药

We selected mecA gene and femA factor asβ-lactam antibiotic-resistant genes, ermA, ermC, msrAgene as macrolides-lincosamids antibiotic-resistant genes, norA, grlA, gyrA, gene as Quinolonesantibiotic-resistant genes, and tetM gene as Tetracycline antibiotic-resistant genes on the basis of the latestresearch. We designed primers with GenBank enunciable gene sequence, cloned the drug resistantgenes, and sequenced these genes.

根据国内外最新文献报道，筛选出对β-内酰胺类抗生素耐药的mecA基因及辅助因子femA；对大环内酯类及林可霉素类抗生素耐药的ermA、ermC、msrA基因，对喹诺酮类抗菌药物耐药的norA、grlA和gyrA基因及对四环素类抗生素耐药的tetM基因作为拟选的主要耐药基因，分别设计PCR扩增的特异性引物，进行克隆。

Drug sensitive test and three-dimensional test220 strains of Pa were isolated from hospitalized patients between 2003 and 2007. K-B method was used to tested the susceptibility of 10 different antibiotics. IRPa was screened by testing the minimal inhibitory concentration of imipemem by using agar diluiion method.The susceptibility of these IRPa to the antibiotics was analysised. Three-dimensional test was used to identify the different kinds of beta lactamases from 220 strains of Pa.2.Carbarpenems hydrolytic enzyme genes and oprD2 gene were detectedamong the selected IRPa strains, PCR method was performed to detect carbapenemase genes which included GES、KPC、SPM、VIM、IMP、GIM gene and the oprD2 gene;Multiplex PCR were used to detect OXA genes and plasmid-mediated AmpC beta lactamase genes; The expression of the chromosomal AmpC beta lactamases and oprD2 genes in IRPa strains were analyzed by Real-time PCR.3.Identification and characterization of integronsIntegrase gene was detected by PCR, and the classification of integrons was performed by using restriction fragment length polymorphism.PCR was performed to detect the qacE△1-sull gene,and the gene cassetes which are located at variable region of integrons in the strains were detected to be positive.

方法1、药敏实验和三维实验收集2003～2007年临床分离的220株Pa，对这些菌株采用K-B法测定10种临床常用抗生素的药敏情况，同时采用琼脂稀释法检测亚胺培南的最低抑菌浓度(Minimal inhibitory concentration，MIC)，筛选出对亚胺培南耐药的铜绿假单胞菌，并分析其对其它抗生素的药物敏感率；采用三维实验的方法分析220株Pa产β内酰胺酶的类型。2、碳青霉烯类水解酶和oprD2蛋白的检测针对鉴定的IRPa菌株，采用普通PCR方法检测具有碳青霉烯水解作用的β内酰胺酶耐药基因(GES、KPC、SPM、VIM、IMP、GIM基因)和oprD2基因，采用多重PCR的方法检测OXA型基因和质粒携带的AmpC酶基因，用荧光定量RT-PCR方法检测oprD2蛋白基因表达情况；同时对产AmpC酶的Pa(25株，含IMP耐药和敏感株)用RT-PCR方法检测AmpC酶基因的表达量情况。3。

The contents of mineral elements, like Fe, in LMTCMs were higher than that of nor-LMTCM. The result of analysis of mineral element of 14 LMTCMs by ICP-MS method also showed the content of Fe have something to do with lung meridian tropism effects. The result of the study of platycodon radix approved the laws too. These laws were used to predict if the marine medicines have the lung meridian tropism effects.2. The Compatibility laws of Medicines and their chemical composition in LSP were studied by mining the data of the constituent herbs and their chemical composition. The results showed that the most constituent medicines of lung system prescriptions have lung meridian tropism. Radix glycyrrhizae, herba ephedrae, semen armeniacae amarum, fructus schisandrae Chinese and their compatibility are common in lung system prescriptions. Terpene, alkaloid, steroid, and flavanoid compounds and their compatibility are common in lung system prescriptions.3. The marine phycophyta medicines of LSP were studied by the same method.

对比归肺经中药及肺系方剂主要化学成分构成，萜类、生物碱、甾体类成分可能是归肺经中药及肺系方剂的主要药效成分；结合君臣佐使药的化学成分构成特点及肺系方剂组成中药的归经构成情况，肺系方剂组方设计应该考虑以下几个方面：一、优先考虑归肺经中药，在应用不归肺经中药时要配伍归肺经中药；二、组方时应考虑含萜类、甾体及生物碱类化合物的中药；治疗肺咳病及咳嗽症状时可以考虑含萜类化合物的中药，治疗气喘症状时可以考虑含生物碱类化合物的中药；三、在确定组方中药或化学成分配伍关系时，君药多考虑含生物碱、黄酮类化合物的中药；臣药、佐药可以考虑含萜类及甾体类化合物中药；使药可以考虑含萜类、甾体类及黄酮类化合物的中药。

The explosively formed projectile with fins for a cover charge structure by LS-DYNA software which four covers were conglutinated on the liner was studied by three-dimensional numerical simulation. The mechanism of forming EFP with fins was discussed based on the curves of velocity and pressure vs time of the liners. A contrastive analysis was carried out on the three kinds of liners which include big-cone shaped liner, imperfect-sphere shaped liner and arc-cone shaped liner.

采用LS-DYNA对在药型罩上粘附隔板结构形成带尾翼型爆炸成型弹丸(explosively formed projectile，EFP)进行三维数值模拟，从药型罩微元压跨速度和压力的角度初步探讨了形成尾翼型EFP的机理，对同一直径的大锥角型、球缺型和弧锥结合型药型罩形成的尾翼型EFP进行了对比分析，三种结构药型罩均能形成较为明显的尾翼，其中大锥角型药型罩得到的EFP速度最高。

The loading method and the quantity of linker had greater effect on in-vitro release curve. Release curve of incubation-absorption and entrapping method had two phases—quick release phase and slow release phase. And the first phase lasted about one hour and released 70% drug.

载药方法和交联剂用量对释药曲线有显著影响，吸附法和包埋法制备的载药DSMs的释药曲线明显分为快速释药阶段和缓慢释药阶段，第一阶段持续约1 h，释放药物的70%左右。

Huajun Weighing Weighing accessories product specifications and the full range, is now the main product specifications in a variety of scales, Bench (100 bench, 500 bench, 1000 Scales), of the Pan Cheng, electronic scale (including electronic scales, electronic hand-held scales , Etc.), drug scales (10 g-scale, 100 g-scale, 250 g-scale, 500 g-scale), food scales, weighing one side, kitchen scales, scales mechanical human health, human health electronic scales, weights (including lock-Fa Code, weight balance, flat-weight, by Pretoria-based weight), Decheng accessories, loadometer accessories, and the value of accessories, and so on.

华钧衡器及衡器配件产品规格品种齐全，现主要产品有各种规格案秤、台秤（100型台秤、500型台秤、1000型台秤）、度盘秤、电子秤（包括电子台秤、电子手提秤等）、药秤（10g药秤、100g药秤、250g药秤、500g药秤）、食品秤、单面秤、厨房秤、机械人体健康秤、电子人体健康秤、砝码（包括锁型砝码、天平砝码、平头砝码、增陀型砝码）、地秤配件、地磅配件、地中衡配件，等等。

According to the working principle and process of regenerative injection of the regenerative liquid propellant auxiliary chamber gun, this thesis analysis the process of regenerative injection cycle and puts forward the structure of the auxiliary chamber.

本文从再生式液体发射药辅助药室火炮的再生喷射原理和工作过程出发，分析了辅助药室火炮再生喷射循环过程，提出了再生式液体发射药辅助药室的结构。

According to the character of the B/KNO3 fire composition,three igniters with different charging structure are comparative tested and analyzed,and aimed at the parameters of the electric igniter,calculation and design are made for the ignition charge,intermediate charge and igniter charge ring,then the charging structure of electric igniter for a certain solid rocket motor is determined.

基于B/KNO3点火药的特性，采用三种不同药型的点火具装药进行对比试验和分析，并针对电点火具的性能指标要求，分别对传火药、过渡药、点火药环进行了计算和设计，确定了适用于某固体火箭发动机用电点火具装药的药型。

The dosage is determined by pH control approach, which does not require a routine jar test. This method can simultaneously determine the optimal pH and economical dosage for oxide-CMP wastewater. The coagulant can be added directly into the raw water without the pH adjusting at first. According to this method, the coagulant acts like a titrant and the pH of the oxide-CMP wastewater is monitored. The optimal dosage is the one that corresponds to a specific pH.

本论文主要以「pH控制法」来决定线上加药剂量值，其与传统瓶杯试验不同的是，其加药逻辑可直接对线上加药进行控制且毋须定期确认参数。pH控制法视混凝剂为酸滴定药剂，直接对进流之氧化层研磨废水进行加药，及至特定pH时，加药停止，此时之加药量即为电性中和去稳之控制点，远较过量加药法经济。

Methods PCR screening and DNA sequence were used to determine the drug resistance genes associated with class I integron in 4 clinical strains of P.aeruginosa. The resistance genes were located by conjugated transfer experiments and the conjugations were studied by PCR method.

整合子通过整合酶从环境中捕获耐药基因盒，并将耐药基因盒组装在一起，形成巨大的耐药基因多基因座；同时整合子及耐药基因盒可借助转化、转导及接合等方式在细菌中转移，使耐药基因广泛传播。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。