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苯甲基

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Water,Hydrogenated Polyisobutene,Cyclohexasiloxane,Glycerin,Alcohol Denat,Cetearyl Alcohol,PEG-20,Petrolatum,C13-14 Isoparaffin,Zea Mays Oil,Tocopheryl Acetate,Hydroxypropyl Tetrahydropyrantriol,Hydrolyzed Soy Protein,CI 14700/Red 4,Phenoxyethanol,Adenosine,PEG-100 Stearate,Ethylparaben,Triethanolamine,Polyacrylamide,Malus Domestica Stem Cell Culture,CI 19140/Yellow 5,Dimethyl Isosorbide,Dimethicone,Dimethiconol,Limonene,Xanthan Gum,Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate,Linalool,2-Oleamido-1,3-Octadecanediol,Capryloyl Salicylic Acid,Acrylates/C10-30 Alkyl Acrylate Crosspolymer,Passiflora Edulis Seed Oil,Disodium EDTA,Castanea Sativa Seed Extract,Butyrospermum Parkii· Cetyl Alcohol,Butylene Glycol,Octyldodecanol,Cetearyl Glucoside,Methylparaben,Citronellol,Prunus Armeniaca Kernel Oil,Laureth-7,Coumarin,Oryza Sativa Bran Oil,Glyceryl Stearate,Fragrance

水,甘油,氢化聚异丁烯,液体石蜡/矿油,丁二醇,环己硅氧烷,鲸蜡醇,甘油硬脂酸酯,棕榈油,玉米胚芽油,PEG-100硬脂酸酯,白蜂蜡/蜂蜡,肉豆蔻醇肉豆蔻酸酯,石蜡,香精,腺苷,苧烯,山梨醇,CI 14700,CI 19140,稻糠油,杏仁油,EDTA二钠,羟丙基四氢吡喃三醇,苯氧乙醇,聚乙二醇-14M,异十六烷,氢氧化钠,辛基十二醇,季戊四醇四(双-t-丁基羟基氢化肉桂酸)酯,山梨坦三硬脂酸酯,水解大豆蛋白,卡波姆,鸡蛋果籽油,苹果果实提取物,欧洲栗籽提取物,异山梨醇酐二甲醚,聚山梨醇酯-80,辛酰水杨酸,2-油酰胺基-1,3-十八烷二醇,氯苯甘醚,麦芽糖醇,香豆素,黄原胶,微晶蜡,丙烯酰胺/丙烯酰基二甲基牛磺酸钠共聚物,丙二醇,芳樟醇,香茅醇,玉米油,羟苯丙酯,羟苯甲酯

The initial SAR studies indicated:(1) the presence of a linker of methene at the N-1 may be beneficial to anti-HIV activity, while longer chain could enhance toxicity;(2) substituted phenyl at the C-2 could reduce toxicity;(3) 6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4) the presence of a halogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示:(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好,侧链延长,毒性增大;(2)苯并咪唑2位侧链无间隔基毒性相对较低;(3)苯并咪唑6位取代活性高于5位取代;(4)苯并咪唑1位芳环用卤素取代,毒性明显降低。

The initial SAR studies indica ted:(1)the presence of alinker of methene at the N-1may be beneficial to anti-HIV activity,while longer chain could enhance toxicity;(2)substituted phenyl at the C-2could reduce toxicity;(3)6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4)the presence of ahalogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示:(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好,侧链延长,毒性增大;(2)苯并咪唑2位侧链无间隔基毒性相对较低;(3)苯并咪唑6位取代活性高于5位取代;(4)苯并咪唑1位芳环用卤素取代,毒性明显降低。

During the manufacturing of the critical intermediate cephalosporin nucleus --7-amino-3-chloro-cephalosporanic acid diphenylmethyl ester hydrochloride salt, first the feasibility of the one-pot synthetic route of open loop, closed loop and ozonization when chlorine is passed over is qualified by experiments. Then the critical factors that will influence this reaction are studied as follows: the mol ratio of triphenyl phosphite and Diphenylmethyl 3-hydroxy-7-phenylacetaminoceph-3-em-4-carboxylate-l-oxide is four to one; the quantity of the stablizer should be at least more than two to one. The temperature of the system must be 25℃ when chlorine is passed over so that the hydrochloride can be precipitated to obtain cephalosporin nucleus of cefaclor--7-amino-3-chloro-cephalosporanic acid diphenylmethyl ester hydrochloride salt.

在制备关键中间体头孢母核7-氨基-3-氯头孢烷酸二苯甲酯盐酸盐时,先通过实验验证把开环、闭环、臭氧化三步在通入氯气时并为一锅煮的合成路线的可行性之外,又研究了影响该反应的几个重要因素:亚磷酸三苯酯与3-羟基-7-头孢烷-5-亚砜-2-甲酸二苯甲酯的摩尔比为4:1;稳定剂2-甲基-2-丁烯的用量至少大于2:1,通入氯化氢气体时体系温度在25℃时盐酸盐则能够顺利析出,获得头孢克洛的头孢母核—7-氨基-3-氯头孢烷酸二苯甲酯盐酸盐。

The response to single compound: To both females and males, the compounds that elicit larger responses of adults are benzaldehyde, benzene acetaldehyde, hexanol,β-phenyl ethyl alcohol, benzyl alcohol, cyclohexanol and eugenol. Phytol, 2-methyl-cyclohexanone and β-caryophyllene reveal to have weaker activity.

对单一化合物的反应:两种昆虫,不论是雌蛾还是雄蛾,能引起较强EAG反应的化合物均为苯甲醛、苯乙醛、正己醇、β-苯乙醇、苯甲醇、环己醇和丁香酚,植醇、2-甲基环己烷和β-石竹烯仅能引起微弱的EAG反应。

Besides, the derivatives were synthesized successfully by the similar acid binding agent system, such as tris(4-nitrophenyl) thiophosphate, tris(4-toluene)thiophosphate. The derivative of maleic anhydride was synthesized by the simple method, and its yield was above 90%.

采用类似的缚酸剂体系成功地合成了硫代磷酸三(4-硝基苯)酯、硫代磷酸三(4-甲基苯)酯,并用简单的方法合成了硫代磷酸三(4-氨基苯)酯的马来酸酐衍生物——硫代磷酸三(4-马来酸氨基苯)酯,产率达90%以上。

Poly with sulfonic acid groups were readily synthesized with biphenol and 1,3-bis(4-fluorobenzoyl)benzene in the presence of excess potassium carbonate followed by sulfonation with chlorosulfonic acid.

以二氯二苯甲烷和2,6-二甲基苯酚为原料合成了含有阻碍基团的双酚单体,用此双酚单体和1,3-二(4-氟苯甲酰基苯)在无水碳酸钾存在的条件下反应制得聚芳醚酮,然后用氯磺酸磺化,控制反应条件,使磺酸基团恰好进入苯环对位,制得新型结构的磺化聚芳醚酮。

The copolycondesation type polyamic acid was synthesized by using pyromellitic dianhydride and 3,3',4,4'-benzophenonetetracarboxylic dianhydride as the dianhydride monomers, 4,4'-diamino diphenylmethane and 4,4'-oxydianiline as the diamine monomers under microwave irradiation in dimethylformamide.

在N,N'-二甲基甲酰胺溶剂中,以均苯四甲酸酐和3,3',4,4'-二苯酮羧酸二酐为二酐单体,4,4'-二氨基二苯醚和4,4'-二氨基二苯甲烷为二胺单体,采用微波辐射低温溶液共缩聚,合成了聚酰胺酸预聚体,然后亚胺化脱水、环化,生成共缩聚聚酰亚胺。

The mechanism of outside cell reaction of electrosynthesis of p-methoxybenzaldehyde and p-bromobenzaldehye is studied by Fourier-transform infrared absorption spectra.

利用红外光谱研究了槽外合成对甲氧基苯甲醛和对溴苯甲醛的反应机理,结果证明:在Ce4+与对取代甲苯的氧化反应中,苯环上甲基被Ce4+氧化的难易受苯环上对位取代基的影响。

Among the six polyetherimdes, ODPA-IPDA with the largest free-volume and larger intrasegmental mobility has the highest permeability and the lowest permselectivity, ODPA-DABP with the smallest free- volume and the smallest intrasegmental mobility has the lowest permeability and the lowest permselectivity, ODPA-DMMDA with the larger free-volume and smaller intrasegmental mobility has higher permeability and higher permselectivity.

二苯醚四酸二酐(ODPA-4.4'-二J氨基二苯异丙烷具有很大的自由体积和较小的链段活动性、很大的透气性和较小的透气选择性,ODPA—4,4'-二氨基二苯酮具有很小的自由体积和较小的链段活动性、很小的透气性和较大的透气选择性,ODPA—3,3'-二甲基二苯甲烷二胶具有较大的自由体积和较小的链段活动性、很大的透气性和很大的透气选择性。

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Detailed Intrinsic Reaction Coordination calculations were carried out to guarantee the optimized transition-state structures being connected to the related tautomers.

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