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The interaction between diammonium glycyrrhizinate and bovine serum albumin was studied in physicological solution by spectroscopic methods including fluorescence spectra and UV visible absorption spectra. Synchronous fluorescence and three-dimensional fluorescence spectra were used to investigate the conformation change of bovine serum albumin due to the addition of diammonium glycyrrhizinate.

在模拟人体生理条件下,用常规荧光光谱和紫外-可见吸收光谱研究甘草酸二铵和牛血清白蛋白的相互作用机制,并利用同步荧光光谱和三维荧光光谱研究了药物对牛血清白蛋白构象的影响。

The back extraction of Am 3+,Pu,UO 2+ 2 and TcO - 4 with high concentration nitric acid, oxalic acid, sodium carbonate, ammonium carbonate respectively from different 30% TRPO/kerosene systems are studied.

研究了硝酸、草酸、碳酸钠和碳酸铵对 4种不同来源的TRPO/煤油中Am3 +,Pu ,UO2 2 +和TcO-4的反萃,观察了碳酸钠溶液反萃铀时的乳化现象,比较了上述 4种TRPO的红外光谱、裂解色谱。

In this paper, we successfully developed a novel approach for the preparation of N-doped TiO2 photocatalysts by calcining ammonium titanium oxalate at different temperatures.

这篇文章报道了利用草酸氧钛铵(NH42TiO(C2O4)2在不同温度的控制分解来制备N掺杂TiO2光催化剂的新方法。

Photodegradation of a basic anion dye-fuchsin basic by using ammonium ferric oxalate and H2O2 as a mediator in an aqueous medium was investigated.

研究了用UV/草酸高铁铵/H2O2体系光降解一种碱性阳离子染料-碱性品红。

The experimental results indicates that the optimum pH range was 1.60~2.20, and the optimum H2O2 concentration was 10.0 mmol/L. The degradation ratio increased with the increasing concentration of ammonium ferric oxalate in the range from 0.1 to 1.0 mmol/L, but no significant increase in degradation ratio was observed when the concentration was above 1.0 mmol/L. When the concentration of fuchsin basic increased, the degradation ratio dropped, while the concentration of degraded fuchsin basic rised. When the concentration of fuchsin basic was low, the degradation followed first-order kinetics, but when it was high, the degradation could be fitted by zero-order kinetics. The absorbtion of fuchsin basic at 543 nm disappeared quickly, while the absorbtion of intermediates formed during the course of fuchsin basic dagradation at 298 nm vanished slowly.

试验结果表明:碱性品红降解的最佳初始pH为1.60~2.20,最佳初始H2O2浓度为10.0mmol/L;草酸高铁铵的浓度在0.1~1.0mmol/L时,碱性品红的降解率随浓度的增大而增大;高于1.0mmol/L时,则降解率相差不大;碱性品红的初始浓度增大,降解率减小,而实际降解的浓度则增加;碱性品红的浓度在低和高时,降解动力学过程不一致;随降解的进行,碱性品红在可见光区的吸收峰迅速消失,而降解过程中形成的中间产物吸收峰却消失很慢。

The therapy of protection of liver function is very necessary: diammonium glycyrrhizinate can recover the non-specific damage of liver cells, Fufangdanshen can improve the microcirculation of liver, and tiopronin and reduced glutathione has the unique function to recover liver damage caused by fat invasion. Of 168 cases, 60 cases (35.7%) show exacerbation of liver function after using fat-reducing drugs for 1-2 weeks. Of 41 cases (male 36 and female 5) with the complication DM2, 58.5%(24/41) of cases also show exacerbation of liver function after using sugar-reducing drugs.

保肝治疗非常必要,甘草酸二铵有修复非特异性的肝细胞损伤的作用,复方丹参可以改善肝脏微循环;硫普罗宁或还原性谷胱甘肽,对于脂肪肝之由于脂肪浸润引起的肝细胞损伤的修复有独到的作用。168例中有60例(35.7%)因用降脂药物1~2周出现肝功能异常的加重;合并2型糖尿病的41例(男36例,女5例)患者中有58.5%(24/41)的人用降糖药物后也出现肝功能异常的加重。

Diet-controlling and movement for weight-reducing are the utmost method for the therapy of NAFL. The therapy of protection of liver function is very necessary: diammonium glycyrrhizinate and Fufangdanshen as basic drugs and tiopronin as main drugs. We should be prudent to use sugar-reducing drugs. And we shouldn't advocate to use fat-reducing drugs routinely.

控制饮食和运动以减肥是治疗NAFL的首要措施;保肝治疗非常必要,甘草酸二铵和复方丹参作为基本用药,硫普罗宁或还原性谷胱甘肽作为必选药物;慎用降糖药物,不提倡常规使用降脂药物。

Objective To establish HPLC-UV method for determination of glycyrrhizin acid in compound nasal spray of glycyrrhizin and flower flos magnoliae,the chief active ingredient of formulation,glycyrrhizin acid,and to observethe therapeutic effect of this formulation on guinea pig's hypersensitive rhinitis.Methods A compound nasal spray formulation was prepared using extracts of glycyrrhizin and measured by HPLC-UV method.Mobile phase conˉsisted of methanol,0.2mol/L ammonium acetate and glacial acetic acid(67:33:1,v/v),analytical column was Zorbax ODS C 18 and wavelength250nm.

目的 建立测定复方甘草和辛夷喷雾剂含量的方法并观察该制剂对豚鼠超敏性鼻炎的疗效方法以甘草提取的甘草甜素和辛夷花蒸馏提取液主药制备成鼻用喷雾剂,用反相高效液相色谱法测定制剂中甘草酸含量,检测波长为250nm,Zorbax ODS C 18 分析柱,流动相为甲醇:0.2mol/L醋酸铵:冰醋酸(67:33:1)。

Table 2 Effects of nitrate/ammonium ratio in solution culture on the accumulation of oxalates of different forms in leaves

表2 硝态氮/铵态氮比例对叶片、叶柄和地上部不同形态草酸累积量的影响 mg/ plant, FW

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