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苯巴比妥

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Solid phase extraction and gas chromatography-mass spectrometric method have been ~developed for the determination of barbital, amobarbital and phenobarbital residues in pork.

采用HP5毛细管柱分离,电子轰击电离源质谱选择离子模式检测(巴比妥m/z126,169,183,184;异戊巴比妥m/z169、170、184、226;苯巴比妥m/z175、232、245、260;dwelltime80s),外标法定量(定量离子m/z分别为169、169和232)。

Objective To establish an animal model of refractory epilepsy by peritoneal injection of phenytoin sodium and phenobarbital sodium, and investigate into their multidrug resistance mechanism in kindling rats.

目的 探索性应用苯妥英钠、苯巴比妥钠诱导建立难治性癫疒间动物模型,并研究其多药耐药机制。

Results: The percentages of patients with serum drug concentrations within the effective ranges after single first-line antiepileptic treatment were significantly different (P.01), with sodium valproate, phenobarbital, carbamazepine and sodium phenytoin being 75.2%, 67.3%, 53.1% and 20.8%, respectively.

结果:各药在有效血药浓度范围内的病例百分率差异显著(P.01),分别为丙戊酸钠75.2%、苯巴比妥67.3%、卡马西平53.1%、苯妥英钠20.8%。

Objective: To explore the effect of intramuscular injection of midazolam before intravertebral anesthesia on sedation luring operation and amnesia after operation. Methods: Selected 180 ASA cases at 1~2 stage with lower extremity surgery under combined spinal and epidural anaesthesia, and randomly divided them into midazolam group and phenobarbital sodium group. Gave patients in midazolam group intramuscular injection of midazolam at 0.1mg/kg 10 min earlier before operation, while gave patients in phenobarbital sodium group 0.1 g phenobarbital sodium 30 mm earlier.

目的:探讨椎管内麻醉前肌注咪唑安定对术中的镇静作用和对术后遗忘的影响:方法:选择ASA1~2级择期在腰硬联合阻滞下行下肢手术的患者180例,随机分为咪唑安定组和苯巴比妥钠组,咪唑安定组患者入室后(实施麻醉前10min)肌内注射咪唑安定0.1mg/kg,苯巴比妥钠组患者入室前30min肌内注射苯巴比妥钠0.1g。

Gave patients in midazolam group intramuscular injection of midazolam at 0.1 mg/kg 10 min earlier before operation, while gave patients in phenobarbital sodium group 0.1 g phenobarbital sodium 30 min earlier. With Ramsay sedation evaluation assessed mean arterial pressure and heart rate during anesthesia, before and after operation, respectively.

选择ASA1~2级择期在腰硬联合阻滞下行下肢手术的患者180例,随机分为咪唑安定组和苯巴比妥钠组,咪唑安定组患者入室后(实施麻醉前10 min)肌内注射咪唑安定0.1 mg/kg,苯巴比妥钠组患者入室前30 min肌内注射苯巴比妥钠0.1 g。

Abstract] Objective:To study the effect of phenobarbital in curing intracranial hemorrhage in newborn.

内容摘要:苯巴比妥;颅内出血;新生儿[摘要]目的:探讨苯巴比妥在治疗新生儿颅内出血中的作用。

Result: The ideal separation for phenytoin, carbamazapine and phenobarbital was obtained within 5 min.

结果:三种常用抗癫痫药物卡马西平,苯巴比妥,苯妥英钠在5 min之内获得了理想的分离。

Phenobarbital is contraindicated in patients with known phenobarbital sensitivity or a history of manifest or latent porphyria.

苯巴比妥过敏、有征候性或潜伏性卟啉病史者禁用苯巴比妥

Phenobarbital does not impair normal hepatic function but has been shown to induce liver microsomal enzymes, thus increasing and/or altering the metabolism of barbiturates and other drugs.

苯巴比妥不损害肝脏的功能,但可诱导肝微粒体酶,从而增加或改变巴比妥类和其他药物的代谢。

The electrical activity of Ⅻ nerve rootlets and inspiratory neurons were recorded.

在改良Krebs液中分别单独加入巴比妥类药物苯巴比妥钠,终浓度分别为20、40、60、80μmol/L,持续灌流1h,观察舌下神经根RRDA及吸气神经元单位电活动的变化。

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