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However, the clinical use of DOX is limited by its severe, cumulative, dose-dependent cardiotoxicity.

功能基因组学技术在新药研发和药物安全性评价中的应用,为药物毒理学家预测药物的毒性和研究毒作用机制提供了崭新的理论和手段。

We can mak use of the combination of two policy. Suggestions: In order to improve RUD in rural areas of China and RUD researches, the researcher suggested: 1.Pay more attention to the manager's impact on improving RUD and make use of its paradigm and leading impact. 2.Apply ten core interventions including STG and EDL. They are applying STG, applying EDL, developing a drug management department and perfecting its function, educating health workers, supervising and checking up the use of drugs, developing independent drug information system, carrying out public education, economic interventions, improving the work rate of drug use and health workers by ensuring sufficient budget. 3. Make use the pressure of applying the new-type CMS and apply many types of interventions to improve RUD in rural areas.

建议:为进一步促进农村地区合理用药,完善农村地区合理用药研究,建议: 1、重视乡镇卫生院院长在促进合理用药中的作用,充分发挥其示范、带动作用; 2、实施以临床诊疗规范、基本药物目录为主的十条核心干预措施,具体包括:实施临床诊疗规范、实施基本药物手册、建立医院药事管理机构,完善相关职能、开展医务人员培训、开展用药督导和审核、建立独立的药物信息提供体系、开展药物的公共教育、经济措施、保证政府投入以提高用药和医务人员的工作效率; 3、利用实施新型农村合作医疗制度的压力机制,综合使用多种措施协同促进合理用药; 4、多部门协作共同促进农村地区合理用药,由合作医疗和医疗救助等保障制度管理部门、财政部门、卫生行政部门、药品监管部门、工商行政部门、物价部门、媒体等共同参与,各司其责,共同促进农村地区合理用药; 5、在合理用药评价研究中应密切注意农村地区药品利用不足问题,建立正确的评价假设; 6、构建适合我国国情的完善的合理用药干预措施效果评价指标体系,加强标准值研究。

The process of drug evaluation is the process to search and understand drugs.

药物的评价过程,就是寻找药物与认识药物的过程。

Medication Dosing in Renal Failure In addition to avoiding nephrotoxic agents in the setting of acute renal failure, medications that are eliminated by the renal route require dosing adjustments.

登录后回答可以获得经验值奖励,并可以查看和管理所有的回答。登录|在药物治疗肾功能衰竭的配料除了避免在急性肾功能衰竭,这是由肾脏清除药物的路线设置肾毒性药物需要剂量调整。

This course mainly includes the basictheories of Drug Toxicology, the toxic effects of drugs and their assessing methods, as well as the application of Drug Toxicology in the nonclinical drug safety evaluation.

本门课程主要包括药物毒理学基础理论,药物的各种毒性作用和评价方法,以及药物非临床安全性评价的毒理学研究内容。

Osteoarthritis is a degenerative disease that disunites the extra cellular matrix of articular cartilage and is arduous to cure because cartilage is a complex and nonvascular tissue. Treatment of OA has targeted modifiable reagent to be the connective tissue structure-modifying agents and disease- modifying osteoarthritis drugs, such as hyaluronic acid or modified tetracycline.

退化性关节炎是一种缓慢渐进式的退化性疾病,目前治疗关节炎药物的研究重点,在於进一步修饰已知传统药物之官能基,使其成为具有改善连结组织结构以及减缓关节炎症状之药物。

Usage: useful for pharmaceutical intermediate,especially useful for intermediate of synthesis aids inhibitor and high temperature resistant resins and metallocen catalyst for olefine polymerization.

用途:用作各种医药合成中间体,特别是抗艾兹病药物,治疗糖脲病药物以及治疗心律不齐病药物的中间体以及烯烃聚合用金属茂络合物催化剂配位体和透明的耐热性树脂原料。

Pang's death was 'combined intoxication' from seven drugs found in his system, according to a written report from the Orange County Sheriff-Coroner. The drugs included oxycodone, hydrocodone and two other painkillers, along with drugs generally used to treat depression and anxiety.

加州橘县验尸官办公室在一份书面报告中称,彭日成死于体内七种药物的复合中毒;这些药物包括:中枢神经系统镇痛药羟考酮、镇咳药氢可酮和其他两种止痛药,此外还有通常被用于治疗抑郁及焦虑的药物。

The cause of Mr. Pang's death was 'combined intoxication' from seven drugs found in his system, according to a written report from the Orange County Sheriff-Coroner. The drugs included oxycodone, hydrocodone and two other painkillers, along with drugs generally used to treat depression and anxiety.

加州橘县验尸官办公室在一份书面报告中称,彭日成死于体内七种药物的复合中毒;这些药物包括:中枢神经系统镇痛药羟考酮、镇咳药氢可酮和其他两种止痛药,此外还有通常被用于治疗抑郁及焦虑的药物。

Any use of barbiturates and opiates was associated with increased risk of TM after adjusting for covariates, while triptans were not.

调整变量后,任何巴比妥类药物和阿片类药物的服用与TM发生风险的增加具有相关性,而曲坦类药物则没有相关性。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。