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药物治疗

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It can effectively inhibit the replication of HIV in T lymphocyte and mononuclear/macrophagocyte.

八十年代末以来的国内外许多研究工作表明,天花粉蛋白是一个潜在的艾滋病治疗药物,它能够有效地抑制T淋巴细胞以及单核/巨嗜细胞内HIV病毒的复制,九十年代初,美国一些研究单位开始利用天花粉蛋白进行临床治疗治疗艾滋病患者实验。

Thirty two point six percent (42/129) of menopausetransition women and 18.9%(60/318) of menopause women had breast structure changes,〓=9.26, P<0.01. The frequency of breast structure changes decreased with decreasing ofserum of 〓 level and increasing of age. Four (4/29, 13.8%) in HRT group had breaststructure changes, which disappeared after discontinuing HRT or reducing the dose of HRTin 3 subjects. Conclusions: Most of normal menstrual women and menopause transitionwomen experienced Mastalgia; Mastalgia occurred in 89.7% of subjects and lasted forabout 2 M. in the 1-year ccHRT; Image of breast ultrasound changed following menstrualcycle in normal menstrual women; Breast pain and breast structure change may be causedby higher 〓 and P level in luteal phase; The breast structure changes of HRT user weresimilar to that in normal women and were reversible.

大部分正常月经妇女和绝经过渡期妇女有周期性乳房胀疼,绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年中大部分使用者有持续约两个月的乳房胀疼;乳腺体层厚度随体内雌孕激素水平的下降和年龄的增加而逐渐萎缩,绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年后,对乳腺体层的厚度没有明显的影响;超声下乳腺结构改变主要受体内雌孕激素水平的影响,正常月经妇女中1/3的乳腺结构改变具有可逆性,绝经过渡期和绝经后妇女中有一半的乳腺结构改变的特征类似正常月经妇女具有可逆性的乳腺结构改变;绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年后,少数使用者出现的乳腺结构改变可随药物剂量的调整或停药而恢复;对长期HRT使用者仍需加强乳腺的监测,长期HRT对乳腺的影响值得进一步研究。

The rate of clinical success, defined as cured plus improved patients, was 75% for levofloxacin and 72.8% for ciprofloxacin (95% confidence interval for the difference in the success rates,-13.27 to 8.87). Microbiologic eradication rates were also similar in both groups (75% for levofloxacin and 76.8% for ciprofloxacin; 95% CI for the difference,-8.98 to 12.58). The most common isolates were Enterococcus faecalis and E. coli . Both regimens were well tolerated, with similar rates of adverse events and of relapse by six months.

治疗成功的定义为患者的病情痊愈并且症状获得改善,结果接受levofloxacin治疗的患者成功率为75%,而接受ciprofloxacin治疗的患者则为72.8%(信赖区间为-13.27 ~ 8.87);两组的微生物根除率相当(levofloxacin组为75%,ciprofloxacin组为76.8%;信赖区间为-8.98 ~ 12.58);最常被分离出的病菌为乳酸球菌与大肠杆菌,这两种药物的耐受性都很好,副作用与六个月的复发率也都相当。

Increased seerity of heart failure or increased number of concomitant medications did not worsen persistence, but nonpersistence identified a high-risk population of patients who required special attention.

心衰恶化或治疗药物数量的增长并不使持续治疗的比例减少,但在高危病人中没有持续治疗值得特别关注。

The U.S. Food and Drug Administration's Oncologic Drugs Advisory Committee voted 10 to 0 that the objective responses seen in the studies were strong enough to serve as a surrogate that was "reasonably likely" to predict clinical benefit as a treatment for patients with previously treated glioblastoma.

食品与药品管理局的肿瘤药物咨询委员会以10:0的投票支持该研究,他们认为该研究有足够的事实依据,证明其可以作为过去曾经接受过治疗的多形性恶性胶质瘤患者的一种&合理的&替代治疗方法,可以预期患者能从该治疗当中获益。

Methods Seventy six aged patients with ostalgia caused by primary osteoporosis, whose T numerus less than certified value 2.5 were randomized into two groups: 1. Applying only CT (36 cases); 2. CT combined with Low frequency transduction pulsed electromagnetic fields (36 cases); Two groups simultaneously were given Calcium 600 mg and injected CT 50IU, ten days later injected 50IU every two days in two months, Low frequency transduction pulsed electromagnetic fields treatment was made by Tianjin Jinxitong company, frequency 20-40Hz, and treated 20 minutes by this machine, totally 30 days. Six months later we examined their Bone density again.

将存在骨质疏松性骨痛同时经DEXA骨密度仪检测T值低于标准值2.0以下的老龄原发性骨质疏松症患者76人随机分为两组:①单纯应用鲑鱼降钙素组(36人);②联合应用药物及低频电磁场组(36人),两组同时每日给予钙而奇D600片1粒,CT按每日肌肉注射50IU,10d后改为隔日肌注50IU连续应用2个月,低频电磁场治疗采用天津金希统公司生产的XT2000B型OP治疗仪,频率为20~40Hz,每天治疗20min,共治疗30d, 6个月后复查骨密度。

The selective retention of Lipiodol in hepatic tumors suggests its potential as a carrier for chemotherapeutic or radiotherapeutic agents for targeted therapy purposes.

因为利比多可以选择性的停留在肝癌组织,所以常用来携带一些化学治疗及放射治疗药物,以达到标靶治疗目的。

"Despite confounding factors, such as concomitant medications which have been associated with skin reactions, several cases reported to described a plausible temporal relationship, positive dechallenge, and/or positive rechallenge supporting an association between infliximab and serious cutaneous skin reactions," the newsletter notes.

这篇安全新闻结论指出,一如蛋白质产品,这3种TNF-alpha拮抗剂潜在致免疫性,且会促使免疫调节严重皮肤反应,如EM、SJS和/或TEN;评估TNF-alpha拮抗剂和严重皮肤反应之间的关联,可能会因为一些共同因子而造成挑战,例如同时服用的1种或多种药物与EM、SJS和/或TEN的关联,当接受TNF-alpha拮抗剂治疗时发生任何的严重皮肤反应须有适当的诊断和治疗,以及考量替代治疗。

Along with the screenage diagnostic technique has developed at full speed, the majority of home and overseas neurosurgeons suggest that the surgical therapy should be the best regime to the Obstinate Epilepsy patients, if the series of clinical therapies, for instance drug, etc, were inefficient.

随着影像学诊断技术的飞速发展,国内外多数神经外科医生们认为在药物等一系列临床治疗均无效的顽固性癫痫采用手术治疗是最佳方案,从而把癫痫的外科治疗作为重点课题进行研究。

In the treatment,the individual patient appears the skin rash,but does not affect the treatment,discovery to heart,liver,kidney function and so on virulent side effect.conclusion: danlu tong supervises the piece is one kind of treatment waist canales spinalis is narrow sickness(stasis anti-to supervise arteries)safely,the effective medicine.

在治疗中,个别患者出现皮疹,但不影响治疗,未发现对心、肝、肾功能等有毒副作用。结论:丹鹿通督片是一种治疗腰椎管狭窄症安全、有效的药物。

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