苯酰胺

The induction of acylamide group can enhance the stereoselectivity of photochemistry and be used in other chemistry fields.

通过在二苯甲酮上引入酰胺羧酸类活性基团，不仅可以作为光化学前体用于提高光反应的立体选择性，而且还可直接应用于其他化学领域。

Two ligands L~Ⅵand L~Ⅶhave been designedand synthesized containing different terminal groups and using benzo-12-crown-4 as theskeleton, and their 18 rare earth nitrate and picrate complexes also have been synthesizedand characterized.

第二章：以五种不同种类水杨酰胺为功能末端基设计合成出以苯并-15-冠-5为骨架的配体L~Ⅰ～L~Ⅴ，并合成了其稀土硝酸盐和苦味酸盐的10个系列共51个稀土配合物。

To analysis bacterial-host infection, an in vitro experiment was first carried out to analyze the acid responses of Yersinia pseudotuberculosis, a gastro-intestinal bacterium, under acidic condition. Metabonomic variation of Y.

到21d时，天冬酰胺和组氨酸浓度降低，而缬氨酸、乳酸、丙氨酸、苹果酸、琥珀酸、GABA、胆碱、β-葡萄糖、果糖、尿囊素、苯丙氨酸、甲酸的含量增高。

D-p-hydroxyphenylglycine is one of the important side chain in the semi-synthetic-lactam antibiotic molecules widely clinically used in the world.

D-对羟基苯甘氨酸(D-p-hydroxyphenylglycine，D-HPG)是临床上广泛使用的半合成β-内酰胺类抗生素的重要结构部分。

The synthesis of the pentacyclic skeleton of Et-743 and the construction of the five chiral centers thereof.1. The core pentacyclic skeleton of phthalascidin was constructed with L-dopa as the starting material via thirteen steps. First, two basic synthons, the C-1 functionalized tetrahydroisoquinoline compounds 8 and N-protected Z-dopa derivative 9, were prepared from L-dopa. They were coupled via amide bond to form the dipeptide compounds 10, which were the first key intermediates. Then the primary hydroxyl groups were transformed into the corresponding amino aldehydes 11 via Swern oxidation. Followed by the intramolecular Pictet-Spengler cyclization, the pentacyclic compounds 12 were synthesized.

五环骨架的构建及五个正确手性中心的确立：1.1我们以L-多巴为起始原料，经过多步官能团保护和转化合成了基本结构单元8然后和苯丙氨酸衍生物9，通过缩合反应生成酰胺中间体10，经Swern氧化得到醛化合物11，然后再次利用分子内改良的Pictet-Spengler反应一步构建c，d两环，得到五环骨架化合物12，最后，实现了21-位羰基向氰基的转化，得到了C-1位官能化的化合物14，化合物14不但具有和Et-743一致的五环骨架，而且分子中五个手性中心立体构型也与其完全相同：其中，3，位和13，位的手性中心由原料L-多巴带入，而1，位，11，位和21，位手性中心则通过不对称诱导而确立。

The p-aminobenzene sulfpnamide group was connected to stilbene skeleton of stilbenes, and many twin drugs were prepared.

由拼合法将对氨基苯磺酰胺基团接到芪类化合物母体二苯乙烯骨架上，可得到多种孪生药物。

The results showed that mice in the photoallergy group pretreated with sulfanilamide and UV irradiation developed evident ear swelling at 24h after challenge and the histopathology was characteristic of DTH, while control mice showed no reaction, indicating that sulfanilamide is a kind of chemical with photoallergenicity.

结果显示，受试物对氨基苯磺酰胺仅在光变态反应组中于激发后24小时出现耳肿胀反应，耳组织学改变符合DTH的病理特征，在其余两个对照组中均不出现耳肿胀反应，证实为光变应性药物。

Methyl-4-aminobenzyl sulfonamide, a key intermediate for synthesis of the pharmaceutical substance Sumatriptan, was prepared throught four steps.

甲基 4 氨基苯甲基磺酰胺是一种重要的医药中间体，主要用于合成药物舒马普坦。

The preparation of a novel chiral sulfonamide alcohol derived from natural camphor and its application in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to benzaldehyde is described.

由天然樟脑合成了一个新手性磺酰胺醇，并对其在二乙基锌对苯甲醛的对映选择性加成中的催化性能进行了研究，获得了73%化学产率和

The invention belongs to the synthesis technical field of pharmaceutical intermediates, and more particularly relates to a preparation method of Cis-4-(2-bromine ethylene) benzene sulfonamide.

本发明属于药物中间体合成技术领域，具体涉及一种顺式-4-(2-溴乙烯基)苯磺酰胺的制备方法。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。