药

Objective To study the relationship between the expression of mtrF gene and high-level multiple resistant Neisseria gonorrhoea.

目的 探讨mtrF基因在多重耐药淋球菌中的表达及其与高水平多重耐药淋球菌的关系。

ABSTRACT: Objective To study the relationship between the expression of mtrF gene and high?level multiple resistant Neisseria gonorrhoea.

目的 探讨mtrF基因在多重耐药淋球菌中的表达及其与高水平多重耐药淋球菌的关系。

Objective: Determination the neurotension content through the hypertension patients acupuncture treatment union pharmacotherapy around,further discusses the acupuncture treatment union pharmacotherapy to treat the action mechanism ofhypertension.

目的：通过测定高血压患者针药结合治疗前后神经降压素的含量，进一步探讨针药结合治疗高血压病的作用机理。方法：将75例患者按入院先后顺序随机分为2组：针刺加药物组45例及药物组30例，观察治疗前后神经降压素的变化情况。

METHODS To count rabbit nictation times,short-time multiple eye drops irritation(once per 15 minute for continuously 2 hours) and long-time eye drops irritation(5 times per day for continuously 4 weeks).

方法计数兔眨眼次数、短期多次给药眼刺激(1次/15min，连续滴眼2h)和长期给药眼刺激(5次/日，连续滴眼4周)作用。

The results indicate that there is a change of burning rate pressure exponential of nitramine propellants, and the content of NGu can adjust the combustion rules Of nitramine propellants under low pressure.

结果发现：硝胺发射药在测试压力范围内有燃速压力曲线转折现象，并且NGu对低压下硝胺发射药燃烧规律有很好的调节作用。

The results indicate that there is a change of burning rate pressure exponential of nitramine propellants,and the content of NGu can adjust the combustion rules of nitramine propellants under l.

结果发现：硝胺发射药在测试压力范围内有燃速压力曲线转折现象，并且NGu对低压下硝胺发射药燃烧规律有很好的调节作用。

In this thesis, the principle that the charge technique of coated nitramine and energy increased propellant with low temperature sensitivity improves the muzzle velocity and decreases ballistic temperature coefficient is studied.

本文研究了低温感硝胺及增能发射药装药技术提高火炮初速和降低弹道温度系数的原理及其对膛压和初速变化规律的影响，阐述了提高低温感。。。

Accroding to the principle of low temperature sensitivity charge, the application test of LTSC of nitramine propellant in the large middle caliber gun was analysed.

从低温感发射药的基本原理出发，对低温感硝胺发射药在中大口径火炮上的应用试验进行了分析研究。

The combustion properties of low temperature sensitivity coated nitroamine propellant had been studied using granule powder as concussion gas source in closed vessel.

采用小粒药作为冲击药在密闭爆发器中研究了低温感高能硝胺包覆火药的燃烧特性。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。