苯酰化物

The effects of above-mentionedconditions on alkylene reaction are studied to obtain the optimum reactive conditionsby orthogonal experiments having seven factors and three levels. GCLE is chosen as material to prepare 7-phenyl acetamideyl vinyl cephalkyl acidp-methoxy benyl eatsr in the experiment. The process is as follow: GCLE reacts withiodide in solvent, and produce 3-iodid, then reacts with PPh_3 to produce Witting agent,and reacts with HCHO to produce 7-phenyl acetamideyl vinyl cephalkyl acid p-methoxy benyl eatsr in alkaline conditions.

试验选用GCLE作为原料制备7-苯乙酰氨基-3-乙烯基头孢烷酸对甲氧苄酯，反应过程如下：GCLE与碘化物、PPh3在溶剂中反应生成3位膦盐，在碱性条件下生成Wittig试剂再与HCHO反应生成7-苯乙酰氨基-3-乙烯基头孢烷酸对甲氧苄酯。

Experimental process: jing and 3- methyl -2- methyl ethyl ketonesynthesizes by the benzene zong; Again the glacial acetic acidcatalysis produces 2, 3, 3 - trimethyl - 3H - yinduo; Again has thealkylate response production yinduo iodide after the methyl iodide;The iodide takes off molecular HI under NaOH to become freejier thealkali; Adds 5 - nitryls salicylic aldehydes in the ethyl alcohol forthe solvent under if to respond finally produces 6 '- the nitryl yinduolin spiral benzene and pinan; Through the infrared spectrum andthe ultimate analysis irrevocably proved its structure, and studiedthe annulus with to open the annulus the light to send changes colorthe performance, explained in different solvent medium ultravioletabsorption spectrometry solvent effect, and the comparisondiscoloration the response speed number difference, finally mixed itadds to the methyl methacrylate, the peroxidation benzoin formyl in the plexiglass, tested 6 '- the nitryl yinduolin spiralbenzene and pinan in the glass fatigue resistance, thethermostability.

实验过程：由苯肼和3-甲基-2-丁酮合成腙；再冰醋酸催化生成2 ，3 ，3—三甲基—3H—吲哚；再经过碘甲烷发生烷基化反应生成吲哚碘化物；碘化物在NaOH下脱去一分子HI成为费歇尔碱；在乙醇为溶剂下加5－硝基水杨醛与其反应最后生成6'—硝基吲哚啉螺苯并吡喃；通过红外光谱和元素分析确证其结构，并研究了环体与开环体的光致变色性能，解释了在不同溶剂介质中紫外吸收光谱的溶剂效应，并比较褪色反应速率数的差异，最后将其掺加到甲基丙烯酸甲酯，过氧化二苯甲酰有机玻璃中，测试6'—硝基吲哚啉螺苯并吡喃在玻璃中的抗疲劳性、热稳定性。

PEG400, which is poisonless, low cost with good capability of carrying sodium ion, was used as catalyst, and sodium cyanide owing to its less toxicity, stability, less amount in the reaction, was used as cyanating reagent in the reactions.

在有机卤代化合物或酯与PEG400、NaCN的用量比分别为1∶0.03和1∶1.3的条件下，获得了高收率（84％-96％）和高纯度（≥98％）的腈化物。通过几种不同溶剂下反应的对比，选择了以苯为溶剂，在酰氯与PEG400、 NaCN的用量比分别为1∶0.05和1∶1.2及反应温度为室温的条件下，合成了酰基腈化物。

In our work, as a preliminary experiment, the N-phenacylisoquinolinium bromide was reacted with methlhydrazine in refluxed acetic acid. Unexpectedly, 2-methyl-1,2,3-triazole was obtained. The further study of this reaction led to a more simple starting material,α-bromoacetophenone to react with methylhydrazine, obtaining the same product.

我们在研究N-苯乙酰异喹啉溴化物与甲肼在冰醋酸中的反应时，意外地得到了2-甲基-4-苯基-1，2，3-三氮唑，经过进一步的研究发现α-溴代苯乙酮与甲肼也能得到同样的产物。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。