药物依赖

Methods: The quality of life of heroin dependent patients before and after MMT was evaluated with Quality of Life for Drug Addicts, and the difference between those improved and unimproved was analyzed with SPSS.

用《药物成瘾者生存质量评定量表》对接受美沙酮维持治疗的海洛因依赖者治疗前后的生存质量进行评价，并对生存质量改善和无改善者进行分析。

Results After more than 1 year's 99Tc-MDP therapy, 10 patients with multiple arthrosis erosion and serious malfunctioning had function recovery and arthral reformation of different extent.

结果 10例有多关节骨侵蚀严重功能障碍患者经&云克&治疗达一年以上后均见有不同程度的功能恢复和骨侵蚀的改善，显效者可以行走、旅游、生活自理或部分生活自理。3例依赖服用强的松病人可停用激素药物或减量服用（1.25mg/天）。X片示，受损的狭窄的关节间隙增宽，侵蚀的关节面得到改善，骨质疏松亦见好转。

I thank the gods for giving me such a brother, who was able by his moral character to rouse me to vigilance over myself, and who, at the same time, pleased me by his respect and affection; that my children have not been stupid nor deformed in body; that I did not make more proficiency in rhetoric, poetry, and the other studies, in which I should perhaps have been completely engaged, if I had seen that I was making progress in them; that I made haste to place those who brought me up in the station of honour, which they seemed to desire, without putting them off with hope of my doing it some time after, because they were then still young; that I knew Apollonius, Rusticus, Maximus; that I received clear and frequent impressions about living according to nature, and what kind of a life that is, so that, so far as depended on the gods, and their gifts, and help, and inspirations, nothing hindered me from forthwith living according to nature, though I still fall short of it through my own fault, and through not observing the admonitions of the gods, and, I may almost say, their direct instructions; that my body has held out so long in such a kind of life; that I never touched either Benedicta or Theodotus, and that, after having fallen into amatory passions, I was cured; and, though I was often out of humour with Rusticus, I never did anything of which I had occasion to repent; that, though it was my mother's fate to die young, she spent the last years of her life with me; that, whenever I wished to help any man in his need, or on any other occasion, I was never told that I had not the means of doing it; and that to myself the same necessity never happened, to receive anything from another; that I have such a wife, so obedient, and so affectionate, and so simple; that I had abundance of good masters for my children; and that remedies have been shown to me by dreams, both others, and against bloodspitting and giddiness...; and that, when I had an inclination to philosophy, I did not fall into the hands of any sophist, and that I did not waste my time on writers of histories, or in the resolution of syllogisms, or occupy myself about the investigation of appearances in the heavens; for all these things require the help of the gods and fortune.

我感谢神明给了我这样一个兄弟，他能以他的道德品格使我警醒，同时又以他的尊重和柔情使我愉悦；感谢神明使我的孩子既不愚笨又不残废，使我并不熟谙修辞、诗歌和别的学问，假如我看到自己在这些方面取得进展的话，本来有可能完全沉醉于其中的；我感谢神明使我迅速地给予了那些培养我的人以他们看来愿意有的荣誉，而没有延宕他们曾对我寄予的愿我以后这样做的期望（因为他们那时还是年轻的）；我感谢神明使我认识了阿珀洛尼厄斯、拉斯蒂克斯、马克西默斯，这使我对按照自然生活，对那种依赖神灵及他们的恩赐、帮助和灵感而过的生活得到了清晰而巩固的印象，没有什么东西阻止我立即按照自然生活，然而我还是因为自己的过错，因为没有注意到神灵的劝告（我几乎还可以说是他们的直接指示）而没有达到它；我的身体置于这样一种生活之外如此之久，我从未达到本尼迪克特或西奥多图斯的高度，但在陷入情欲之后，我还是被治愈了；虽然我常常达不到拉斯蒂克斯的那种气质，但还是没有做过使我悔恨的事情；虽然我母亲不能尽其天年而终，但她最后的年月是与我在一起的；在我希望帮助任何需要帮助的人的时候，或在任何别的场合，我都不感到我缺乏这样做的手段；而对我自己来说却不会有同样的需要：即需要从别人那里得到的东西；我有一个十分温顺、深情和朴实的妻子；我有许多优秀的教师来教育我的孩子；通过梦和其他办法，我发现各种药物来治疗咯血和头昏……当我有一种对哲学的爱好时，我没有落入任何诡辩家之手，没有在历史作品上，或者在三段论法的解决上浪费时间，也没有专注于探究天国的现象；而上面所有这些事情都要求有神灵和命运的帮助。

Methadone, Commonly Used as Maintenance Medication for Outpatient Treatment of Opioid Dependence, Kills Leukemia Cells and Overcomes Chemoresistance

通常用于阿片依赖患者门诊治疗的维持药物的美沙酮，可以杀死白血病细胞和克服耐药性

The clinical symptoms were markedly improved at 3 days of post-treatment,obvious difference of total mark was also appeared between the treatment group and control group.Conclusion It is suggested that inhalation of negative charge can strengthen the blood oxdation,regulate the funtions of nervous system,endosecretory and immunological system and decrease the dependence of drug against heroin.It is a better treatment for drug addicts.

通过吸入负电荷增强血液的氧化作用，对神经系统、内分泌系统及免疫系统功能有调整、改善作用，减少对戒毒药物的依赖性，是一种良好的对海洛因依赖者躯体戒断症状缓解的配合治疗方法。

Linge Pa found that these drugs can make a number of host proteins failure, but the host Buzhi Yu cause serious side effects, he said: But the virus, at least under the assumption that the current study is absolutely dependent on a particular protein, if you stop of this protein, the virus is not luck, but the host cells could be turned to other proteins, said:'Hey, can you come here?

林格帕发现，这些药物可以令许多宿主蛋白质失效，却不至于引起宿主的严重副作用，他说：可是病毒，至少在目前的研究假定下，绝对要依赖某种特定的蛋白质，如果你阻止了这种蛋白质，病毒就不走运了，但宿主细胞可以转向其他蛋白质说：'嗨，你能过来一下吗？

Marrer E, Satoh T, Johnson M M, et al. Global transcriptome analysis of the responses of a fluoroquinoloneresistant Streptococcus pneumoniae mutant and its parent to ciprofloxacin .

总结临床分离菌的研究发现，虽然多数细菌有大量排出泵，但只有少数会对临床用药产生抗性，且排出泵作用所依赖的药物和细菌不同。

He experiment results indicate that (1) The extract of Rubia Cordifolia L has the effects of anti-proliferation and inducing APO;(2) Whenadministrating with 5-fu, the extract of Rubia Cordifolia L obviously enhanced the effects of anti-proliferation and inducing APO of 5-fu;(3) The basement of molecular biology of the extract of Rubia Cordifolia L for inducing APO of MGC-803 cells is correlated with inhibiting the expression of bcl-2 of anti-apoptosis gene.

UNEL法与PCNA的免疫细胞化学法的结果：0.2、0.4、0.8、1.0mg/ml浓度的茜草提取物与2、4、8、16μg/ml浓度的5-Fu，分别诱导细胞凋亡和抑制细胞增殖，表现出浓度、时间依赖性关系，除个别浓度与个别时间之间无显著性差异（P＞0.05）外，不同浓度与不同作用时间之间均有显著性差异（P＜0.05或P＜0.01），并且两种药物联合使用时，MGC-803细胞的APO%显著提高，降低PCNA的阳性表达率（P＜0.05或P＜0.01）。

Nowadays the in silico scenario for drug design is totally dependent on structural biology and structural bioinformatics.

现在，药物设计的计算机方案完全依赖于结构生物学和结构生物信息学。

Objective: Using the outer-cell recording to observe the morphine responses of nucleus accumbens and ventral subiculum, and explore the function of them in the process of drug-dependence.

目的：用胞外记录的方法分别观察伏隔核和海马腹侧下托对吗啡的反应性，探讨其在药物心理依赖形成过程中所处的地位。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。