苯亚甲基

Methods 4-Hydroxy- benzonitrile was treated with sodium hydrogen sulfide and anhydrous magnesium chloride in dimethyl formamide to give thioamide, which was then directly cyclized with ethyl 2-chloroacetoacetate without separation to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(2) in one-pot; then 2 was formylated with Duff reaction adopting hexamethylenetetramine in trifluoroacetic acid to give ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(3); finally, the target compound was obtained by the treatment of 3 with hydroxylamine hydrochloride and sodium formate in formic acid.

采用"一勺烩"方法，以4-羟基苯甲腈为起始原料，首先与硫氢化钠和无水氯化镁在N，N-二甲基甲酰胺中反应，所得中间体不经分离，直接加入2-氯乙酰乙酸乙酯进行环合反应，得到2-(4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（2）；然后通过六亚甲基四胺/三氟乙酸进行Duff反应，得到2-(3-甲酰基-4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（3）；再经盐酸羟胺/甲酸/甲酸钠体系脱水得到目标化合物。

In our research on study chemical reaction of active methylene compounds and brom-acetophenone. Because of brom-acetophenone is compound that contain carbonyl and halogen ,which will take place electrophilic substitution and nucleophilic addition. When active methylene compounds are ethyl acetoacetate and β-diketone, controlling reaction condition, we have found that mono-substitution's production and di-substitution's. production is isolated; active methylene compounds are acetoacetanilide and acetoacetanilide derivate, pyrrolidin-2-one derivants were obtained by substitution and close-ring reaction .but there is no report about it.

本文是让活泼亚甲基类化合物与溴代苯乙酮发生化学反应，由于溴代苯乙酮是含有羰基的卤代烃结构，它可以发生亲电取代和亲核加成反应，当活泼亚甲基类化合物为乙酰乙酸乙酯和β-二酮时，控制反应条件可以发生单取代和双取代两种产物；当活泼亚甲基类化合物为乙酰乙酰芳胺类化合物来反应时，溴代苯乙酮中的羰基与氨基会发生分子内的关环反应生成吡咯烷-2-酮衍生物，这在以前的研究中是没有发现的。

The other for: safrole, sassafras oil, safrole different 82 yuan / kg; 1 - phenyl -2 - propanone 2,500 yuan / kg; 3.4 dioxane methylene diphenyl -2 - propanone 7200 yuan / ton; Piperonal 1,000 yuan / kg; N-acetyl-o-amino benzoic acid 11500 yuan / ton; anthranilic acid 15,500 yuan / ton; Phenylacetate 15,000 yuan / ton; acetic anhydride 9900 yuan / ton; trichloromethane 4100 yuan / ton ; anhydrous ether 8500 yuan / ton; piperidine 58000 yuan / ton; methyl ethyl ketone 10,000 won / ton; sulfate 1,200 yuan / ton; hydrochloride 400 yuan / ton; ethanol 4200 yuan / ton.

另供：黄樟素、黄樟油、异黄樟素82元/公斤；1-苯基-2-丙酮2500元/公斤；3.4 亚甲基二氧苯基-2-丙酮7200元/吨；胡椒醛1000元/公斤；N-乙酰邻氨基苯酸11500元/吨；邻氨基苯甲酸15500元/吨；苯乙酸15000元/吨；醋酸酐9900元/吨；三氯甲烷4100元/吨；无水乙醚8500元/吨；哌啶58000元/吨；甲基乙基酮10000元/吨；硫酸1200元/吨；盐酸400元/吨；无水乙醇4200元/吨。

The other for: safrole, sassafras oil, safrole different 82 yuan / kg; 1 - phenyl -2 - propanone 2,500 yuan / kg; 3.4 dioxane methylene diphenyl -2 - propanone 7200 yuan / ton; Piperonal 1,000 yuan / kg; N-acetyl-o-amino benzoic acid 11500 yuan / ton; anthranilic acid 15,500 yuan / ton; Phenylacetate 15,000 yuan / ton; acetic anhydride 9900 yuan / ton; trichloromethane 4100 yuan / ton ; anhydrous ether 8500 yuan / ton; piperidine 58000 yuan / ton; toluene 5200 yuan / ton; methyl ethyl ketone 10,000 won / ton; sulfate 1,200 yuan / ton; hydrochloride 400 yuan / ton; anhydrous Ethanol 4200 yuan / ton.

另供：黄樟素、黄樟油、异黄樟素82元/公斤；1-苯基-2-丙酮2500元/公斤；3.4 亚甲基二氧苯基-2-丙酮7200元/吨；胡椒醛1000元/公斤；N-乙酰邻氨基苯酸11500元/吨；邻氨基苯甲酸15500元/吨；苯乙酸15000元/吨；醋酸酐9900元/吨；三氯甲烷4100元/吨；无水乙醚8500元/吨；哌啶58000元/吨；甲苯5200元/吨；甲基乙基酮10000元/吨；硫酸1200元/吨；盐酸400元/吨；无水乙醇4200元/吨。

Phthalimide,anthranilic acid,2methyleneglutaronitrile bromina 1bromobutane 1,2benzisothiazole3one.

邻苯二甲酰亚胺，邻氨基苯甲酸，2亚甲基戊二脯，2溴2溴甲基戊二脯，溴代正丁烷，1.2苯并异噻唑3酮。

Three kinds of small molecular copper and zinc superoxide dismutase mimics were synthesized with N, N-bis (benzimidazol-2-ylmethyl) amine (N3), N, N-bis (benzimidazol-2-ylmethyl) methylamine(MN3) and N,N-bis (benzimidazol-2-ylmethyl) benzylamine(BN3) as ligands. The com-plexes were characterized by UV, IR and element analysis and the structures were proposed.

模拟铜一锌超氧化物歧化酶的活性中心，以二(2-苯并咪唑)丙烷为桥、二(2-苯并咪唑亚甲基)胺(N3)、二(2-苯并咪唑亚甲基)甲胺(MN3)及二(2-苯并咪唑亚甲基)苄胺(BN3)为配体合成了3种异双核的小分子模型化合物，并进行了紫外、红外表征及元素分析，推测了可能的结构。

Tetrachloroterephthalic acid was prepared by chlorinating terephthalic acid, oleumsolvent and iodine catalyst. Tetrachloroterephthalic acid was acylated by sulphurous oxychloride in the presence of DMF to form tetrachloroterephthaloyl chloride. The acyl chloride product was fluorinated by potassium fluoride and esterified by methanol to synthesize dimethyl tetrafluoroterephthalate. The ester was reduced with potassium borohydride and lithium chloride to give tetrafluoroterephthalyl alcohol. The above product was bromated in the hydrobromic acid to obtain 4-bromomethyl-2,3,5,6-tetrafluoro-benzene methanol. 4-Methyl-2,3,5,-6-tetrafluorobenzene ethanol was obtained by reducing the bromide with magnesium. In the exist of DCC and DMAP, tefluthrin was got by the condensation reaction between 4-methyl-2,3,5,6-tetrafluoro-benzene methanol and-(1RS,3RS)- 3-(2- chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cycolpropanecar-boxylate acid.

对苯二甲酸与氯气在碘存在下以发烟硫酸为溶剂进行氯化制备四氯对苯二甲酸；再以DMF为催化剂与二氯亚砜反应生成四氯对苯二甲酰氯；以氟化钾为氟化剂，环丁砜为溶剂置换氟化，再与甲醇酯化得到四氟对苯二甲酸甲酯；以KBH4-LiCl为还原剂二甲醚为溶剂反应制得四氟对苯二甲基苄醇；以氯苯为溶剂在溴化氢溶液中溴化得到溴化产物；在乙醇溶液中经镁粉还原得到4-甲基-2，3，5，6-四氟苄醇；甲基苄醇与功夫酸在催化剂二环己基碳二亚胺和4-二甲氨基吡啶作用下缩合得到七氟菊酯，总收率达43.6%。

Phenylethyl than malonic acid methyl malonic acid benzene over a methylene, metal complexes of stability and performance is a lack of research.

苯乙基丙二酸比苯甲基丙二酸多一个亚甲基，其金属配合物的稳定性及性能尚缺乏研究。

Methods 4-Hydroxy- benzonitrile was treated with sodium hydrogen sulfide and anhydrous magnesium chloride in dimethyl formamide to give thioamide, which was then directly cyclized with ethyl 2-chloroacetoacetate without separation to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(2) in one-pot; then 2 was formylated with Duff reaction adopting hexamethylenetetramine in trifluoroacetic acid to give ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(3); finally, the target compound was obtained by the treatment of 3 with hydroxylamine hydrochloride and sodium formate in formic acid.

采用&一勺烩&方法，以4-羟基苯甲腈为起始原料，首先与硫氢化钠和无水氯化镁在N，N-二甲基甲酰胺中反应，所得中间体不经分离，直接加入2-氯乙酰乙酸乙酯进行环合反应，得到2-(4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（2）；然后通过六亚甲基四胺/三氟乙酸进行Duff反应，得到2-(3-甲酰基-4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（3）；再经盐酸羟胺/甲酸/甲酸钠体系脱水得到目标化合物。

Benzyl isopropyl ether also forms CCT complex with oxygen on the benzene ring like phenyl isopropyl ether, but it is easy to oxidize since charge transfer and 〓 transfer may occur at the methylene group adjacent to the benzene ring, which result in the oxidation of the methylene group.(4) The 〓-CCT complex and the initial dark oxidation mechanism of poly were studied.

虽然苄基异丙醚也以苯环与O〓形成CCT复合物，但它却容易发生暗氧化，这是由于与苯基相连的是亚甲基，此时电荷转移发生在苯环与亚甲基之间，引起亚甲基的氧化，而不是异丙基的氧化。

Now, however, all children continue in "comprehensive" schools, and the eleven-plus determines which courses of study the child will follow.

然而现在，所有的孩子都要在综合学校继续学习，所以这次考试只是决定他们将要学习哪些课程。

Cultivatable land , and led to a general recognition that development must not be carried at the cost of agriculture .

城区的迅速扩大在很多情况下侵占了宝贵的可耕地，使人们普遍认识到发展不能以牺牲农业为代价。