卡尔·阿克德、杰森·阿金斯、克里斯多佛·贝尔、格利高里·布洛克、肯尼斯·查普曼、罗伯特·克拉克、查尔斯·蒂莫西·戴维斯、克里·戴维斯、迈克尔·埃尔斯维克、威廉·格里菲斯、史蒂芬·哈拉、爱德华·琼斯、理查德·雷恩、威廉姆·林奇、尼古拉斯·麦考斯基、乔·马克姆、罗纳德·梅尔、詹姆斯·姆尼、亚当·摩根、雷克斯·姆林斯、乔什·纳皮尔、霍华德·佩恩、迪拉德·波辛格、乔尔·普莱斯、迪华德·斯科特、加里·考拉斯、格罗佛·斯金斯、本尼·威灵汉姆、里奇·沃克曼。

Because it would have been useless and dangerous for Pertinax and Alexander, being new princes, to imitate Marcus, who was heir to the principality; and likewise it would have been utterly destructive to Caracalla, Commodus, and Maximinus to have imitated Severus, they not having sufficient valour to enable them to tread in his footsteps.

因为对于同是新君主的佩尔蒂纳切和亚历山大说来,想要模仿那个根据继承权世袭王位的马尔科,不但徒劳无益而且是要吃亏的。同样地,对于卡拉卡拉、科姆莫多、马西米诺说来,想要模仿塞韦罗是极其危险的事情,因为他们没有足够的能力使自己能够追踪塞韦罗。

Also a very special thank you to Roger G Morris and Dave Rowland who have helped so much with this site.

也是一个非常特别的感谢您对罗杰G莫里斯和Dave罗兰谁帮助这么多与此网站。

In the cartoon, Moore's art is supported by MoveOn.org, a left-wing Internet-based interest group that has begun rallying against Roberts' nomination by pointing out Roberts' opposition to clean air acts, promotion of strip-mining, and undermining of the Voting Rights Act, among other things.

在这幅漫画中,莫尔的艺术创作得到了网站MoveOn.org的支持。MoveOn.org是个以互联网为基础的左翼利益团体,它已行动起来反对提名罗伯茨,它指出了罗伯茨的种种问题,其中包括:他反对清洁空气法案、支持露天采矿并破坏"选举权法案"。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。