药理学

Some important nACh receptor-associated proteins effect the robust expression in cell line...

胞内磷酸化的调节作用为今后受体药理学特性的研究提供了新方向。

The exact neuroanatomical substrates underlying each effect of THC are, however, not known.

他们获得的引起THC特殊作用的神经本质能精确解释大麻化学成分的药理学作用。

The I_ on PC12 cells proved to be generated through activation of the neuronal nicotinic receptor.

药理学鉴定表明，PC12细胞上的I_是通过ACh激动烟碱受体引起的。

The IACh on PC12 cells proved to be generated through activation of the neuronal nicotinic receptor.

药理学鉴定表明，PC12细胞上的IACh是通过ACh激动烟碱受体引起的。

Results Many neuronal cell bodies and fibers with dense mGluR7-like immunoreactivity were intensely distributed in the island of Calleja,hippocampus,dentate gyrus,medial habenular nucleus,olivary pretectal nucleus,zonal layer of the superior colliculus,superficial layers of the caudal spinal trigeminal nucleus,paratrigeminal nucleus,raphe magnus nucleus,raphe nucleus pallidus,locus coeruleus,superficial layers and lateral spinal nucleus of the spinal cord.

近年来，大量生理学和药理学实验表明，Glu还可通过与G蛋白偶联的一类受体来调节兴奋性突触的活动和神经元的兴奋性，此类受体被命名为代谢型谷氨酸受体(metabotropic glutamate receptors，mGluRs)。目前应用分子生物学技术已成功地克隆出mGluR的8种亚型(mGluR1-8)［2～7］。

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

With the development of study in pathogenesy of glaucoma and pharmacology, it have made a great progress in anti-glaucoma drug.

随着人们对青光眼发病机制的研究以及药理学知识和技术的发展，抗青光眼药物也有了很大进展。

To understand the role of pharmacogenetics, pharmacokinetics and pharmacodynamic in the psychopharmacological treatment of different ethnic group.

目的： 1 、理解遗传药理学、药代动力学、药效学对不同种族人群的精神药物治疗的作用。

We hope you will concentrate primarily on pharmacologic issues and not get bogged down on interesting clinical sidelights.

我们盼望学生将注意力集中在药理学课题上，而非陷於有趣的旁枝细节的繁琐当中。

We hope you will concentrate primarily on pharmacologic issues and not get bogged down on interesting clinical sidelights.

我们盼望学生将注意力集中在药理学课题上，而非陷于有趣的旁枝细节的繁琐当中。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。