苯基甘氨酸

The course of reaction was monitored by estimating the amount of isopropanol liberated in benzene-isopropanol azeotrope in each case.

合成是在苯溶液中采用了金属/非金属的异丙氧基化合物和N-(2-甲基)苯基甘氨酸按1：1和1：2的配比完成的。

The chiral guanidine —compound(6)was synthesized from the methyl-phenylglycinate hydrochloride as material and the reaction conditions were investigated.

本文以-苯基甘氨酸甲酯盐为原料合成了手性胍—化合物(6)，并对合成反应条件进行了探索和优化。

Therelationship of the amount of catalyst and the ee% of product was seen to be negative nonlin-ear. Catalyst 3 was used in the enantioselective addition of diethylzinc to aromatic aldehydesand gave good results. The configuration of products was determined by the configuration ofthe catalysts' chiral carbon linked with hydroxy group. Using β- amino alcohols bearing only one chiral center as catalysts for the enantiose-lective addition were studied. D-N, N-dialkyl-2-amino butanol gave poor catalytic effect be-cause of their structure. The configuration of the product is the same as the catalyst. Anotherkind of β- amino alcohols - phenylglycine derivatives and valine derivatives have chiralcenter on the carbon linked with amino group. Catalyzed by-phenylglycine derivatives 6,7, 9, 10, the reactions gave satisfied results. The optical yields exceeded 80%.

在探讨了含有两个手性中心的β-氨基醇之后，选择了只有一个手性中心的β-氨基醇，一是手性中心为连羟基的手性碳原子：D-N，N-二烷基-2-氨基丁醇；二是手性中心为连氨基的手性碳原子：D-苯基甘氨酸衍生物和L-缬氨酸衍生物。D-2-氨基丁醇的催化效果不太好，这与其结构的空间位阻较小有关系，反应产物与连羟基手性碳构型一致；由苯基甘氨酸和缬氨酸出发合成五种β-氨基醇6-10，研究了不同ee％的-6作用下的二乙基锌-苯甲醛加成反应，发现该催化剂具有不对称放大效应；-7，9，lO的催化效果也比较令人满意，光学产率80％以上，所得产物构型与催化剂构型一致。

Several trivalent (boron, aluminium, iron, arsenic and antimony) and tetravalent metal/non-metal derivatives of N-(2-methyl) phenylglycine have been prepared by the interaction of their corresponding isopropoxide with the latter in 1:1 and 1:2 molar ratios in benzene medium.

用N-(2-甲基)苯基甘氨酸合成了几种及四价金属/非金属衍生物。

A compound 2-(3-hydroxyphenyl)[60] fullerene pyrrolidine was synthesized by the 1,3-dipolar cycloaddition reaction of the fullerene(C60) and azomethine ylide (prepared from glycine and 3-hydroxybenzaldehyde). The product was characterized by UV-Vis,1H-NMR ,FT-IR and MS. The reaction conditions affecting the yields of product were investigated and the optimum reaction conditions with product yield 75%(based on consumed C60) were:molar ratio of C60∶3-hydroxybenzaldehyde:glycine 1∶3∶6,reaction temperature 95℃,reaction time 18h.

利用甘氨酸和3-羟基苯甲醛与C60发生1， 3-偶极环加成反应，合成分离得到了2-(3-羟基苯基)[60]富勒烯吡咯烷，用UV-Vis、1H-NMR、FT-IR、MS等测试手段表征了产物的结构，并通过单因素方法，探讨了反应条件对产物产率的影响，得到最佳工艺条件：反应物摩尔比1∶3∶6，温度95 ℃，反应时间18 h，产物的产率可达75%（以消耗的C60计）。

Resolution of benzoin,hydrobenzoin and α- phenethyl alcohol with-phenylglycine based chiral stationary phase(Chirex 3001)in the normal-phase conditions were studied.

正相模式下研究了安息香、氢化安息香及α-苯乙醇在苯基甘氨酸型手性固定相Ch irex 3001上的拆分，探讨了流动相组成及柱温对手性拆分效果的影响。

Employing CuI(5 mol%), N,N-dimethylglycine hydrochloride(10 mol%) and K_2CO_3(2 equiv.) in refluxing THF as the optimized reaction conditions,the four-membered 4-alkylidene-2-azatidinones could be efficiently synthesized.

当以3-溴-3-N-苯基-丁烯酰胺为底物，在5 mol%CuI为催化剂，10 mol%N，N-二甲基甘氨酸盐酸盐为配体，2当量K_2CO_3作碱，THF回流的反应条件下，可以高效的合成2-亚甲基-4-氮杂环丁酮类化合物。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。