药

METHODS: We randomized 42 healthy parturients in early laborto receive 0.1% ropivacaine + fentanyl 2 g/mL eithervia PCEA+BCI (n = 21,bolus 5 mL, lockout 10 min, basal infusion5 mL/h) or via PCEA+AMB (n = 21, patient-activated bolus of5 mL, lockout 10 min, basal automated boluses of 5 mL/h [omittedif a patient-activated bolus was successfully administered inthe last 1 h]) after successful induction of combined spinalepidural analgesia.

我们将42名处于早期产程的健康娠妇女在成接受腰硬联合镇痛后，随机分为两组，一组接受 PCEA+BCI (n = 21，单次给药5ml ，锁定时间 10分钟，背景剂量5 mL/h)，另一组接受 PCEA+AMB (n = 21，患者自控单次给药5 mL，锁定时间 10 分钟，背景剂量自单次给药5ml/h)，两组均给予0.1%的罗哌卡因+太尼2 g/mL 。

Company specializing in packaging machinery, pharmaceutical machinery, food machinery leading product XWZ-90 drug version of cartoning machines, XWZ-90P medicine bottle cartoning machine, XWZ-90G Ointment (injection cartoning machine, XWZ-100 horizontal cartoning machine, XWZ-100P drug bottling machine, XWZ-120 cartoning machine, XWZ-200 consecutive high-speed cartoning machine series, scientific research, development, production, sales and service into one.

公司专业从事包装机械，制药机械，食品机械（主导产品XWZ-90药版装盒机，XWZ-90P药瓶装盒机，XWZ-90G软膏装盒机，XWZ-100卧式装盒机，XWZ-100P药瓶装合机，XWZ-120装盒机，XWZ-200连续式高速装盒机系列），集科研，开发，生产，销售，服务为一体。

Methods: One hundred and sixty SD rats were randomly divided into four groups （40 in each group）, and orally given the medicine with doses of 50, 25, or 12.5 g/kg of crude drug, or with bean oil of 0.5％CMC-Na daily for 26 weeks.The physical status （body weight,growth rate and appetite）, hematological parameters, blood biochemistry, blood cotting, organ index, and tissue pathological changes of rats were checked in the 13th week,and 26th week of the administration and in four weeks after the stop of the administration.

160只SD大鼠，随机分为高、中、低剂量组及空白对照组，雌雄各半，每日灌胃1次，连续给药26周，观察大鼠的一般状况、体重、摄食量和给药13、26周及停药后4周大鼠的血液学、血液生化学、凝血功能、脏器系数、解剖学及病理组织学改变的情况。

The physical status （body weight,growth rate and appetite）, hematological parameters, blood biochemistry, blood cotting, organ index, and tissue pathological changes of rats were checked in the 13th week,and 26th week of the administration and in four weeks after the stop of the administration.

160只SD大鼠，随机分为高、中、低剂量组及空白对照组，雌雄各半，每日灌胃1次，连续给药26周，观察大鼠的一般状况、体重、摄食量和给药13、26周及停药后4周大鼠的血液学、血液生化学、凝血功能、脏器系数、解剖学及病理组织学改变的情况。

Finally, the properties of the drug-loaded SN have been evaluated with the help of UV spectrophotometer, and with the small molecular and water insoluble drug-sulpiride as a model drug. It is found that the entrapping efficiency of drug-loaded SN in entrapping method can amount to 96.87% and that in adsorption method is 87.63%, which show that the loading mechanism of SN is mainly adsorptive mechanism.

最后，利用紫外分光光度计，以疏水性小分子药物舒必利为模型药物，对所制备的淀粉纳米粒的载药性能进行了评价，发现淀粉纳米粒包埋载药的包封率可达到96.87％，吸附载药的包封率达到87.63％，淀粉纳米粒对舒必利的载药机理主要是吸附机理。

Methods: NG108-15 cells were cultured in vitro at 37℃in a humidified atmospherecontaining 5％CO_2. Aβ_(25～35) fragment was dissolved with deionized distilledwater and aged for 4 days at 37℃. The cells were exposured to 5μmol/LAβ_(25～35) for 24h to establish the cell model. Twelve rabbits were divided intotwo groups at random, and garaged with MWD or physiological saline controlrespectively for 7 days to collect two kinds of cerebrospinal fluid, theyare CSF from rabbits treated with MWD and CSF from rabbits treated withphysiological saline.

NG108-15细胞在37℃、体积分数为5％的CO_2培养箱中培养，Aβ_(25～35)溶解于双蒸水中，置于37℃培养箱中老化4d，使其寡聚，毒性增强，细胞被置于浓度为5μmol／L的Aβ_(25～35)中作用24h，建立起AD细胞模型。12只清洁级大耳白家兔购于华中科技大学同济医学院动物中心，将其随机分成两组，分别给与等量的加味温胆汤和生理盐水灌胃7d，末次给药后1h内用水合氯醛将给药组白兔麻醉，1.2ml／kg，无菌条件下用7号注射针头从枕骨大孔处垂直进针，抽取清亮含药脑脊液。

The mtrD expression had no significant change in highlevel multiple resistant group or intermediated resistant group. Conclusion The mtrF expression is higher in highlevel multiple resistant group than in other two groups, and mtrF gene may play an important role in mediating highlevel multiple resistance in Neisseria gonorrhoeae.

mtrF基因在高水平多重耐药组中表达均高于敏感组和低中等水平多重耐药组，表明其在介导淋球菌产生高水平多重耐药过程中可能发挥着十分重要的作用。

Major advantages of transdermal drug delivery system include avoiding of drug degradation in hepatic and gastrointestinal,predetermining release rate and blood drug level,reducing administration frequency and adverse reactions,and increasing patient compliance.

透皮给药系统可有效避免肝脏首过效应及胃肠道降解，调控释药速率和血药浓度，降低不良反应及用药频率，提高患者顺应性。

The serums of both groups were collected before the administration, in the week 1, 2, 3 and 4 after the last injection.

并在给药前1天、第2、4、8、12、15、18和20次给药时及停药后第1、2、3和4周采血。

Shun Ho by agents NIKKISO EIKO quantitative pump, BB for the main models, mainly used in water treatment plus drugs, plus drugs, such as manufacturing process, due to stable performance, the effect of the fine, Platts clients affirmation for satisfy domestic customers for various types of pumping requirements and provide a full range of services, one after another deputy Japan SEIKOW acid pumped magnetic and corrosion-resistant blower and other new products, but also Deputy German technical cooperation with Taiwan SERA automatic foam polymer drug equipment, Germany Verder pump hose pneumatic double diaphragm pump, stainless steel magnetic pump, Italy nova / SIDEX uniaxial screw pump, CSFinox pneumatic piston pump food-grade health-pumped, the United States standard barrel with electric pneumatic pump, the introduction of a wider range of new products, provide customers more choices.

顺贺所代理的NIKKISO EIKO 定量泵，BB为主力机种，主要运用于水处理加药，制程加药等，由于性能稳定，效果优良，普获客户肯定，为了满足国内客户对于各类型泵浦需求及提供全方位的服务，陆续代理日本SEIKOW耐酸碱磁力泵浦及耐腐蚀送风机等新产品，同时也代理德国SERA与台湾技术合作高分子自动泡药设备，德国VERDER软管式泵气动双隔膜泵浦，不锈钢磁力泵浦，意大利新星/SIDEX单轴螺旋泵，CSFinox气动柱塞式泵浦食品级卫生泵浦，美国标准电动气动桶用泵浦，引进更广泛的新产品，提供客户更多的选择。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。