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The binding of three drugs to HSA induces the transformation of Raman spectra of tryptophan residue.

3药物的结合改变了酪氨酸的拉曼光谱。这表明酪氨酸的外环境发生改变。

The proportions of mono-drug resistant Tubercle bacillus have a decreasing trend year by year, but those of multi-drug resistant Tubercle bacillus still keep in a very high level.

各种抗结核药物的单药耐药情况虽有逐年下降趋势,耐多药结核杆菌维持在高水准,将给结核病的治疗带来一定的困难。

Methods Beagle dog liver microsomes were prepared by using ultracentrifuge method. After incubating 0.4 μmolL^(-1) MN9202 with 1 gL^(-1) microsomes for 30 min at 37℃, the reaction was terminated by adding 0.5 mL alkalization. The RP-HPLC was used to determine the drug in the incubation mixture.

差速离心法制备Beagle犬肝微粒体酶,0.4μmolL^(-1)的MN9202与1.0gL^(-1)的肝微粒体酶在37℃水浴中孵育30min,加入0.5mL碱化液终止反应,然后采用RP-HPLC法测定孵育液中MN9202原形药物的浓度。

Ben Yeoh, an analyst with Dresdner Kleinwort, told United Press International he thought the FDA's position still left it up for the committee to determine whether the drug's benefits were worth the risks.

Dresdner Kleinwort的一位分析师Ben Yeoh告诉合众社记者,他认为FDA所处的地位仍会使其考虑让委员会来决定该药物的效果是否值得冒险。

With Prohaler?, Valois Pharma, the world leader in nasal and pulmonary drug delivery devices, and partner of major pharmaceutical companies, is contributing to the enhancement of patient compliance, which will lead to improved drug effectiveness, especially in the treatment of asthma and COPD.

随着Prohaler,瓦卢瓦制药,在鼻腔和肺部给药装置世界领先地位,主要制药公司的合作伙伴,有助于病人的情况,这将导致改善药物的有效性,特别是在治疗哮喘和慢性阻塞性肺病,增强。

Therefore, to promote the expression and secretion of NTF, and alterate differentiated direction of NSC would become action target of various drug treating ICH.

因此,提高内源性神经营养因子的表达和分泌,改变神经干细胞的分化方向,都将成为各种脑出血治疗药物的作用靶点。

Aminoquinoline is one of the most prominence, its beneficial effects in the management of malaria caused huge attention in the pharmacologic research. The first antimalarial for clinic use was stem from AQ, since then, plenty of new structures with higher effect have been discovered.

氨基喹啉类衍生物是其中最为显著的一种,在对抗疟疾药物的研究中受到极大关注并最早应用于临床,多年来对其深入研究也涌现了一批更高效的新结构。

It has become attractive to asymmetrically synthesize of chiral drugs through "environmentally friendly" biotransformations.

利用&环境友好&的微生物或酶催化方法进行手性药物的不对称合成已成为一个极具吸引力的方向。

The asymmetric hydrogenation of prochiral ketones is one of the most efficient methods of producing enantiomerically enriched secondary alcohols. The ruthenium complex RuCl_2[P(C_6H_5)_3]_2--DPEN(DPEN=1, 2-diphenylethylene-diamine) was applied to the asymmetric hydrogenation of benzalacetone.

具有光学活性的烯丙基醇是合成许多生理活性药物的重要中间体,前手性酮不对称加氢反应是制备具有光学活性仲醇的一种重要方法。

Betulin, a naturally occurring triterpene, available in abundance up to 10% dry weight of bark from white birch bark, seems to be an ideal starting material for the synthesis of betulinic acid.During a discovery effort from natural resources, in order to seek new biologically active compounds, reaearch on chemical modifications of valuable precursors have been demonstrated to be an effective path to resolve the water solubility problem and increase bioavailability.

从自然界寻找先导活性化合物,再进行结构修饰,试图提高其活性,降低其毒副作用,并提高其水溶性,是创新药物的一条重要思路,而且在新药研制中也得到了很好的应用并取得了显著的成绩。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。