苯核

In the nucleus accubens and amygdaloid of rats, the NR2B expression participated in the mechanism of antagonistic effect of rhychophylline on amphetamine dependence.

伏核和杏仁核NR2B蛋白表达参与了钩藤碱抗苯丙胺依赖作用的分子机制。

Objective: To study the effect of rhynchophylline on NMDA receptor 2B subunit (NR2B) in nucleus accubens and amygdaloid of amphetamine-induced condictioned place preference rats.

目的：研究钩藤碱对苯丙胺依赖大鼠伏核和杏仁核中NR2B蛋白表达的影响。

On the one hand, one benzen ring of stilbene was substituted by one pyridine ring for the purpose of evaluating the bioactivities of azastilbenes. On the other hand, some stilbene derivatives with different substituents in different sites were designed for the study of SAR.

一，以吡啶环替代母核的一个苯环，考察分子中引入氮原子对活性的影响；二，改变母核上的取代基类型及取代位点，考察取代基在构效关系中的影响规律。

In the second approach, terephthalaldehyde was also used as starting material, which reacted with cyanoacetic acid in pyridine to afford tetra-nitrile compound.

在第二种合成路线中，我们仍然以对苯二甲醛为起始原料，对苯二甲醛与氰基乙酸反应得到四氰基化合物8，再经过官能团转换、还原、亲核取代、分子内Friedel-Crafts反应得到中间体H〓TTPR。

Afterwards, N-(6-chloro-3-pyridinemethyl) phthalimide is prepared by using potassium phthalimide, as nucleophilic reagent, condensation reacting with 2-chloro-5-methylpyridine at a temperature of 70℃.

然后在70℃条件下，以邻苯二甲酸亚胺钾作为亲核试剂，与2-氯－5-氯甲基吡啶发生缩合反应，制备了N-（6-氯－3-吡啶甲基）邻苯二甲酰亚胺。

Amino-monomethoxypoly(ethy1ene glycol)(mPEG-NH2) was synthesized based on the principle of Gabriel synthesis.Monomethoxypoly(ethy1ene glycol) tosylate was prepared at first,and then reaction with potassium salt of phthalimide as nucleophile to produce the monomethoxypoly(ethy1ene glycol)phthalimide derivative.

摘 要：首先合成了单甲氧基聚乙二醇对甲苯磺酸酯，然后根据盖布瑞尔合成法原理，以邻苯二甲酰亚胺钾盐为亲核试剂与mPEG-OTs反应，生成单甲氧基聚乙二醇的邻苯二甲酰亚胺衍生物，mPEG-PI与水合肼反应肼解生成伯胺，合成了一端为氨基的单甲氧基聚乙二醇(mPEG-NH2)。

Gabriel reaction was adopted to synthesis 2-(0ctahydro-1-azocinyl)ethylamine, N-(β-Heptamethyleniminoethy1)phthalimide was prepared by treating Heptamethylenimine with N -(β-bromoethy1) phthalimide. N -(β-bromoethy1) phthalimide was easily prepared from phthalic anhydride in two steps.

我们采用Gabriel伯胺合成法制备2-环庚亚胺基乙胺，从邻苯二甲酸酐经过两步反应很容易地得到N-邻苯二甲酰亚胺，然后与环庚亚胺发生亲核取代反应，产物再水解制得伯胺2-环庚亚胺基乙胺。

Methods: Eleven B-CLL patients were studied. Leukemic lymphocytes with (n=8) or without (n=3) P2z receptors were exposed in vitro to ATP, benzoylbenzoic-ATP, 2-methylthio-ATP(2MeSATP), adenosine-5′-［γ-thio］ triphosphate, and other nucleosides for 8h. Apoptosis was detected by electron microscopy, agarose gel electrophoresis, and quantitative TdT assay. Results:Apoptosis was detected only in leukemic lymphocytes with P2z receptors. By using the quantitative assay, ATP-inducing DNA strand breaks were found to occur specifically for BzATP, ATP and 2MeSATP, but not for ATP-γS and other nucleosides.

将表达P2z受体［P2z］与不含P2z受体［P2z］的两组CLL细胞分别同1.0mmol/L三磷酸腺苷体外培养8小时，以电镜、DNA凝胶电泳和定量DNA 3′端TdT法检测细胞凋亡；并对ATP、苯甲酰苯甲酸ATP、2-甲基硫ATP(2MeSATP)、γ-硫代ATP及其它核苷的诱导效应和氧化型ATP、1-［N，O-二(5-异喹啉碘酰基)N-甲基-L-酪氨酰］-4-苯哌嗪KN-62）的抑制效应做定量研究。

We have synthesized two new conjugated dendrimers bearing triphenylamine moiety as dendrons and 1, 3, 5 triphenylbenzene as a core through a simple Wittig-Horner reaction.

通过Wittig-Horner和Heck反应设计并合成了以含醛基的树枝状三苯胺为树突，以三苯苯为核的dendrimers (TPB-TPA3和TPB-TPA9)。

With the progress of nuclear medicine and space physiology, People become more and more interesting in the radiation injury and it s protection study.

中文摘要：目的核医学和航天科学的进步使人们对放射性损伤及其防治越来越重视，我们在前期已进行了苯二氮革类药物及苯二氮受体在放射性脑损伤防护中的机理研究。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。