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The compounds are represented by the structural Formula 1, Chemical formula should be inderted here as it appears on the abstract in paper form. a prodrug thereof, or any pharmaceutically acceptable salt, solvate, isomer or racemic mixture of the compound or said prodrug wherein R1 is heteroaryl, N-arylaminocarbonyl, N-heteroarylaminocarbonyl, benzimidazolyl or benzothiazolyl; R15 is present or not and if present is H, aryl, alkyl, arylalky or heteroarylalkyl; A is aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene or heterocycloalkyl wherein said aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene and heterocycloalkyl moieties may be substituted or unsubstituted; and B, L, X and R18 are defined herein.

所述化合物用结构式1表示,包括其前或所述化合物或所述前的任何学上可接受的盐、溶剂合物、异构体或外消旋混合物,其中R 1 为杂芳基、N-芳基氨基羰基、N-杂芳基氨基羰基、苯并咪唑基或苯并噻唑基;R 15 存在或不存在,如果存在,则为H、芳基、烷基、芳基烷基或杂芳基烷基;A为芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基或杂环烷基,其中所述芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基和杂环烷基部分可被取代或未被取代;B、L、X和R 18 如说明书所定义。

Moreover, the paper describes the design of several kinds of popular grains , for instance: monotramonous grain and starlike grain, and obtains computer program.

本论文还论述了几种常用柱的设计,如单孔管状、星孔装等的传统设计理论,并将设计过程进行了计算机实现,为一般常见柱的设计提供了更方便的途径。

Objective To establish Hela/MMC cell subline of human cervical cancer and study the mechanism of its drug-resistance.

提 要:目的建立宫颈癌Hela/MMC耐细胞亚系,并探讨其耐机制。

Objective To investigate biological characters of a multidrug resistant associated protein overexpression subline of a bladder carcinoma cell line.

目的 观察稳定表达多耐受相关蛋白(multidrugresistance relatedprotein ,MRP)的膀胱癌细胞有关多耐受(multidrugresistance ,MDR)的生物学特征。

Objective To investigate MRP expression and multidrug resistance phenotype of a bladder carcinoma subline transfected with the full length MRP cDNA.

目的 观察膀胱癌细胞多耐受相关蛋白的表达情况及多耐受表型。

METHODS Using digoxin-labelled mdr 1 cDNA probe,we detected mdr 1 mRNA in multidrug-resistant subline of human lung cancer cell lines,LC-...

结论mdr1基因表达是人肺腺癌多细胞系LC-3/DDP产生耐性的相关因素。

Fold resistance to the antimetabolites. the subline, however, was not resistant to alkylating agents,platinum compounds, and other naturally-derived antineoplastics.

该细胞株对抗代谢产生6.70倍的耐,但对多种其他天然来源的抗肿瘤物、烷化剂以及铂类化合物则缺乏交叉耐性。

Injection and sublingual therapy are common ways to administer this relief.

注射和舌下给治疗是缓解变态反应的常规给途径。

In addition,due to the specific actions of CMM on intestinal diseases,oral colon targeting drug delivery system is considered substantials for TODDSs of CMM.

此外,由于中对肠道疾病的特殊作用,口服结肠靶向给系统也是中靶向给的一个重要部分。

The degradation rate of SF-PGA-FU andSF-PLA-FU were declined by the introduction of sulfadiazine and 5-fluorouracil to prodrugsterminal.

由于5-FU和SF的封端作用,前的降解速度较高分子载体有所降低,从而提高了前的稳定性。

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推荐网络例句

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。