苯并

The results showed that: low molecular weight aromatic, such as naphthalene, fluorene, acenaphthene, locates at low levels, while the high molecular weight aromatic locates at high levels, such as benzo perylene, indene [1,2,3-cd] pyrene, benzo fluoranthene and benzo pyrene, of which , the concentration of fluoranthene is highest, reaching about 19%.

结果表明：萘、芴、苊等低分子量芳烃的含量相对较低；苯并苝、茚并[1，2，3-cd]芘、苯并荧蒽、苯并芘等高分子量芳烃的含量相对较高；含量最高的单体为荧蒽，占待检的16种PAHs的19%以上。

In this thesis, two series compounds of thiadiazole (2a~2f) and benzothiazole (5a~5f) were synthesized by using the reagent of iodobenzene diacetate. We also bound the iodobenzene diacetate reagent to the resin and applied it to synthesize thiadiazole and benzothiazole compounds.

本文利用二醋酸碘苯试剂分别与1-芳甲酰基-5-芳基-2-硫代缩二脲及1-芳甲酰基-3-芳基硫脲反应合成了噻二唑(2a~2f)和苯并噻唑(5a~5i)两个系列的杂环衍生物，并通过把二醋酸碘苯负载在高分子上合成了一类新型的固相氧化剂，同时考查了该固相氧化剂在噻二唑，苯并噻唑类化合物合成中的应用以及该固相氧化剂的循环使用。

Based on the problem of various types of catalyst and according to the features of carbonylation catalysts reactions, our team has been designed a series of new metal complexes of benimidazoles, which can be used for carbonylation catalyst of industry. Seven new benzimidazole derivatives were prepared by the o-phenylenediamine、oxalic acid、glycolic acid、monomethyl monopotassium malonate、ethyl cyanoacetate、succinic anhydride. The structures of them were confirmed by IR、Elemental analsis. The crystal structures of d and e were determined by X-ray single crystal diffraction of Germanic Bruker Smart APEX II CCD. The catalysis of them was tested by carbonylation reactions.

本文设计以邻苯二胺和草酸、羟基乙酸、丙二酸单甲酯、氰基乙酸乙酯、丁二酸单甲酯为原料采用PPA催化和无机酸催化法，合成了4种苯并咪唑-2-羧酸衍生物并进行了表征；培养了2个化合物d、e的晶体并测定和讨论了晶体结构；制备了3种未见报道的苯并咪唑金属配合物，对配合物在羰基化法制醋酐-醋酸反应的催化作用进行了初步试验。

Photoinduced Electron Transfer [2+2] Cycloaddition Reactions ofBenzannelated Isoquinolin-1-ones with Electron Deficient Alkenes Photoinduced [2+2] cycloaddition reactions of 11H-benzoxazolo[3,2-b]isoquinolin-11-one 8 and 11H-benzothiazolo[3,2-b]isoquinolin-11-one 13 with electron deficient alkenessuch as acrylonitrile, methyl acrylate, dimethyl fumarate and dimethyl maleate afforded a group of polycyclic isoquinoline derivatives bearing cyclobutane moieties ingood to excellent yields and resulted in the Schenck isomerization of the alkenes.

3苯并增环异喹啉-1-酮与缺电子烯烃的光诱导电子转移[2+2]环加成反应 11H-苯并恶唑[3，2-b]异喹啉-11-酮8和11H-苯并噻唑[3，2-b]异喹啉-11-酮13与缺电子烯烃如丙烯腈，丙烯酸甲酯，富马酸二甲酯及马来酸二甲酯的光诱导[2+2]环加成反应以高产率给出一系列含有环丁烷结构单元的多环异喹啉衍生物并导致烯烃的Schenck异构化作用。

An unreported compound 2-cyclopropylbenzimidazolium salt was obtained from 2-cyclopropyl benzimidazole and iodomethane.

以邻苯二胺和环丙基甲酸为原料，以多聚磷酸为催化剂，在微波辐射下合成了环丙基苯并咪唑，用碘甲烷季胺化得到未见文献报道的环丙基苯并咪唑盐，通过苯并咪唑盐与Grignard试剂加成后水解反应制备环丙基甲基酮。

Simultaneously we prepared benzimidazolines with two methods by the reducton of benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 9 kind of tetrahydro-β-carboline starting from carboxylic aicd and halid. A convenient synthetic method for preparing tetrahydro-β-carboline was provided.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了9种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以色胺作为接受一碳转移的亲核试剂，完成9种四氢-β-咔啉类化合物的新合成方法研究。

In this study, new benzo[l,2,3]thiadiazole derivatives were designed according to relationship of structure and efficacy. The 9 novel compounds were synsthesized with following reactions. The chlorine atom in 2-chloro-3,5-dinitro-benzoic acid as beginning raw material was substituted by 2-methylpropane-2-thiol, esterified then with bromoethane, reduced by iron powder and cyclized to obtain ethyl benzo[l,2,3]thiadiazole-7 after diazonation reation.

本论文根据苯并噻二唑诱导剂的构效关系设计了新的苯并噻二唑的结构，并合成了9个未见文献报道的化合物，合成步骤如下：采用2-氯-3，5-二硝基苯甲酸为起始原料，苯环上的氯原子被叔丁基硫醇置换，羧酸由溴乙烷酯化，硝基由铁粉还原，随后经重氮化关环生成苯并[1，2，3]噻二唑-7-羧酸乙酯。

Simultaneously we prepared benzimidazolines with two methods by the of reduction benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 13 kind of tetrahydroisoquinoline starting from carboxylic aicd and halid, gave a new idea of the synthesis for new drugs.It can make many kind ofβ-carboline alkaloids which have bioactivity to antibacterium, antivirus and antitumor to start from 1,2,3,4-tetrahydro -β-carboline.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了13种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以2-(3，4-二甲氧基苯基)乙胺作为接收一碳转移的亲核试剂，完成了13种重要的四氢异喹啉类化合物的新合成方法研究。

The best of them were 4c and 8d which exhibited 87% and 89% inhibition of Penicilium digitatum . And benzothieno[3,2-d]imidazol[1,2-a]pyrimidin-2,5(1H, 3H)-diones or benzothieno[3,2-d][1,2,4]triazol[1,5-a]pyrimidin-10(3H)-one only exhibited moderate inhibition.

而苯并噻吩并[3，2-d]嘧啶-4(3H)-酮和苯并噻吩并[3，2-d]咪唑并[1，2-a]嘧啶-2，5(1H，3H)-二酮以及苯并噻吩并[3，2-d][1，2，4]三唑[1，5-a]嘧啶-10(3H)-酮衍生物以及三唑醇衍生物均只表现出中等的抑制率。

And benzothieno[3,2-d]imidazol[1,2-a]pyrimidin-2,5(1H, 3H)-diones or benzothieno[3,2-d][1,2,4]triazol[1,5-a]pyrimidin-10(3H)-one only exhibited moderate inhibition.

而苯并噻吩并[3，2-d]嘧啶-4(3H)-酮和苯并噻吩并[3，2-d]咪唑并[1，2-a]嘧啶-2，5(1H，3H)-二酮以及苯并噻吩并[3，2-d][1，2，4]三唑[1，5-a]嘧啶-10(3H)-酮衍生物以及三唑醇衍生物均只表现出中等的抑制率。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。