药物的

FQNs shares the anti-infection medicine to don't greatly differ with the medicine amount of money,the application each year of frequency percentage.during the period 2000~2005,used the biggest species in the medicine amount of money were an floxacin,qurinodis,rufloxacin,rufloxacin,Gatifloxacin,lomefioxacin respectively,has 22.36%,18.05%,46.16%,22.55%,34.43%,23.8% that FQNs of that year always uses the medicine amount of money respectively.

笔者对2001年~2005年我院门诊氟喹诺酮类药物的用药情况进行较全面的分析，以期了解氟喹诺酮类药物在我院门诊用药的现状和趋势。1资料与方法1.1资料来源资料来源于我院电脑数据库。1.2方法统计2000年~2005年我院氟喹诺酮类药物的用药金额及在抗菌药

The theory is cell kinetics and mechanism of drugs.

主要是根据细胞动力学原理和药物的作用机理分析，如果把药物集中应用，一方面只是一过性的杀灭增殖期的白血病细胞，对静止期细胞影响不大，另一方面对正常细胞造成较大损伤，而如果药物作用于几个细胞增殖周期，对白血病细胞进行几个循环的打击，会清除更多白血病细胞，而对正常细胞损伤较小。

The reality is somewhat less glowingly positive than those media reports indicated.

为保证数据的可靠性，试验过程中，无论是实验人员还是接受药物的女性，都不知道他们所用的是何种药物以及该药物是用于治疗何种疾病的。

Treatment recommendations include simplifying the pain regimen, avoiding polypharmacy with its risk of drug interactions, and beginning drugs at lower dosages and titrating upward as needed.

推荐的治疗方法包括给以单一的止痛药物，避免给予多种混合药物以避免药物的互相影响，从低剂量开始给药并根据需要一点一点的增加用量。

Results The relationship between permeability coefficient and oil/water partition coefficient of 17 alkaloidal drugs or drugs containing 2%Azone can be described as following equations.logkp=7.35×10-2-3.079×10-2logk-8.112;logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272,respectively.

结果生物碱类药物的经皮渗透系数与药物油/水分配系数的关系式为：logkp=7.35×10-2-3.079×10-2logk-8.112；logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272；结论 17种药物的油/水分配系数平均最佳值为2.83，含2%氮酮后的其平均最佳值为3.17。

Stabilized, hypophosphorylated β-catenin translocates to the nucleus, where it interacts with transcription factors of the TCF/LEF-1 family, leading to the increased expression of genes, such as c-myc and cyclin D1

那么，药物的作用有以下几个可能性：2。药物促进或抑制catenin的核转位，但不影响其磷酸化程度3。药物可直接磷酸化catenin或直接使其去磷酸化，即具有磷酸激酶或磷酸酶的作用。

Biopharmaceutics is the science which investigates the absorption, distribution, metabolism, Elimination of dugs and preparations, elucidate the interrelationship between the dosage form and biologic agent and curative effect.

生物药剂学》是研究药物及其制剂在体内的吸收、分布、代谢和排泄过程，阐明药物的剂型因素，机体生物因素和药物疗效之间相互关系的科学。

Once the prodrug is in the blood supply, esterases hydrolyse the ester to unmask the carboxylate group and the drug can interact with its target.

药物的醚作为前体药物，口服作用时，由于醚把羰基官能团的极性遮掩了，前体药可以穿越肠内壁的细胞膜，一旦前体物进入血液循环，就会发生水解暴露出羰基使药物与目标相互作用。

In this study, we compared the efficacy and side-effectprofiles of morphine and hydromorphone at concentrations producingequivalent drug effect measured by pain score and miosis.

在这个研究中，我们比较在产生相同药物效应的药物浓度时，吗啡与氢化吗啡的效能和副作用特性。药物的效应通过疼痛评分和瞳孔缩小来确定。

Because elderly patients with a lower basal metabolism, body reserve capacity is poor, and drug metabolism in liver and kidney functions closely related to the poor so that a reduced ability to excrete drugs, high blood concentration, and therefore need to take full advantage of the process of medication dosage, to ensure the safety of the treatment.

由于老年患者基础代谢较低，机体储备能力差，与药物代谢关系密切的肝肾功能不佳，从而使药物排泄能力下降，血药浓度偏高，因此在用药过程中需要充分把握药物的剂量，保证治疗的安全性。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。