草酰胺

Field experiments demonstrated that efficacy of 30% dichlorvos and omethoate for Caloptilia dentata was over 80%, for Drosicha corpulenta was 95.9% and Psylla willieti 96.4%. For Parathrene tabanifomis, Anoplophora glabripennis, Apriona swainsoni and Panonychus ulmi also gained perfected efficiency, and injection dosage of 2.0ml/cm φ for Myzus persicae obtained 100%result, for Eriococcus lagerostioemiae which damage Punica gianatum the result was 92.96%. In all, the efficiency of 30% diohlorvos · omethoate control of most pests was better than bisultap, decis, acephate, nicotine and avermectin, etc.

田间防效结果表明30%敌畏·氧乐对元宝枫细蛾的防治效果可以达到80%以上，对草履蚧和槐木虱防效分别大于95.9%和96.4%，对白杨透翅蛾幼虫、危害新疆杨和合作杨的光肩星天牛幼虫、危害国槐的锈色粒肩天牛幼虫、危害苹果的榆全爪螨等可达到理想防效，当施药剂量为2.0 ml/cmφ时对桃蚜的防效达100%，对危害石榴的紫薇绒蚧防效可达92.96%以上。30%敌畏·氧乐对大多数害虫的控制作用优于杀虫双、敌杀死、乙酰甲胺磷、烟碱和阿维菌素等。

ObjectiveTo establish a determination method of the content of N-trans-feruloyl tyramine in Alternanthera philoxerodes.

目的建立空心莲子草中穆坪马兜铃酰胺的含量测定方法。

RESULTS: Sixteen compounds, ursolic acid (1), indole-3-carboxaldehyde (2), indole-3-carboxylic acid (3), p-coumaric acid (4), azelaic acid (5), N-trans-feruloyl tyramine (6), blumenol A (7), 2-hydroxy-3-methylanthraquinone (8), rubiadin l-methyl ether (9), rubiadin (10), quercetin (11), luteolin (12), chrysoeriol 6-C-β-boivinopyranosyl-7-O-β-glucopyranoside (13), alternanthin (14), stigmasta-5, 22-dien-3β-ol (15), and α-spinasterol (16) were obtained from the EtOAc extract of Alternanthera philoxeroides.

结果：得到并鉴定了16个化合物，分别为乌苏酸(1)、吲哚-3-甲醛(2)、吲哚-3-甲酸(3)、对-香豆酸(4)、壬二酸(5)、N-反式阿魏酰基酪胺(6)、布卢姆醇A(7)、2-羟基-3-甲基蒽醌(8)、甲基异茜草素-1-甲醚(9)、甲基异茜草素(10)、槲皮素(11)、木犀草素(12)、柯伊利素-6-C-β-波伊文糖基-7-O-β-吡喃葡萄糖苷(13)、莲子草素(14)、豆甾醇(15)和α-菠甾醇(16)。

Firstly, 3-ethylthiobutanal was prepared from crotonaldehyde reacting with ethanehiol in triethylamine with high yield. Secondly, methyl acetoacetate was converted to 6-ethylthiohept-3-en-2-one by three steps via hydrolysis, condensation with 3-ethyltio-butanal and dehydration, then 6-ethylthiohept-3-en-2-one was cycloco ndensed with dimethyl malonate by Michael addition and Claisen condensation, followed by saponification and decarboxylation to give the intermediate of 5-(2-ethylthiopropyl)-cyclohexane-1,3-dione.

首先，以巴豆醛与乙硫醇为原料，在三乙胺的催化作用下高收率制得3-乙硫基丁醛；然后从乙酰乙酸甲酯出发，通过碱水解、与3-乙硫基丁醛缩合、脱水三步反应合成6-乙硫基-3-烯-2-庚酮，接着6-乙硫基-3-烯-2-庚酮与丙二酸二甲酯通过Michael加成和Claisen缩合成环，再通过皂化和脱羧反应生成中间体5-[2-丙基]-1，3-环己二酮；再与丙酸酐反应丙酰化，最后与0-3-氯-2-丙烯基羟胺肟化，得到目标化合物烯草酮。

Ingredients: Electrodialyzed Deep Sea Water, Disodium Laureth sulfosuccinate, Coco-Betaine, Mink Oil, Emu Oil, Jojoba Oil, Calendula Officinalis Flower Oil, Lavandula Angustifolia Fiower Oil, Rosmarinus Officinalis Oil, Rose Hip Oil, Borage Seed Oil, Daucus Carota Sativa Seed Oil, Eucalyptus Globulus Leaf Oil, Pelargonium Graveolens Oil, Lecithin, Tocopherol, Hydrolyzed Collagen, Hydrolyzed Elastin, Ubiquinone Ferment, Squalene, Sodium Hyaluronate, Retinol, Glycine Soya Phytoplacenta Extract, Ceramide, Panthenol, Allantoin, Melaleuca Alternifolia Extract, Rosa Damascena Flower Extract, Propolis Extract, Morus alba L.

主要成分：含海洋深层水， Disodium Laureth sulfosuccinate，可可甜菜碱，水貂油， Emu Oil， Borage Seed Oil，金盏菊花油，薰衣草油，迷迭香精油，玫瑰果油，胡萝卜素油，蓝桉叶油，天竹葵香薰精油，卵磷脂，维生素E，水解胶原蛋白，弹性蛋白水解，辅酶Q10，角鲨烯，透明质酸钠，视黄醇，甘氨酸大豆提取物，神经酰胺，D-L泛醇，尿囊素，互叶白千层提取物，突厥蔷薇，蜂胶，薄荷，芝麻，何首乌，银杏叶，枸杞，荨麻腿子属，洋甘菊，葛根等提取物

Taking the method of the indoor bioassay to study the herbicide antidote dichloro-N-acetyl-2-methyl-1-oxa-4-aza-Lo\nonane to reduce herbicide acetochlor on the stubble after the rice crop residues injury.

采用室内生物活性测定的方法，研究了除草剂解毒剂N-二氯乙酰基－2-甲基－1-氧杂－4-氮杂－螺[4.4]壬烷减轻除草剂乙草胺对后茬作物水稻的残留药害。

All dates were analyzed by the principal component analysis through using the SIMCA-P 10.0 software. Result: The PCA demonstrated that the metabolome between treated group and control group had difference in rat urine sample after of 22 days administrated, for treated group 169 kinds of biomarkers were found including oxalacetic acid, malic acid, 2-ketoglutaric acid, NE, arachidonic acid, 5-HIAA and other compounds, the result was consistent with pharmacological effects of R.coptidis , such as antiinflammatory, inhibiting biosynthesis of CA biosynthesis, anti-central nerve and energy metabolism inhibition.

结果：给药22 d，黄连组与对照组大鼠尿样代谢组有较大差异，发现了169个生物标记物，其中可能的化合物为草酰乙酸、苹果酸、2-酮戊二酸、去甲肾上腺素、花生四烯酸、5-羟吲哚乙酸等物质，这与黄连抗炎、阻止儿茶酚胺的生物合成、抑制中枢神经、降低能量代谢的药理作用相一致。

The extracts from evening primrose flower could significantly enhance the cellular immune function in immunosuppressed mice. Effects of ethylacetate extract was better than those of water extract.

月见草花乙酸乙酯提取物和水提取物均可明显增强环磷酰胺免疫抑制小鼠的细胞免疫功能，其中乙酸乙酯提取物的作用优于水提取物。

Methods The immuno-suppressive mice models were induced by intraperitoneal injection of cyclophosphamide (50mg/kg). T cell Proliferation response to ConA, the level of TNF-α and IFN-γ were determined after administering evening primrose flower extracts in high, medium and low-dose.

小鼠腹腔注射环磷酰胺(Cyclophosphamide， Cy)50mg/kg建立免疫抑制模型，然后将月见草花两种提取物分别以高、中、低三个剂量（低剂量437.5mg/kg、中剂量875mg/kg和高剂量1750mg/kg）每天1次灌胃，观察对小鼠脾脏T淋巴细胞增殖能力、肿瘤坏死因子－α(Tumor Necrosis Factorα， TNF-α)和干扰素－γ(Interferonγ， IFN-γ)分泌水平的影响。

Agriculture maize as Indicator plant, by raising it in soil with acetochlor, to study the herbicide antidote N-dichloroacetyl-2-methyl-1-oxa-4-aza-spiro-4.4-nonane on protect maize residual damage from acetochlor.the result of experiment is: the growths of maize is lower than comparison value.

以垦玉6号玉米为指示材料，采用土培法研究了除草剂解毒剂N-二氯乙酰基-2-甲基-1-氧杂-4-氮杂-螺[4.4]壬烷减轻除草剂乙草胺对玉米产生的残留药害。实验结果表明：在施用不同浓度的乙草胺土壤中，玉米植株的各项生长指标均低于空白对照值。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。