药物治疗

A medicament for Treating cold, fever and respiratory disease caused by cold and fever comprises therapeutically-effective amount of alcohol extract or acid water extract of Alstonia scholaris L.

治疗感冒、发热及其所导致的呼吸道疾病的药物，该药物含有治疗有效量的糖胶树Alstonia scholaris

RESULTS Duodenal ulcer was the first cause of upper gastrointestinal hemorrhage. Gastric ulcer, cirrhosis, Mallory-Weiss syndrome or acute gastric mucous lesion was the second cause of the illness alternatively. The rate of endoscopy and emergent endoscopy has been going up year after year and got up to 80% in 1998. Bleeding and active hemorrhage, respectively were found in 24.3% and 14.9% of the patients underwent endoscopy before medication. Endoscopic hemostasis was performed in 108 patients by spraying hemostatics and a good response was achieved subsequently. Hemostatics were mainly cimetidine and yunnan baiyao before 1994. Reptilase, pPI, famotidine and ranitidine were used increasingly while cimetidine and yunnan baiyao were used decreasingly. Octreotide was used in patients with cirrhosis commonly. The length of hospital stay and the period from admission to bleeding cease tended to be shorter year by year, but the reduction rate was small. The uses of ranitidine, famotidine, pPI, reptilase, octreotide, early endoscopy and endoscopic therapy may play a role in improving the therapeutic effect of hemostasis, reducing the hospitalization and the mortality.

结果 十二指肠球部溃疡是历年上消化道出血的首要原因，胃溃疡、肝硬变、Mallory -Weiss综合征、急性胃粘膜病变则交替成为第2位出血原因；内镜诊断率和急诊内镜率逐年提高，1998年达到80%，内镜下见出血者占内镜检查的24.3%，而见到活动性出血者仅占内镜检查者的14.9%；内镜下止血108例次，成功率100%；1994年前治疗药物主要为云南白药和甲氰咪胍，之后，随着立止血、质子泵抑制剂、法莫替丁、雷尼替丁等药物使用的逐渐增多，前二者的使用逐渐减少，善得定多用于肝硬变出血；住院天数和止血天数呈逐年下降的趋势，但幅度微小；雷尼替丁、法莫替丁、PPI、立止血、善得定的使用以及及时的内镜检查和内镜下治疗在提高止血效果、缩短住院天数、降低死亡率方面可能起到了一定作用。

Choose medicaments correctly, reasonable use medicaments, in order to make sure with medicine safety is mixed effective will be henceforth the main task that clinical medicine learns, for solution control hospital the clinical current situation that use drug reachs existence issue, promote the development of the reasonable job that use drug, raise a hospital reasonable the level that uses drug, the prescription of two place has outpatient service of author general hospital, be in hospital analytic research, summary goes out unreasonable a few big states that use drug, undertake classified at the same time. 1 clinical unreasonable with medical analysis each division all applies 1 abuse of 1 · or antibiotic of blind application antibiotic extensively, utilization rate amounts to 70% above, among them couplet is used rate be as high as 40%, appear even 2 couplet, triplex above, the commonnest abuse is infection of the upper respiratory tract, be admitted to hospital give 2~3 to plant antibiotic cure. 1 · of 1 · 1 without point to this kind to the cure that ask for uses drug unreasonable with medicine main show is in the person that the virus sex appeal such as hepatitis of sex of common cold, chicken pox, berpes zoster, virus is caught, in infection of not amalgamative bacterium, point to without what apply antibiotic ask for next using medicine. Incontrollable virus affects antibiotic, increase hepatic burden instead to patient of virus sex hepatitis.

梗概： 正确选择药物，并合理使用药物，以保证用药平安和有效是今后临床药学的重要任务，为了解把握医院临床用药目前状况及存在新问题，推动合理用药工作的发展，提高医院合理用药的水平，笔者将医院门诊、住院两处的处方进行分析探究，总结出不合理用药的几大状况，同时进行分类。1临床不合理用药的分析1·1滥用或盲目应用抗生素抗生素各科均广泛应用，使用率达70%以上，其中联用率高达40%，甚至出现二联、三联以上，最常见滥用为上呼吸道感染，入院给予2~3种抗生素治疗。1·1·1无指征的治疗用药这类不合理用药主要表现在普通感冒、水痘、带状疱疹、病毒性肝炎等病毒性感染者，在未合并细菌感染，无应用抗生素的指征下用药。

This study not only implicated a possible accession for the management of diseases characerised by pathological cell proliferation using drugs targeting PI3K/PTEN/PKB signal system, but also afforded theory evidence for the ideal results of the two agents in the prevention and treatment of atherosclerosis and restenosis after interventive myocardial reperfusion.

此项研究不仅为研制PI3K/PTEN/PKB调节药物用于以细胞过度增生为主要病理改变的疾病治疗展示了可能途径，更为该两种药物在冠心病一、二级预防或冠脉介入治疗后再狭窄防治中取得的理想疗效提供了理论支持。

In recent years introduced osteoarthropathy to treat the medicine one after another "MUJIECapsule ", the Japanese special effect to fall the blood fats health foods "QINGQING oral", the national three kind of new medicine white plague treatment medicine QIBEI capsule, as well as mainly treated the neurasthenia, the losing sleep forgetful own variety -- YANGSHENGUILING oral and so on many heavyweight own varieties, the enterprise during creation huge economic efficiency, caused the general patients to be far away from indisposition suffering.

近年来陆续引进了骨关节病治疗药物&木竭胶囊&、日本特效降血脂保健食品&清清口服液&、国家三类新药肺结核病治疗药物芪贝胶囊，以及主治神经衰弱、失眠健忘的独家品种--洋参龟灵口服液等多个重量级独家品种，企业在创造巨大经济效益的同时，使广大患者远离了病痛的折磨。

In recent years introduced osteoarthropathy to treat the medicine one after another "wooden to use up the capsule", the Japanese special effect to fall the blood fats health foods "the clear oral", the national three kind of new medicine white plague treatment medicine qi shell capsule, as well as mainly treated the neurasthenia, the losing sleep forgetful own variety -- foreign ginseng turtle spirit oral and so on many heavyweight own varieties, the enterprise during creation huge economic efficiency, caused the general patients to be far away from indisposition suffering.

近年来陆续引进了骨关节病治疗药物&木竭胶囊&、日本特效降血脂保健食品&清清口服液&、国家三类新药肺结核病治疗药物芪贝胶囊，以及主治神经衰弱、失眠健忘的独家品种--洋参龟灵口服液等多个重量级独家品种，企业在创造巨大经济效益的同时，使广大患者远离了病痛的折磨。

The improvement of preparation of the compound after the capsule in the treatment of bone fractures with the traditional technique of compound osteosynthesis capsules compared with obvious effect, safety, no significant side effects, most of the patients in the application of a drug the first course of treatment that is swelling, pain effect a treatment for various parts of the fractures, dislocation, as well as various parts of the body's soft tissue injury of effective drugs.

改进制备工艺后的复方接骨胶囊治疗骨折方面与传统工艺的复方接骨胶囊比较具有疗效明显、安全、无明显毒副作用，多数病人在应用药物第1个疗程即有消肿、止痛效果，是一种治疗各种部位的骨折，脱位以及身体各部位的软组织损伤的有效药物。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Treatment:①medicine therapy: cabamazepine, large dose of vitamine B12, phenytoin sodium;②nerve blocking or surgery:③stereotactically controlled thermocogulatin of trigeminal roots using a radio-frequency generator; microvascular decompression

与症状性三叉神经痛相鉴别。4，治疗：①药物：卡马西平，B12，鞍莫钠；②封闭：无水酒精注射；③射频热凝；④手术治疗，首选药物为卡马西平

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。