药物处理

At the same time, intracellular DNA was extracted and subjected to Southern blot, hybridized with a ~(32)P-labeled HBV probe and autoradiographed. The intensity of the autoradiographic bands was quantitated by densitometric scans of computer and ED_(50) was calculated.

然后以2.2.15细胞培养为基础，用不同浓度的β-L-D4A进行干预后，经ELISA检测上清液中HBsAg及HBeAg的含量，提取病毒DNA后进行Southern印迹、~(32)P标记HBV探针杂交、放射自显影，经计算机图像处理进行定量分析，求出50％抑制的药物浓度，即EC_(50)。

PA-457 was not just another Taxol, the anticancer drug that required the controersial felling of rare yew trees until a semisynthetic substitute was found. Panacos did not need a steady source of Taiwanese herbs. Betulinic acid could be extracted from ubiquitous plane and birch trees, and a subsequent processing step yielded the desired molecule.

PA-457不像抗癌药物太平洋紫杉醇：在太平洋紫杉醇的合成代替品出现前，砍伐罕见的太平洋紫杉一直引发争议；Panacos并不需要有稳定供应的台湾药草，桦木酸能从普遍存在的悬铃树和桦树中提炼，并且只要一个后续处理步骤，就可以制造出所需的分子。

Methods: NCI - N87 cells were treated by matrine in different concentrations and variablc durations. Ceil growth and proliferation were observed by CCK - 8 assay.

方法NCI—N87细胞经不同浓度苦参碱处理后，采用CCK-8法检测药物对肿瘤细胞的抑制作用，观察细胞形态学改变，检测细胞DNA分布。

The various parameters observed were the following : modification of the skin status, coat, eyes, mucous membrane, apparition of secretions or excretions and neurovegetative reaction (tears, piloerection, variation of the pupillary diameter, variation of the respiratory rhythm…), walking modifications, changes in the posture, reaction to manipulation, presence of clonic or tonic movements, stereotyped or unusual behaviors, sensorial reactivity to various stimuli (auditory, visual, proprioceptive), prehension strength and moving activity.

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RESULTS:Disease,coadministration,probe dosage,sample treatment and compliance are the main factors affecting phenotyping.

结果：疾病、并用药物、探药剂量、样本处理方法、服药依从性是代谢分型的主要影响因素。

Mefthods: The serum concentrations of penicillin V potassium were determined by microbiological assay in 10 healthy male volun-teers after an oral dose of 1500 mg penicillin V potassium in crossways. Data of serum leveltime were processed with 3P87 software.

以美国进口的青霉素V钾片为标准参比制剂，研究洛阳春都制药公司研制的青霉素v钾颗粒剂相对生物利用度。10名健康受试者随机交叉口服青霉素v钾被试及参比制剂各1500mg后，采用微生物法测定不同时间血清中药物浓度，用3P87软件经微机处理药-时数据。

Recent studies showed that deamidation of Bcl-xL, an anti-apoptotic protein, regulates cellular response to DNA damage. This Bcl-xL deamidation induced by cisplatin appears to be mediated by p53 and Rb.

目前有研究显示在DNA损伤下，抗死蛋白Bcl-xL的去胺基化可调控细胞反应，而在抑癌基因p53和Rb 突变的癌细胞中也发现抗癌药物cisplatin的处理会导致Bcl-xL 的去胺基化。

"Palmar-plantar erythrodysesthesia typically presents with dysesthesia and tingling in the hands and feet, which usually appear 2 to 12 days after administration of chemotherapy," note the authors led by Domenica Lorusso, MD, from the department of oncology at Catholic University of the Sacred Heart, in Campobasso, Italy.

手掌脚掌红肿感觉异常，也称手足症候群或手至足症候群，是不舒服且相对常见的皮肤毒性反应，通常是对某些化学治疗药物；目对症候群仍所知不，为了厘清这个问题，专家于7月号癌症学志发表了一篇综论性文章，讨论如何处理这个不幸的不良反应

Objective To study the protective action of compound agent madeup with effective ingredients of Hirudo and Rhizoma chuanxiong and Folium Ginkgo in animal ischemic cerebral infarction.Methods To mix Hirudin extracts of Folium Ginkgo and Ligustrazine according2:25:5into asepsis injection,rats local cereˉbral ischemia induced by embolism of middle cerebral arterywas used as experimental model to study the efˉfects of the compound agent and positive control drug,Nimodipine and extracts of Folium Ginkgo on cerebral infarct size and neurological deficits.Disposing the experimental data with statisticsand comparing their otherness among difˉferent groups.

目的 探讨用中药水蛭、银杏、川芎的有效成分组成的复方制剂对动物局灶脑缺血的保护作用方法将水蛭素、银杏叶提取物、川芎嗪按2∶25∶5的比例制成无菌注射液，应用鼠大脑中动脉栓塞导致缺血性脑卒中的实验模型，并用生理盐水、尼莫地平和银杏提取物作对照，观察不同药物对脑缺血面积和由缺血造成的大鼠行为障碍的影响，将实验据用统计学处理并进行组间的差异性比较。

Results The incidence of adverse events in 2 475 patients selected was 0.97%,in which the incide...

结论健康育龄妇女药物流产的同时服用宫血宁后不良反应事件发生率低，持续时间短，程度轻，很快消失或好转，无需特殊处理，显示其安全性很高。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。