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Producing stains. Methods The drug susceptibility of 42 AmpC and ESBLs producing Klebsiella were detected by Kirby?Bauer motheds, Vitek 60 and Vitek 32 method. And the results were compared with those of 24 Klebsiella producing AmpC but nonproducing ESBLs and those of 138 Klebsiella producing ESBLs but nonproducing AmpC. The genotypes of AmpC were identified by PCR. Results All AmpC?

采用Vitek 60型和Vitek 32型、纸片扩散法测定42株产AmpC酶同时产ESBLs克雷伯菌的敏结果,并与24株产AmpC酶但不产ESBLs克雷伯菌和138株不产AmpC酶但产ESBLs的克雷伯菌敏结果对比分析;采用PCR分析产AmpC酶但不产ESBLs肺炎克雷伯菌的AmpC基因型。

Methods Targeting the most common mutation types at codon 526 and codon 531 of Rifampiein Resistance Determining Region of rpoB gene from Mycobacterium tuberculosis ,labeled probes (526CAC, 526TAC, 531TCG and 531TTG) were designed to detect 38 Rifampin-resistant clinical isolates with known RRDR sequence, 24 Rifampin-sensitive clinical isolates with wild type sequence of RRDR and 5 nontuberculous mycobacteria isolates, then a method using real-time PCR was established.

方法针对结核分枝杆菌rpoB基因利福平耐决定区(Rifampicin Resistance Determining Region,RRDR)526密码子和531密码子常见的突变形式设计探针(526CAC,526TAC,531TCG和531TTG),应用已知rpoB基因RRDR区序列的38株利福平耐临床分离株和24株利福平敏感临床分离株以及5株非结核分枝杆菌菌株建立荧光定量PCR检测基因突变的方法。

RESULTS:Using nubilous inhalation or intragastric administration,artesunate significantly inhibited the guinea-pig model asthma in a dose-dependent manner.Its ED50 were (99.95±7.69)mg.L-1(n=4) and (15.64±1.25)mg.kg-1.d-1(n=4) respectively.

结果:雾化或灌胃给,青蒿琥酯均对源性哮喘呈现剂量依赖性明显的抑制作用,其半数有效剂量(ED50)分别为(99.95±7.69)mg.L-1(n=4)和(15.64±1.25)mg.kg-1.d-1(n=4),其抑制作用与给的剂量之间呈良好线性关系。

The elimination half-life t(subscript β1/2 was 161.10h, 333.21 h and 611.26h, respectively, and the total body clearance was 27.4mL/, 16.8g/ and 18.0g/, respectively. The metabolite ciprofloxacin concentration-time profiles of the plasma, muscle and liver presented similar trend. The multi- peak phenomenon were observed in the plasma, muscle and liver, but the first peak time was 24h, 24h and 12h, respectively. The peak residue of metabolite ciprofloxacin was in liver, muscle and plasma, ordinally. The eliminating rate of ciprofloxacin from muscle and liver was very low.

代谢物环丙沙星在鳗鲡血浆、肌肉和肝脏中物水平的变化趋势与恩诺沙星基本相似,呈现出多峰现象,但3种组织中环丙沙星出现第一个峰时间分别为给后第24小时、24小时和12小时,3种组织中环丙沙星峰值水平肝脏中最高、肌肉中次之、血浆中最低,环丙沙星在肌肉和肝脏中的消除速率比较缓慢。

Bisexual flowers: stamens 1 or 3, inserted on 1 side of ovary; filaments inconspicuous; connectives conspicuous, if stamens 3, connectives connate at base or free; anthers 1- or 2-loculed, longitudinally dehiscent; pistil 1, 1-carpelled; ovary inferior, 1-loculed; ovule 1, pendulous, orthotropous; style short or absent.

两性花:雄蕊1或者3,在子房的1侧着生;花丝不显著;隔显著,如果雄蕊3,隔在基部合生或离生;室花1或2,纵向开裂;雌蕊1,1心皮;子房下位,1室;胚珠1,下垂,;花柱短或无。

Osmotically controlled oral drug delivery systemsutilize osmotic pressure for controlled delivery of active agents.

中文摘要:口服渗透泵控释给系统作为目前最理想的控释技术之一,具有释均匀恒速、不受体内环境影响、适应范围广等特点。

RESULTS: The C_ max of OXY transdermal gel and oral tablets in bladder are approximately 800 and 70 times higher than those in plasma.

结果:凝胶剂外用给奥昔布宁膀胱组织浓度为血浆的800倍,而口服给为70倍。

Connective The parenchymatous tissue that joins the two lobes of the anther and contains the vascular strand.

隔:花左右两侧花粉囊之间由薄壁细胞构成的基本组织,隔中的维管束与花丝维管束相连。

Results On the 7th day after irradiation compared with the negative control group number of CFU-S, BMNC and spleen index of mice have received the treatment with polysaccharides from parmelia tinctorium for three days before to irradiation increased markedly. The DNA repair of medicine group increased significantly and the residual damage decreased gradually.

结果 照射前连续给3 d,照后第7天受照小鼠的BMNC、CFU-S和脾指数与对照组相比有明显的增高;SCGE中各项指标显示,给组的DNA损伤的修复明显增加,呈明显的量-效关系。

The microcirculation disturbance in mice was brought by rapid injection of adrenaline.The micro vascular diameter,the blood flow speed and micrangium crossing net patefaction number in auricle of mice at normal condition and in the 10,20,30 min after injection of adrenaline were observed by microcirculation microscope with analytical system.

连续给4 d,末次给30 min时将小鼠固定于微循环观测分析系统显微镜下,观测小鼠正常及腹腔注射盐酸肾上腺素(1 mg·kg-1)10、20和30 min时小鼠耳廓微血管的管径、血流速度及毛细血管交叉网开放数目。

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