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苯并咪唑

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In this study, the classification of Chinese Babesia spp. infective to cattle were carried out by the classical methods and molecular biotechnology, and investigated the vector ticks of an unidentified Babesia sp. isolated from Xinjiang province by the experimental transmission, and observed the developmental forms of Babesia sp. in the engorged Hyalomma anatolicum anatolicum females;We developed the indirect hemoagglutination test for Babesia bigemina, and evaluated its effect in the sero-survey;We made slow-released injection of imidocarb, and estimated its efficacy on the treatment and prevention of Babesia bigemina infection by the laboratory work and the field tests. The major results were presented as following:1. Discovery of a bovine Babesia sp.

本研究以牛的巴贝斯虫为研究对象,采用传统技术与分子生物学技术相结合的方法对在我国已分离的牛巴贝斯虫病主要病原进行了分类学研究,在实验室内运用蜱传播试验对分离于我国新疆的牛的巴贝斯虫未定种的媒介蜱及其传播方式进行了详细的研究,采用组织抹片方法对牛的巴贝斯虫未定种在小亚璃眼蜱饱血雌虫体内的发育过程进行了观察;建立了间接血球凝集试验诊断方法,并对其在血清学调查中的应用效果进行了考察;研制了咪唑苯脲缓释注射剂,并通过实验室工作和田间试验对防治效果进行了评价。

Benzoin condensation using imidazolium based ionic liquids as solvent for the first time has been successfully achieved. The reaction conditions have been studied in detail. When under 65 and with 0.5 equiv. NaOH in ionic liquid l-butyl-3-methyl-imidazolium tetraborate, benzoin was obtained in excellent yield of 91%. Recycling of ionic liquid has been available.

首次探索并成功实现了在咪唑鎓盐离子液体中进行苯偶姻缩合反应,详细探讨了反应条件,当反应在65℃下和0.5当量NaOH存在下以及在离子液体4-丁基-1-甲基咪唑鎓四氟硼酸盐中进行时,苯偶姻产率可达91%;并对离子液体进行了有效回收再利用。

The efficacy of triclabendazole made in China was tested againstFasciola hepatica in naturally infected goats and compared with that of niclofolan.

以国产三氯苯咪唑对自然感染肝片形吸虫的山羊进行了驱虫试验,并以硝氯酚为药物对照。

In addition, the stability of ternary Cu 〓complexes polypyridyl=1, 10-phenanthroline (Phen , pyrido [3, 2-f] [1, 7] phenanthroline , 1, 4, 8, 9-tetraazatriphenylene , dipyrido [3, 2-a: 2'3'-c] phenazine , imidazo phenanthroline and 2-phenylimidazo phenanthroline , NTP=ATP and UTP was studied by potentiometric pH titration in water at temperature 15℃, 25℃ and 35℃, and in 30% and 50% aqueous dioxane solution at 25℃.

另外,用pH电位滴定法研究了多吡啶芳香配体polypyridyl配合物Cu〓(PL=1,10-邻菲咯啉、吡啶并[3,2-f][1,7]邻菲咯啉、1,4,8,9-四氮三联苯、二吡啶并[3,2-a∶2'3'-c]吩嗪和2-苯基咪唑并邻菲咯啉或咪唑并邻菲咯啉)在不同温度(15℃、25℃和35℃)水溶液及30%和50%二氧六环-水混和溶剂(25℃)中的稳定性。

Curing reactions of BPF/R EP system containing dicyandiamide were studied with differential scanning calorimetry,and the curing systems and curing condition were studied systematically with 2-ethyl-4-methyl imidazole(2E4MZ) accelerating dicyandiamide,which affected the property of BPF/resorcin copolymeriza.

通过差示扫描量热法研究了2-乙基-4-甲基咪唑对双氰胺-双酚F/间苯二酚共聚型环氧树脂体系固化反应的促进作用,并系统地探讨了固化体系及固化条件对固化物性能的影响。

The thesis was mainly focused on the synthesis and synthetic methods ofimidazole, chromene, triazine, isoquinolin derivatives and divided into five sectionsbased on the contents.

中文摘要:论文对咪唑、苯并吡喃、三嗪和异喹啉类化合物的合成及其方法学进行了较系统的研究,依据其内容分为五个部分。

One class is CAAX-mimetic compounds with an imidazolyl residue on one end and a carboxylic group on the other connected by benzodiazepine scaffold at different positions.

连有咪唑基的苯并二氮杂草化合物,以苯并二氮杂草-2-酮为分子骨架,7位连接含有咪唑基的侧链,1位或3位连接含羧基或酯基的侧链。此类化合物模拟了CAAX配体。

As CAAX-mimetics, 1, 3-dihydro-5-phenyl-2-H-1, 4-benzodiazepin-2-one was modified by linking carboxyl groups with various carbon through N-1 and C-3, 3-(imidazol-4-yl) propion amido group with different substituents was connected at C-7; In the synthesis of bisubstrate analogues, thiocarbamido compounds was alkylated by alkyl iodide and then hydrolyzed to give alkylthiol benzoate compounds.

1,4-苯并二氮杂草-2-酮类化合物的合成过程中分别对其1、3、4和7位进行了基团变化,在1和3位连接不同长度含羧基或酯基的侧链,在7位连接不同取代的咪唑丙酰氨基。在苯甲酸硫醇酯化合物合成过程中,建立了一种硫原子连有不同长度碳链的苯甲酸硫醇酯的合成方法。

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