苯并

But in the + moiety, the three benzimidazole rings shared the whole space equally, the dihedral angel among them is about 120°, just like three fan blades of an airscrew, the molecular structure appear gear-like shape.

X-射线单晶衍射测试、红外、紫外等方法确定了三(2-苯并咪唑亚甲基)胺的Fe和Co配合物的结构，由晶体结构发现金属配位情况不同、配合物在结构上存在着差异，Fe为八面体构型，而Co为三角双锥构型；其次，两配合物中的苯并咪唑环间夹角不同，配合物中包含N2和N4的两个苯并咪唑环间夹角仅为9.41(0.11)，几乎构成一个平面，呈蝴蝶形；后者Co三个苯并咪唑环几乎平分了整个空间，它们之间的夹角约为120，呈三扇叶螺旋桨式构型，为齿轮形。

Experimental process: jing and 3- methyl -2- methyl ethyl ketonesynthesizes by the benzene zong; Again the glacial acetic acidcatalysis produces 2, 3, 3 - trimethyl - 3H - yinduo; Again has thealkylate response production yinduo iodide after the methyl iodide;The iodide takes off molecular HI under NaOH to become freejier thealkali; Adds 5 - nitryls salicylic aldehydes in the ethyl alcohol forthe solvent under if to respond finally produces 6 '- the nitryl yinduolin spiral benzene and pinan; Through the infrared spectrum andthe ultimate analysis irrevocably proved its structure, and studiedthe annulus with to open the annulus the light to send changes colorthe performance, explained in different solvent medium ultravioletabsorption spectrometry solvent effect, and the comparisondiscoloration the response speed number difference, finally mixed itadds to the methyl methacrylate, the peroxidation benzoin formyl in the plexiglass, tested 6 '- the nitryl yinduolin spiralbenzene and pinan in the glass fatigue resistance, thethermostability.

实验过程：由苯肼和3-甲基-2-丁酮合成腙；再冰醋酸催化生成2 ，3 ，3—三甲基—3H—吲哚；再经过碘甲烷发生烷基化反应生成吲哚碘化物；碘化物在NaOH下脱去一分子HI成为费歇尔碱；在乙醇为溶剂下加5－硝基水杨醛与其反应最后生成6'—硝基吲哚啉螺苯并吡喃；通过红外光谱和元素分析确证其结构，并研究了环体与开环体的光致变色性能，解释了在不同溶剂介质中紫外吸收光谱的溶剂效应，并比较褪色反应速率数的差异，最后将其掺加到甲基丙烯酸甲酯，过氧化二苯甲酰有机玻璃中，测试6'—硝基吲哚啉螺苯并吡喃在玻璃中的抗疲劳性、热稳定性。

The initial SAR studies indicated:(1) the presence of a linker of methene at the N-1 may be beneficial to anti-HIV activity, while longer chain could enhance toxicity;(2) substituted phenyl at the C-2 could reduce toxicity;(3) 6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4) the presence of a halogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

The initial SAR studies indica ted:(1)the presence of alinker of methene at the N-1may be beneficial to anti-HIV activity,while longer chain could enhance toxicity;(2)substituted phenyl at the C-2could reduce toxicity;(3)6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4)the presence of ahalogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

The studies are significant to propose the synthetic methodology of benzothiazole derivatives,broaden the application of the metal complexes of benzothiazoles.It is practical value of the research in preparation of phenylacetic acid from metal-catalyized carbonylation.The thesis consists of four chapters.

本论文研究了苯并噻唑衍生物及其钴、铑金属配合物的合成，并研究了两类金属配合物的羰基化催化性能，提供了合成苯并噻唑衍生物的可行路线，拓宽了苯并噻唑金属配合物的应用范围，催化羰基化合成苯乙酸的研究具有重要的实用价值。

We firstly introduced benzoazole (including benzimidazole, benzoxazole and benzothiazole) into the meso-positions of porphines and obtained five new porphyrins 36a-e. Their structures were characterized by 1H NMR, MS, UV-vis spectra and fluorescence emission spectra.

将苯并唑类基团(苯并咪唑、苯并噁唑和苯并噻唑)引入到卟吩中位，得到5个新型卟啉36a-e衍生物，并经核磁氢谱、质谱、紫外吸收光谱和荧光发射光谱表征了化合物的结构。

The results showed that loading Ag^＋, Ni^2＋, Cu^2＋ or Zn^2＋ ion on the activated carbon obviously improved its adsorption of benzothiophene, while loading Fe^3＋ or Co^3＋ ion on the activated carbon caused a decrease in its adsorption of benzothiophene in comparison with the original unloaded activated carbon, which was due to the variation of the nature of soft and hard acid on the surface of the activated carbon.

采用密度泛函数理论法计算结果表明，苯并噻吩的电负性χ为2.638，属软碱类物质；由于Ag^＋为软酸，活性炭负载Ag^＋离子，增加了其局部表面的软酸，从而增强了对苯并噻吩硫化物的吸附；由于Ni^2＋、Cu^2＋和Zn^2＋离子属交界酸，负载Ni^2＋、Cu^2＋、Zn^2＋离子增加了活性炭表面的交界酸，也在一定程度上提高了其表面对苯并噻吩硫化物的吸附；当活性炭表面负载了硬酸性Fe^3＋或Co^3＋离子，其局部表面硬酸增大从而降低了其对苯并噻吩的吸附。

Three kinds of small molecular copper and zinc superoxide dismutase mimics were synthesized with N, N-bis (benzimidazol-2-ylmethyl) amine (N3), N, N-bis (benzimidazol-2-ylmethyl) methylamine(MN3) and N,N-bis (benzimidazol-2-ylmethyl) benzylamine(BN3) as ligands. The com-plexes were characterized by UV, IR and element analysis and the structures were proposed.

模拟铜一锌超氧化物歧化酶的活性中心，以二(2-苯并咪唑)丙烷为桥、二(2-苯并咪唑亚甲基)胺(N3)、二(2-苯并咪唑亚甲基)甲胺(MN3)及二(2-苯并咪唑亚甲基)苄胺(BN3)为配体合成了3种异双核的小分子模型化合物，并进行了紫外、红外表征及元素分析，推测了可能的结构。

Two novel A-it-A' type benzothiazole-based derivatives with benzothiazolyl, phenyl-acetyl or pyridine cation groups as π electron acceptor, diethenylphenyl as π conjugated bridge: 4-(2-benzothiazolyl) ethenylchalcone (1) and 4-{4-[2-(benzothiazole-2-yl) ethenyl] styryl}-N-methylpyridinium iodide (2) were synthesized.

以苯并噻唑、苯乙酰基和吡啶阳离子为电子受体，二乙烯基苯为共扼桥，合成了两个新的A-π-A'型苯并噻唑衍生物：4-（2-苯并噻唑）－乙烯基查尔酮(1)和4-｛4-［2-乙烯基］苯乙烯基｝－N-甲基吡啶碘盐(2)。

Two novel A-π-A′ type benzothiazole-based derivatives with benzothiazolyl,phenyl-acetyl or pyridine cation groups as π electron acceptor,diethenylphenyl as π conjugated bridge: 4-(2-benzothiazolyl)ethenylchalcone(1) and 4-{4-[2-(benzothiazole-2-yl)ethenyl]styryl}-N-methylpyridinium iodide(2) were synthesized.

以苯并噻唑、苯乙酰基和吡啶阳离子为电子受体，二乙烯基苯为共轭桥，合成了两个新的A-π-A′型苯并噻唑衍生物：4-(2-苯并噻唑)-乙烯基查尔酮(1)和4-{4-[2-乙烯基]苯乙烯基}-N-甲基吡啶碘盐(2)。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。