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This study also shows that the uptake of aglycone is much higher than that of glycoside.

本实验中黄酮普元的吸收均高于黄酮苷。

In previous work of helicid's structure modification show that 4 substituted groups of helicid are some ordinary acyclic and substituted aniline group, and it had no heptad heterocyclic substituted group.

在前期的豆腐果苷结构修饰工作中,豆腐果苷4位取代基多为一些简单的脂肪族、取代苯胺基等,尚无七元杂环作为取代基的此类化合物。

Constituting dicycle; 2. region selectively reducing six-membered ring ketocarbonyl radical; 3. introducing 7alpha-hydroxy group; 4. Aldol reaction to introduce side chain and obtain 8alpha-hydroxy group; 5. oxidizing the position 7 hydroxy group into ketone; 6. turning the configuration of the position 7 hydroxy group; 7. glycosidating the position 7 hydroxy group; and 8. eliminating protecting group to obtain the target compound.

该方法包括如下步骤:(1)双环的构建;(2)区域选择性还原六元环酮羰基;(3)7α-羟基的引入;(4)Aldol反应引入侧链,同时得到8α-羟基;(5)7位羟基氧化为酮;(6)7位羟基构型的翻转;(7)7位羟基的糖苷化;(8)脱除保护基得到目标化合物。

Diosgenin, a steroidal sapogenin, enhances antigen-specific IgG2a and interferon-γ expression in ovalbumin-sensitized BALB/c mice

题名: 类固醇皂苷;元diosgenin促进卵白蛋白免疫小鼠表现抗原专一性IgG2a抗体和伽马干扰素

The TLC of them were concordance.They presented the same color fluorescence in the corresponding position at the ultraviolet light(365nm). After the vanillic aldehyde sulphuric acid ethanol solution developed, violet color spots presented at the same place.

生远志正丁醇部位色谱和蜜远志正丁醇部位色谱基本一致:紫外灯(365 nm)下二者在相应位置呈相同颜色荧光,香草醛硫酸乙醇溶液显色后二者在相应位置的几个斑点均呈紫罗兰色,且远志皂苷元对照品斑点呈紫罗兰色,而在与其相应位置生远志供试品和蜜远志供试品均未检视到相应斑点。

MethodsAfter treated with DSS,the characteristics of isolated right atriums were investigated, including autorhythmicity,contraction scale,contraction velocity and relaxation speed.

目的研究3'大豆苷元磺酸钠对豚鼠离体右心房自律性及收缩特性的影响,并探讨其作用机制。

ResultsThe autorhythmicity of the isolated right atriums were inhibited after treated with DSS.

方法采用豚鼠离体右心房测定3'大豆苷元磺酸钠对其自律性、收缩幅度、收缩速度、舒张速度的影响。

ResultsThe autorhythmicity of the isolated right atriums were inhibited after treated with DSS. Moreover, their contraction scale,contraction velocity and relaxation speed were significantly reduced in a dose-dependent manner.

结果3'大豆苷元磺酸钠可降低豚鼠离体右心房的自律性,明显降低豚鼠离体右心房的收缩幅度、收缩速度、舒张速度,且具有明显的剂量依赖性。

OBJECTIVE To optimize the process of biotransformation of steroidal saponins in Dioscorea Zingiberensis C.H.

目的优化米曲霉直接转化盾叶薯蓣药材生成薯蓣皂苷元的工艺条件。

The flow rate was 1.0 ml/min and the detective wavelength was 250 nm.results:puerarin and daidzein had good linearities in the range of 0.21~1.40 μgand 0.03~0.20 μg,respectively.

结果:葛根素在0.21~1.40 μg、大豆苷元在0.03~0.20 μg范围内呈良好的线性关系;平均回收率分别为100.7%和99.6%,rsd分别为0.8%和1.6%。

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