苯甲酰化

Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

From 3-chloropropene bycondensation with sodium ethylate in ethanol to form 3-ethoxypropene followed by anti-Markovnikov addition with HBr inthe presence of benzoyl peroxide.

3-氯丙烯与乙醇钠在乙醇中回流制得3-乙氧基丙烯，继而在过氧苯甲酰存在下，与溴化氢经反马氏加成制得1-溴-3-乙氧基丙烷，总收率89。

Three formyl group functional cross-linking polystyrene resins of p -formylphenoxymethyl, p -formyl-2-methoxphenoxymethyl,and p -formyl-3-methoxphenoxymethyl were facilely and rapidly synthesized from Merrifield resin under phase transfer catalytic condition coupling with microwave irradiation in a domestic microwave oven.

以Merrifield树脂为原料，家用微波炉为反应装置，在微波照射的相转移催化条件下，简便快速地合成了3种甲酰基功能化的交联聚苯乙烯树脂——对甲酰基苯氧基甲基树脂、对甲酰基-2-甲氧基苯氧基甲基树脂和对甲酰基-3-甲氧基苯氧基甲基树脂。

Three formyl group functional cross-linking polystyrene resins of methoxphenoxymethyl, and p-formyl-3-methoxphenoxymethyl were facilely and p-formylphenoxymethyl, p-formyl-2-rapidly synthesized from Merrifield resin under phase transfer catalytic condition coupling with microwave irradiation in a domestic microwave oven.

以Merrifield树脂为原料，家用微波炉为反应装置，在微波照射的相转移催化条件下，简便快速地合成了3种甲酰基功能化的交联聚苯乙烯树脂--对甲酰基苯氧基甲基树脂、对甲酰基-2-甲氧基苯氧基甲基树脂和对甲酰基-3-甲氧基苯氧基甲基树脂。

IR studies of Co metal ion complexes with salicylaldehyde benzoyl hydrazone in solid state brings out the deprotonation of phenol in the formation of Co in pH 5—6 solution.On the contrary,the phenol is protonated in the formation of Co 2 in pH 8—10 solution,which is the same as the result of Zn 2 formation.

水杨醛苯甲酰腙钴络合物在固态的红外光谱分析表明，p H约 5— 6时，生成的络合物Co中的酚羟基脱质子，当 p H控制在 8— 10时，生成的络合物 Co 2 酚羟基质子化，即酚羟基未脱除质子，与络合物 Zn 2 的 IR结果相同。

Last, we studied the allylation of benzoylhydrazones with allyltrichlorosilane.

在研究过程中，发现了一个C=N双键烯丙基化的新方法，和苯甲酰肼的新的合成方法。

Amination reaction was carried out at temperature of 90℃ to 150℃ for 2h to 10h and then ashless dispersant of polyisobutylene succinimide would be obtained after dehydration with the operations of vacuum distillation and filtration.

结果发现，实验在N_2保护下进行，BPO／PIB质量比为0.035，MA／PIB摩尔比为1.3，反应温度为150℃，反应时间为12h，搅拌速率为250rpm，引发剂过氧化苯甲酰以丁酮为溶剂分六次，时间间隔为30分钟，均量地加入反应器时，烃化反应物聚异丁烯的转化率最高。

The liquid-phase hydrogenation is performed by controlling the concentration of a benzamide compound to a specific level or lower.

通过控制苯甲酰胺化合物的浓度至特定水平或更低，进行液相氢化作用。

The copolycondesation type polyamic acid was synthesized by using pyromellitic dianhydride and 3,3',4,4'-benzophenonetetracarboxylic dianhydride as the dianhydride monomers, 4,4'-diamino diphenylmethane and 4,4'-oxydianiline as the diamine monomers under microwave irradiation in dimethylformamide.

在N，N'-二甲基甲酰胺溶剂中，以均苯四甲酸酐和3，3'，4，4'-二苯酮羧酸二酐为二酐单体，4，4'-二氨基二苯醚和4，4'-二氨基二苯甲烷为二胺单体，采用微波辐射低温溶液共缩聚，合成了聚酰胺酸预聚体，然后亚胺化脱水、环化，生成共缩聚聚酰亚胺。

METHOD Dofetilide was synthesized by steps of reaction (substitution ,reduction, methylsulfonylation and methylammoniation, etc) from p-nitrophenol and p-amino phenethyl alcohol.

以对硝基苯酚为起始原料，经取代、还原、甲磺酰化等反应制得 4甲磺酰苯胺(5 )；以对氨基苯乙醇为起始原料，经甲磺酰化、甲氨化等反应制得 4 甲磺酰苯胺(8)，再与5经取代反应制得多非利特。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。