莫尔

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

It is strange that Courbet Monet is why it did not put pen to paper to stay停笔, Monet said:"I was waiting for the sun."

库尔贝奇怪的是莫奈为什么没有动笔却停笔呆着，莫奈说："我在等太阳。"

Among the most celebrated were Roland of Cremona, Hugh of Saint Cher, Richard Fitzacre, Moneta of Cremona, Peter of Tarentaise, and Robert of Kilwardby.

其中最有名的被罗兰的克雷莫纳，休圣雪儿，理查德fitzacre ， moneta的克雷莫纳，彼得的塔朗泰斯，和罗伯特的基尔沃比。

Roman Abramovich is chasing 15million-rated Croat midfielder Luka Modric in a bid to make Chelsea more entertaining.

罗曼·阿布拉莫维奇为了让切尔西变得更加愉悦人，正在追逐身价1500万英镑的克罗地亚中场球员卢卡·莫德里奇。

The presence of guttural sounds, diacritic aspirations, epenthetic and servile letters in both languages: their antiquity, both having been taught on the plain of Shinar 242 years after the deluge in the seminary instituted by Fenius Farsaigh, descendant of Noah, progenitor of Israel, and ascendant of Heber and Heremon, progenitors of Ireland: their archaeological, genealogical, hagiographical, exegetical, homiletic, toponomastic, historical and religious literatures comprising the works of rabbis and culdees, Torah, Talmud, Massor, Pentateuch, Book of the Dun Cow, Book of Ballymote, Garland of Howth, Book of Kells: their dispersal, persecution, survival and revival: the isolation of their synagogical and ecclesiastical rites in ghetto S.

218两种语言都有喉音、区分的气音、增音以及附属性的字母。两种都是古老的语言，大洪水后二四二年，费尼乌斯。法赛在西纳尔平原所创办的学院就开了这两种语言的课程。他是以色列民族的祖先挪亚的后裔；又是爱尔兰民族的祖先埃贝尔与赫里蒙的始祖。用这两种语言写成的考古学的、系谱学的、圣徒传记学的、注释学的、布道术的、地名研究的、历史的以及宗教方面的著作，其中包括犹太法学博士和神仆团团员的著述：托拉、《塔木德》、马所拉本、《五经》、《牛皮书》、《巴利莫特书》、《霍斯饰本》、《凯尔斯书》，记述这两个民族的离散：，受迫害，幸存，复兴。

Carrefour is France's largest supermarket chain, Louis Vuitton France - to win Hennessy Group has increased by the second-largest shareholder as the first major shareholders, France Louis Vuitton - to win the group Hennessy Louis Vuitton, Dior, Effendi, Jiao Portland, Clinique, Kenzo Sifulan cosmetics stores, as well as Hennessy such as wine, champagne and cognac brands, Louis Vuitton has amounted to - depends on a lot of money donated, Canada The torch relay on the Paris streets to see the process of the French people support Tibet independence, and there is no reason to give French people send money to buy their goods, please remember these brands: Carrefour, marked cars, iron - Long car, Luoyiweide, L'Oreal, Chanel, Lancome.

家乐福是法国最大的超市连锁集团，目前法国路易威登-莫特轩尼诗集团已经由第二大股东上升为第一大股东，法国路易威登-莫特轩尼诗集团旗下路易威登、迪奥、芬迪、娇兰、倩碧、Kenzo 丝芙兰化妆品卖场，以及轩尼诗等葡萄酒、香槟酒和干邑品牌，路易威登曾经给达-赖捐过不少钱，加上这次巴黎圣火传递过程中看见满街的法国人支持藏独，实在没有有理由再给法国人送钱买他们的商品，请大家记住这些牌子：家乐福、标志汽车、雪铁龙汽车、路易维登、欧莱雅、香奈尔、兰蔻。

Cast ::, Gene Hackman as Henry Hearst, Morgan Freeman as Captain Victor Benezet, Thomas Jane as Detective Felix Owens, Monica Bellucci as Chantal Hearst, Nydia Caro as Isabella, Miguel ngel Suárez as Superintendent ..

演员：：，金哈克曼亨利赫斯特，摩根弗里曼船长维克托贝尼泽特，托马斯简费利克斯欧文斯作为侦探，莫妮卡贝鲁奇作为尚塔尔赫斯特，尼迪亚卡罗为伊莎贝拉，米格尔安赫尔苏亚雷斯院长。。。

International touring includes major festivals or seasons in London, Paris, Rome, Spoleto, Athens, Istanbul, Amsterdam, Madrid, Segovia, Santander, Lisbon, Turin, Reggio Emilia, Bari, Palermo, Syracuse, Catania, Cremona, Brescia, Florence, Zurich, Innsbruck, Mexico City, Guanajuato, Bogota, Caracas, Auckland, Wellington, Tokyo, Singapore, Hong Kong, Seoul, Pusan, Perpignan, Reims, Clermont-Ferrand, Cologne and Heilbronn.

悉尼舞蹈团巡演于世界各地的艺术节，包括伦敦、巴黎、罗马、斯波莱托、雅典、伊斯坦布尔、阿姆斯特丹、马德里、塞哥维亚、桑坦德、里斯本、都林、雷焦艾米利亚、巴厘、巴勒莫、锡拉丘兹、卡塔尼亚、克雷莫纳、布雷西亚、佛罗伦撒、苏黎世、伊斯布鲁克、墨西哥、瓜纳瓦托、波哥达、加拉加斯、奥克兰、惠灵顿、东京、新加坡、香港、汉城、釜山、Peerpignan、兰斯、克莱蒙费朗、科隆和海尔布隆。

A long string of popular albums resulted, including Mein Liebeslied (2000), Napoli Adieu (2001), Drei Stimmen d'Amour (2001; co-featuring Mara Kayer and Francine Jordi), Mein Gefьhl (2002), Das Beste von Monika Martin (2002), Himmel aus Glas (2003), Eine Liebe Reicht fьr Zwei (2004), Ave Maria: Lieder zur Stillen Zeit (2004), Ein Kleines Glьck (2005), Schmetterling d'Amour (2005), Heute Fьhl' Ich Mich Wie Zwanzig (2006), and Aloha Blue (2007)- most of which were Top 20, if not Top Ten, hits in Austria and anywhere from Top 50 to Top 100 hits in Germany.

专辑的流行造成一长串，包括炒面Liebeslied（2000年），那不勒斯再见（2001年），科特迪瓦爱德雷伊之声（2001；合作具有马拉戈耶尔和弗朗辛霍尔迪），炒面Gefьhl（2002年），达斯Beste马丁冯莫妮卡（2002年），希默尔澳大利亚玻璃（2003年），Eine利伯Reicht黵Zwei（2004年），圣母颂：之歌楚Stillen宰特（2004），艾因KleinesGlьck（2005年），Schmetterling德爱（2005年），霍伊特Fьhl'非物质文化遗产密歇根魏Zwanzig（2006年），和阿罗哈蓝色（2007）-其中大部分是前20，如果不是前十名，在奥地利安打，任何地方从50强的前100点击在德国。

As for Holberg,—the Muse is cosmopolitan, she has bound him up in one volume with Moliere, Plautus, and Aristophanes, but reads Molière most.

对于荷尔堡，嗨，女神是一个大同主义者，她把他与莫里哀、普拉图斯和阿里斯多芬的作品装订在一起，不过她只喜欢读莫里哀。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐