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Phenobarbital sodium induces differentiation and susceptibility to HBV in primary culture of early human fetal hepatocytes.

适当浓度的苯巴比妥钠可以促进孕10周龄人胎肝细胞分化成熟,并诱导HBV易感性的出现。

These ingredients includes epidermal growth factor, hepatocyte growth factor, dimethyl sulfoxide, phenobarbital sodium and all trans-retinoic acid. We isolate and culture primary 10-weeks-old human fetal hepatocytes, observe hepatocytes form and its function markers. Inoculate hepatocytes with HBV Dane particles to observe if HBV susceptibility of fetal hepatocytes can be induced in vitro. To detect HBV covalently closed circular DNA within hepatocytes, we improve the existent PCR method.

基于上述假设,我们设计了10种培养条件,在自行设计的无血清培养基中添加不同的细胞分化诱导物,包括表皮生长因子、肝细胞生长因子、二甲基亚砜、苯巴比妥钠、全反式维甲酸等,分离孕10周龄人胎肝细胞进行原代培养,观测肝细胞形态及功能指标变化,并定时给予HBV感染,观察能否在体外诱导胎肝细胞出现HBV易感性;为检测肝细胞内HBV共价闭合环状DNA(covalently closed circular DNA,cccDNA),我们改进了现有的PCR检测法。

objective:to prepare children's dispersible phenobarbital tablets and establish the method for its quality control.

摘 要 目的:制备小儿苯巴比妥分散片并建立质量控制方法。

Phenobarbital can manage and stabilize the state of intracranial hemorrhage in newborns and contribute to restoration and prognosis.

苯巴比妥能控制并稳定新生儿颅内出血的病情,对转归和预后有一定作用。

Methods: The treatment group of 46 newborns was administrated with phenobarbital to resist convulsions and keep calm.

治疗组46例患儿用苯巴比妥抗惊厥镇静,对照组40例用其他抗惊厥药物治疗并跟踪对比观察。

In patients with hepatic damage, phenobarbital should be administered with caution and initially reduced doses.

肝损病人应谨慎使用苯巴比妥,并应减少初始剂量。

A drug,C17H19ClN2S,derived from phenothiazine and used to suppress vomiting and as a sedative and a tranquilizer,especially in the treatment of schizophrenia and other psychotic states.

氯丙嗪一种药物,C17H19ClN2S,从苯硫醯胺制得,可抑制呕吐并可作为镇静剂和镇定剂,尤指用于治疗精神分裂症和其他精神异常状态

Production, consumption, and market s of L -phenylalanine at home and abroad are reviewed and ana-lyzed.

综述了国内外L-苯丙氨酸的生产和消费情况,并对其进行市场分析。

The adsorption of dimethyl phthalate in the soil is studied,and the influence of some factors, such as pH value and ionic strength on the adsorption is investigated.

对邻苯二甲酸二甲酯在内蒙古粘土中的吸附特征进行了研究,并观察了pH值和离子强度等因素对吸附作用的影响。

Moreover, one novel photochromic compound: 3,3-bis(4-methoxybenzyl)-3H-naphtho[2,1-b]pyran has been synthesized, which may be used in optical lenses to protect human eyes from being damaged by ultraviolet lights.

该化合物具有较好的光致变色性质,其开环式的颜色与吡啶并苯恶嗪的颜色互补,这两种化合物相结合构成第二代Transitions镜片的基础。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。