苯妥英

Objective: To study the anticonvulsive action of scorpion alcoholic extraction on phenytoin-resistant convulsive rats made by direct cortical electrical stimulation in order to investigate the mechanism of antagonizing drug-resistance of SAE.

中文摘要：目的：研究全蝎乙醇提取物(scorpion alcohol extraction，SAE)对电刺激大脑皮层点燃耐苯妥英钠大鼠惊厥模型的对抗作用，并探讨其抗耐药作用机制。

For that disease's treatment, modern internal medicine always use the medicines as central anticonvulsive drug and periph anticonvulsive drug,such as baclofen、botulinum toxin type A、Myonal、Dantrolene、Diphenylhydantoin sodium.

针对本病，现代医学内科治疗方面，在药物选择上有中枢解痉药和外周解痉药，如巴氯酚、A型肉毒毒素、妙纳、丹曲林、替尼扎定、苯妥英钠等。

Result: Both doses of SAE and verapamil ig all raised the convulsant threshold of phenytoin-resistant rats (480.38±18.48)μA, there were statistical differences ( P .05) compared to themselves before drugs-treated.

结果：全蝎乙醇提取物2种剂量及维拉帕米，均可使耐苯妥英钠大鼠惊厥阈值(480.38±18.48)μA明显升高，与惊厥模型组和耐苯妥英钠惊厥模型组相比均有显著性差异( P 。01)。

Made arrhythmia models of rats by injecting digitoxin,then treated then by injecting nifedipine and compared then with phenytoxin sodium group. Result Nifedipine can not cure arrhythmia,instead making it worse.

注射洋地黄建立大鼠心律失常模型，分别注射硝苯地平治疗，并与注射苯妥英钠组进行比较结果：硝苯地平不能治疗心律失常，反而使心律失常加重。

Objective To establish an animal model of refractory epilepsy by peritoneal injection of phenytoin sodium and phenobarbital sodium, and investigate into their multidrug resistance mechanism in kindling rats.

目的 探索性应用苯妥英钠、苯巴比妥钠诱导建立难治性癫疒间动物模型，并研究其多药耐药机制。

Results: The percentages of patients with serum drug concentrations within the effective ranges after single first-line antiepileptic treatment were significantly different (P.01), with sodium valproate, phenobarbital, carbamazepine and sodium phenytoin being 75.2%, 67.3%, 53.1% and 20.8%, respectively.

结果：各药在有效血药浓度范围内的病例百分率差异显著(P.01)，分别为丙戊酸钠75.2%、苯巴比妥67.3%、卡马西平53.1%、苯妥英钠20.8%。

Result: The ideal separation for phenytoin, carbamazapine and phenobarbital was obtained within 5 min.

结果：三种常用抗癫痫药物卡马西平，苯巴比妥，苯妥英钠在5 min之内获得了理想的分离。

For example, an uncomplicated urinary tract infection may be cured with a sulfonamide, whereas a patient with grand mal epilepsy may have to be treated for life with phenytoin or phenobarbital or both.

例如，无并发症的尿道感染用一种磺胺药物治疗10天就可能痊愈，而患有大发作的癫痫病人则须用苯妥英钠或苯巴比妥或两药合用作终身治疗。

Neomycin on ammonia acid can lead to vitamin B12 deficiency; phenytoin, methotrexate, B ammonia pyrimidine, methyl benzyl ammonium pyrimidine and Triamterene, etc. can cause folic acid deficiency; mercaptopurine, 5 - fluoro-piperidine urine density, Ara-C, etc. can interfere with nucleic acid synthesis, these drugs can lead to megaloblastic anemia.

新霉素、对氨水杨酸可导致维生素B12缺乏；苯妥英钠、甲氨蝶呤、乙氨嘧啶、甲基苄氨嘧啶及氨苯蝶啶等可引起叶酸缺乏；巯嘌呤、5--氟尿密啶、阿糖胞苷等能够干扰核酸的合成，这些药物都可导致巨幼红细胞性贫血。

METHODS: The serum concentration of valproic acid、diphenylhydantoin、carbamazepine、phenobarbital by HPLC.

采用高效液相色谱法(High performance liquid chromatography ，HPLC)测定丙戊酸、苯妥英钠、卡马西平、苯巴比妥的血药浓度785例，并对结果进行分析。

My first article for Screen Power Magazine, which is to this day is the official magazine of Jackie Chan, was a DVD review of the Hong Kong actioner Gen-X Cops, starring Nicholas Tse and Daniel Wu.

我的第一篇文章为屏幕力量杂志，在对这天是Jackie Chan 正式杂志，是香港actioner Gen X 警察的DVD 回顾，担任主角Nicholas Tse 和丹尼尔吴。

His lips grazed hirs, Now what are you going to do?

他的唇使吃草了 hirs，现在你将要做什麼？