茚

The first synthetic route uses 1,2,4-trimethoxybenzene and chloroacetonitrile in forming 2,4,5-trimethoxy-a-chlor-acetophenone under the anhydrous condition, then the intermediate condensates with papaverine forming the core pyrro[2,l-a]isoquinoline, followed by formation and lactonization to form the lactone ring. The second synthetic route uses prepared aldehyde with prepared ethyl nitroacetate by Knoevenagel condensation to obtain 2-Nitro-3-(2,4,5-tris-methoxy-phenyl)-acrylic acid ethyl ester and 2-Nitro-3-(2,4,5-tris-benzyloxy -phenyl)-acrylic acid ethyl ester etal intermediates. The lamellarin skeleton could arise from condensation of the papaverine and these intermediates by Michael reaction, the ester group is provided for subsequent lactonization. The third synthetic route uses coumarin or indan-l,3-dione derivatives and papaverine to form lamellarin under basic conditions.

第一条路线首先从1，2，4-三甲氧基苯出发与卤乙腈作用合成卤代芳酮中间体，然后与罂粟碱反应合成开链片螺素，最后经乙酰化、去保护、成内酯环得到片螺素；第二条路线由制备的芳醛和制备的硝基乙酸乙酯经缩合得到2-硝基-3-芳基丙烯酸乙酯，然后由该中间体与罂粟碱反应，在完成关环的同时也引入酯基，最后去保护、成内酯环得到片螺素；第三条路线是由香豆素或茚二酮出发，经溴代后的中间体与罂粟碱反应，得到片螺素的基本框架。

For the first time, enantiomers of C2-symmetric 1,1 -spirobiindane-7,7'-diol were resolved with crude menthyl chloroformate by phase-transfer catalysis in the presence of tetrabutylammonium bromide. The reaction was carried out at 0℃-rt. The diastereomers of SPINOL bis-menthyl carbonate can be separated by simple crystallization using alcohol. The hydrolysis of the diastereomers was carried out via aqueous NaOH/EtOH solution.

首次通过相转移催化的方法对螺双二氢茚二酚进行了有效的拆分，用L--氯甲酸薄荷醇酯做拆分剂，以四丁基溴化铵为催化剂在0℃-室温下进行酯化反应生成非对映体衍生物，以乙醇作溶剂，通过重结晶的方法分离衍生物，在水-乙醇混合溶剂条件下，用强碱NaOH或KOH分别水解，制得相应的光学纯度大于99%ee的两个异构体SPINOL，其中总收率：--SPINOL，78.2%；--SPINOL，80.6%。

The process comprises polymerizing olefins in the presence of a supported indenoindolyl catalyst system and an organoboron or organoaluminum-treated solid.

该方法包括在茚并吲哚基载体催化剂体系和无机硼或无机铝处理的固体存在下聚合烯烃。

The intermediate which obtained from oximation of 7a-e reacted withmethyl N-(2-bromomethylphenyl)-N-methoxycarbamate to synthesize oxime ether methyl carbamate 3a-e.

以邻位卤代苯甲醛和3-丁烯-2-醇为原料通过钯催化&一锅法&反应合成了2-乙酰基茚7a-e，7a-e 肟化之后和N-(2-溴甲基苯基)-N-甲氧基氨基甲酸甲酯反应合成了肟醚类氨基甲酸甲酯3a-e，进一步胺解之后得到了肟醚类氨基甲酰甲胺3f-j。

A general method for preparing multi-cyclic indolizine compounds(1a—1c, 2a—2b and 3) in moderate yields(45%—71%) by a 1,3-dipolar cycloaddition reaction of pyridinium N-ylides, isoquinolinium N-ylides or quinolinium N-ylides to 1,4,4a ,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione, followed by an aromatization, in the presence of tetrakispyridine cobalt dichromate is described.

在 [ 4Co( HCr O4 ) 2 ]存在下，吡啶叶立德、喹啉叶立德或异喹啉叶立德分别和 1 ，4，4a，8a-四氢-1 ，4-桥亚甲基萘-5 ，8-二酮反应，一步法合成了中氮茚类多环化合物( 1 a～ 1 c，2 a～ 2 b，3 )。该方法原料易得，反应条件容易控制，为合成这类化合物提供了新方

This shows that spraying vegetables at the early instar larval stage with Abamectin+Indoxacarb 4.75 % WP(1: 1 000～1 500) and Emamectin benzoate 0.2 % EC(1: 1 000) can effectively control the diamondback moth.

研究认为，在低龄幼虫时使用4.75 %阿维·茚虫威WP 1 000～1 500倍或0.2 %高渗甲氨基阿维菌素苯甲酸盐EC 1 000倍防治小菜蛾，可以有效控制小菜蛾的发生危害。

Finally, we found that cycl[3.2.2]azines can be synthesized by carbonyl-couplinreactions using low valent titanium compounds from indolizinecarbaldehydderivatives.

最后，本文由中氮茚甲醛衍生物通过低价钛偶联反应，合成得到了cycl[3.2.2]azines，这是一条全新的合成cycl[3.2.2]azines的方法。

We developed a new method for the synthesis of cycl[3,2,2]azines.Using oxidant promoted 1,3-dipolar cycloaddition reaction, 3,5-dicarbonyl-indolizines were prepared. By treating with low-valenttitanium, cycl[3,2,2]azines were obtained in high yields.

我们通过l，3—偶极加成反应合成了多种3，5-二羰基中氮茚，然后在低价钛试剂作用下还原偶联，以较高收率得到各种取代Cycl[3，2，2]azine，开发了一种全新的Cycl[3，2，2]azine合成法。

ARDME company brought in the ELEC ION technology in 2008, ELEC ION anti-blackhead set sells in China by adopting the international and normal communication sale mode, set up the global uniform network sale system and the national uniform freephone number 400-8844-666, which provides much safer and more convenient international topranking products and service for Chinese customers.

08年，雅茚药妆将&ELEC ION&技术引进中国，ELEC ION去黑头净吸套装正式采用国际标准的通讯销售模式在中国销售，成立了全球统一网络销售系统和400-8844-666全国统一免费电话预订专席，专为中国消费者提供更加安全、快捷的国际一流产品与服务。

Among the special nine pollutants, however, eight of them, including Hexachlorobenzene, N-Nitrosodi-N-propylamine, 3,3-dichlorobenzidine, 2,4,6-trichlorophenol, 2,3,4,5,6-pentachlorophenol, indeno (1,2,3-cd) pyrene, 4,4'-DDT and Heptachlor were in need of concern while another chemical: dibenzanthracene be of special concern. The sources of these chemicals were discussed and some control strategies were suggested based on the risk assessment.

结果表明，有18种有机污染物超过了USEPA的标准浓度要求，其中9种物质具有一定的生态风险，其中六氯苯、N-亚硝基二正丙胺、3，3'-二氯联苯胺、2，4，6-三氯酚、五氯酚、茚并(1，2，3-cd)芘、4，4'-滴滴涕、七氯在内的8种化合物具有一定的风险，而多环芳烃二苯并蒽需要引起更高警惕；在此基础上探讨了这些化合物的来源及作用，并提出了相应的防治建议。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。