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Second,the development trend and research status of fluoroquinolones was presented. Fluoroquinolones,which were newly-developed oral comprehensive antibiotics in recent years,has fairly strong flurorescent quality and therefore is used to explore the functional mechanism of drugs in human bodies,by the change of fluorescent extensity between fluoroquinolones and protein,as well as metallic irons.

其次是氟喹诺酮类药物的发展趋势及研究进展,氟喹诺酮类的药物是近年来迅速发展的口服广普抗菌药,具有较强的荧光特性,因此可以利用其与蛋白质及金属离子相互作用时荧光强度的变化来研究药物在人体内的作用机制等。

At the same time, the research of innovation drugs involves a series of important science foreland problem, and its center is the structure and function of macromolecule, the target of drug effect, a...

同时,创新药物的研究涉及一系列重大的科学前沿问题,其中心就是药物作用的靶标生物大分子的结构、功能及其与药物的相互作用。

They list dofetilide, moxifloxacin, quinidine, sotalol, sparfloxacin and thioridazine, but point out that this list is not exhaustive. 4 A much longer list of QT-prolonging drugs is to be found in table 4.3 in the monograph 'Drugs that prolong the QT interval + Other drugs that prolong the QT interval'.

他们列出了多非利特,莫西沙星,奎尼丁,索他洛尔,司帕沙星和硫利哒嗪,但指出在此列出的并不详尽。4在专题论文的表4.3中有一份长得多的关于延长QT间期药物的列表"延长QT间期的药物+其他能延长QT间期的药物"

The synthesis of chiral pharmaceuticals is a hot issue of the development in pharmaceutical in the world,asymmetric hydrogenization of which is the successful technology in the chiral synthesis .

手性药物的合成是目前全球药物开发研究的热点,而不对称氢化是手性合成中最成熟的技术。讨论了不对称氢化技术在镇痛类、抗生素类、抗菌类、抗忧郁类以及维生素类等9类手性药物合成中的实际应用

Depressed patients with bipolar features are both less likely to respond to antidepressants and more likely to have tolerability problems with these drugs, possibly because they elicit hypomanic symptoms such as agitation and sleep disturbance, said Dr. Sharma. What is less known is whether these bipolar features are subtle enough for clinicians to miss them if they are not careful.

Sharma博士指出,有双极特征的忧郁症病患对于抗忧郁药物的反应可能比较不好,而且对这些药物较可能有耐受性的问题,可能是因为这些药物会造成轻躁性症状,例如躁动、睡眠障碍;目前仍不清楚双极性症状的病征是否会使得临床医师忽略这个症状,如果他们不小心的话。

Depressed patients with bipolar features are both less likely to respond to antidepressants and more likely to have tolerability problems with these drugs, possibly because they elicit hypomanic symptoms such as agitation and sleep disturbance, said Dr. Sharma. What is less known is whether these bipolar features are subtle enough for clinicians to miss them if they are not careful.

Sharma博士指出,有双极特徵的忧郁症病患对於抗忧郁药物的反应可能比较不好,而且对这些药物较可能有耐受性的问题,可能是因为这些药物会造成轻躁性症状,例如躁动、睡眠障碍;目前仍不清楚双极性症状的病徵是否会使得临床医师忽略这个症状,如果他们不小心的话。

Posteroventral pallidotomy can abolish all Parkinson's symptoms including pharmaceutical complicati...

发挥药物的最大功效,外科治疗药物的不足并从根本上消除或缓解药物治疗的不良反应,是当前PD治疗的新策略

ObjectiveTo study the clean production technology of diosgenin. MethodsThe diosgenin was extracted by prefermentation,separation, enzymic hydrolysis, prefermentation and fermentation by A.niger and double-separation.

皂素又名皂苷元,难溶于水,易溶于苯、氯仿等有机溶剂,是一种重要的甾体激素药物合成原料,主要用于脑体激素类药物的合成,如黄体酮、抗多灵、口服避孕药等药物合成原料,在医药生产中具有十分重要的应用价值,有&药用黄金&的美称[1]。

Suitable implants, composite drug membranes, implanting under scleral flap for glaucoma or into suprachoroid space for perforating ocular injury were developed in this paper. The model drug in film could maintain sustained release. Thus it was advantageous to alleviate side effect to ocular tissue with an acute change in drug concentration and enhance utilization of drug.

本文旨在研究适于手术治疗青光眼和眼穿通伤的植入剂-复合药膜,植入脉络膜上腔或巩膜瓣下,维持模型药物的持续释放,有效避免药物的峰谷现象对眼组织的毒害作用,提高药物利用率。

The percentage of BZ hypnotics DDDs was always above 98%.

共中,BZ类药物所占的年销售金额比例虽有下降的趋势,但仍占绝大多数;BZ类药物的年度总DDDs比例仍占98%以上,所有NBZ药物的排名均在末位。

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My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

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