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According to the structure-activity relationships, we have designed five novel indoline derivatives and have synthesized three of them. Some animal evaluations are under way.

药物的构效关系出发,我们设计了五种二氢吲哚氧苯甲酸类新化合物并完成了其中三个的合成,目前已在做动物试验。

Objective:To observe Spironolactone on ventricular structure during the subsequent stages after infarction by setting up an infarcted model of rat.

目的:探讨螺内酯对大鼠心肌梗死后不同阶段左室结构变化的影响,为心梗后心脏保护药物的使用提供依据。

Observing localization of the drug and morphologic change in DRG cells and motor neurons in spinal cord anterior hom after 1% adriamycin intraneural injection into the sciatic nerve of rabbits. Moreover, evaluating sensory and motor function 1-8 weeks following injection. Exploring whether the agent, injected into sciatic nerve, has the effect of chemo-ganglionectomy on the corresponding DRG.

研究家兔坐骨神经内注射1%阿霉素后,药物的聚集部位及相应脊髓前角运动神经元和背根节细胞的形态学变化,测定家兔1~8周下肢感觉及运动功能,探讨坐骨神经内注射阿霉素能否对相应背根神经节产生化学切除术作用。

Generally,the ionizable salt of the drug ismore water soluble than the free acid or free base.

通常,药物的电离的盐比自由酸或自由基地溶于水。

The aim of this brief review is to discuss the safe contrast administration in radiological examination process, including iodinated contrast medium induced extravasations, allergy, and nephrotoxicity via intravenous route; gadolinium induced nephrogenic systemic fibrosis, attention information on other contrast medium or medications.

本文将讨论放射线检查之用药安全流程,包括注射含碘对比剂造成渗漏、过敏或对比剂造成的肾毒性;注射含钆类对比剂发生肾因性全身纤维硬化症、其他对比剂或药物的注意事项。

Each step involved in neurohumoral transmission represents a potential point of drug attack.

神经递质传递中的每一步都可作为药物的潜在作用点。

In this thesis, application of direct and indirect oscillographic determination methods in pharmaceutical analysis was investigated.

本论文主要开展药物的直接和间接示波测定方法的应用研究。

Observing distribution of the drug and it's effect on DRG cells after paravertebral injection with 0.1-1% adriamycin in rabbits. Investigating whether adriamycin entered selectively into DRG and damages DRG cells.

目的:1。研究家兔椎旁注射0.1~1%阿霉素后,药物的聚集部位及其对背根神经节细胞的影响,探讨阿霉素能否选择性进入背根神经节并损伤背根节细胞。2。

However, the drug only allows a low absorption and bioavailability via peroral routes.

壳聚糖能够打开消化道上皮间的紧密连接,增加药物的透膜吸收。

This review covers the application of bioreduction to the saymmetric synthesis of pharmacologically active compounds on a alboratory and a commercial scale.

综述了近年来利用生物还原方法进行制备量和商业规模的不对称合成手性药物的进展。

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。

Its advantage is that it can be used in smaller units.

其优点在于可以在较小的单位中应用。