苯并呋喃

Further investigation in this area leads to discovery of a new synthesis of benzofuran.

本部分工作不仅发展出了一条合成苯并二氢呋喃的新方法，而且展示了苄基化反应在合成中的应用潜力。

In the precence of the base catalyst KF/Al2O3, the one - pot reaction of 2 -hydroxybenzaldehyde or 2 - hydroxynaphthaldehyde with ethyl α- bromoacetate,α-bromoacetophenone , 1,4 - dichloromethylbenzene , 4,4'- dichloromethylbiphenyl and 1,5 -dichloromethylnaphthalene gave the benzofuran compounds in 38-89% yield.

本文报道用 KF/Al_2O_3作为碱催化剂，由水杨醛或2-羟基-1-萘醛分别和α-溴代乙酸酯、α-溴代苯乙酮、苄基氯、4，4'-二氯甲基联苯和1，5-二氯甲基萘等进行一锅化缩合反应，以38～89％的产率合成了14种芳并呋喃化合物。

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

Based on the analysis of bibliographer and evaluation of the principles of different processes, the novel process for synthesis of the new type of polyheterocyclic disperse dyestuff , unsymmetrical benzodifuranones and its intermediates was studied in the dissertation.

论文在查阅国内外有关文献基础上，对不对称苯并二呋喃酮系新型稠杂环分散染料的分子设计、应用特性及研究进展作了概述，对此类稠杂环分散染料及其中间体的合成路线和方法作了综合评述。

They are 4-(2- hydroxy-3-butynlenoxy) benzoic acid (1, WA), 5-chloro-7, 8-dihydroxy-7-methyl- 6-oxo-3- [ -3, 4-dihydroxy-3, 5-dimethyl-l-heptylene] -1H-8, 8a-dihydrobenzo [2, 3-c] pyran (2, WB),-2-(2-methyl-2-dibutene diamido)-2-butenoic acid (3, B5262), 3, 4-dihydro-9, 10-dihydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3- c] pyran-1-one (4, A73 semi-Vioxanthin), 8, 8'-bis (6, 9-dioxo-3,4-dihydro-10- hydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3-c] pyran-1-one)(5, A122 Xanthomegnin), 2, 5-dioxo-3a-hydroxymethyl-3, 3a, 6, 6a-tetrahydro-furo [2, 3-b] furan (6, 1003-2), 7-acety1-5-chloro-6, 8-dioxo-7-methyl-3- [ -3, 5-dimethyl-1, 3- diheptylene] -4aH-benzo [2, 3-c] pyran (7, M2-2 sclerotiorin), respectively.

它们分别被命名为4-（2-羟基-3-丁炔氧基）苯甲酸（1，WA）、5-氯-7，8-二羟基-7-甲基-6-氧代-3-[-3，4-二羟基-3，5-二甲基-1-庚烯基]-1H-8，8a-二氢苯并[2，3-c]吡喃（2，WB）、-2-（2-甲基-2-丁烯二酰亚胺基）-2-丁烯酸（3，B5262）、3，4-氢-9，10-二羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮（semi-Vioxanthin，4，A73）、8，8'-双（6，9-二氧代-3，4-二氢-10-羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮）（Xanthomegnin，5，A122）、2，5-二氧代-3a-羟甲基-3，3a，6，6a-四氢-呋喃并［2，3-b］呋喃（6，1003-2），7-乙酰基-5-氯-6，8-二氧代-7-甲基-3-［-3，5-二甲基-1，3-庚二烯基］-4aH-苯并2，3-c］吡喃（Sclerotiorin，7，M2-2）。

According to the differences of the materials, there are many methods of synthesis for benzofuranol , such as the pyrocatechol method, the cyclohexanone method, the o-chlorophenol method, the nitrophenol method, the methoxy phenol method, and so on.

根据原料的不同，呋喃酚合成方法可分为邻苯二酚法、邻氯苯酚法、环己酮法、硝基苯酚法、愈创木酚法、邻异丙基酚法、羟基苯异酮法等，文章对前几种较常见的合成方法的原理及工艺进展进行了详细的综述，并展望了呋喃酚合成方法的发展趋势。

The thesis concerning about the total synthesis of some natural occurringlignans and neolignans consists of following five parts:I. Progress in the synthesis of some natural occurring neolignans A view of the synthesis of some natural occurring neolignans, especiallybenzofuraniod and bicyclo[3, 2, 1]octanoid neolignans was given. The syntheticmethods for this two kind of neolignans have been classified and discussed.Ⅱ.

本论文研究了一些木脂素和新木脂素类天然产物的全合成，共包括五部分内容：一、一些新木脂素类天然产物的合成进展对一些新木脂素类天然产物尤其是苯骈呋喃类和双环[3，2，1]辛烷类新木脂素的合成工作进行了较为全面的介绍，并对此类化合物的合成方法进行了分类和讨论。

Good thermal stability and self-extinguishing behavior was observed with the cured polybenzoxazine resins. Second, furan-containing benzoxazine monomers, P-FBz, BPA-FBz, and 4FP-FBz were prepared using furfurylamine as a raw material. Formation of furfurylamine Mannich bridge networks in the polymerizations of P-FBz and BPA-FBz increased the cross-linking densities and thermal stability of the resulting polybenzoxazines. P-FBz and BPA-FBz- based polymers also exhibited high glass transition temperatures above 300℃, high char yields, and low flammability with a limited oxygen index value of 31. The dielectric (Dk3.21–3.39) and mechanical properties (high storage modulus of 3.0–3.9 GPa and low coefficient of thermal expansion of 37.7– 45.4 ppm) of the P-FBz and BPA-FBz-based polymers were superior or comparable to other polybenzoxazines. 4FP-FBz used for polybenzo- xazine modification by means of formation of benzoxazine hybridation with P-FBz.

第二部份以2-呋喃甲胺为起始物，制备了P-FBz、4FP-FBz与BPA-FBz 三个含呋喃官能基之氧代氮代苯并环己烷的单体；BPA-FBz与P-FBz於开环聚合中形成之Mannich bridge网状结构有效地提升聚氧代氮代苯并环己烷聚合物之交联密度与热安定性；Poly与Poly具有大於300℃之玻璃转移温度、高的焦炭生成率与具有31之极限氧指数(Limited oxygen index， LOI)的难燃性特质，Poly与Poly之介电常数(Dk=3.21~3.39)与机械性质[3.0~3.9 GPa的储存模数与37.7~45.4ppm之低热膨胀系数( Low coefficient of thermal expansion， Low CTE)]均较其他聚氧代氮代苯并环己烷为优；4FP-FBz具有低之介电常数(Dk=2.7)，以其作为降低介电常数之反应型改质剂，与P-FBz混成，证实可有效地降低Poly的介电常数。

Isopropyl 1,3 benzodioxolane was synthesized from catechol and isobutyric aldehyde using the phosphotungstic acid supported on activated carbon as catalyst.

以邻苯二酚和异丁醛为原料，活性炭固载磷钨酸为催化剂合成了杀虫剂呋喃丹的中间体2 -异丙基- 1，3-苯并二氧五环。

The stereochemical structures of two new compounds, 5-(3-chlorophenyl)-2-furfur-aldehyde-N-4-methylphenyloxyacetylhydrazone and 5-(3-chlorophenyl)-2-furfuraldehyde-N-4-nitrophenyloxyacetylhydrazone, were determined by DPFGSE-NOE experiments performed in DMSO-d\-6 at 25 ℃ and variable-temperature ~1H NMR The ~1H chemical shifts of the compounds were completely assigned at 25 ℃ and 90

利用变温实验和DPFGSE NOE实验，确定了 5 (3 氯苯基) 2 呋喃甲醛 N 4 甲基苯氧乙酰腙和5 (3 氯苯基) 2 呋喃甲醛 N 4 硝基苯氧乙酰腙两个新化合物25 ℃时在二甲基亚砜中的空间构型，并对这两个新化合物在 25 ℃和 90 ℃时的质子的化学位移进行了全归属。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。