苯亚甲基

The Knoevenagel condensation reactions between aromatic and α,β-unsaturated aromatic aldehydes with barbituric acid can effectively be performed in ionic liquid without additional acid or base catalyst, it is a simple efficient method for the synthesis of benzylidene barbituric acids, which have been widely used in pharmaceutical chemistry as well as in organic synthesis.

芳醛、α，β-不饱和芳醛和巴比妥酸间的Knoevenagel缩合反应能在离子液体中没有酸碱催化剂的条件下顺利进行，是合成在药物化学和有机合成中有广泛用途的苯亚甲基巴比妥酸类化合物的简单有效的方法。

In this dissertation, synthesis of benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene]dichlororuthenium (41) has been improved.

本论文首先改进了钌卡宾配合物[1，3-二-(2，6-甲苯基)-4，5-二氢咪唑基]-苯亚甲基-三苯基膦-二氯合钌(41)的合成方法。

Title compounds were synthesized by condensation of 3 benzylidene isochroman 4 one with 5 substituted 4 amino 3 mercap to 4 1,2,4 triazoles.

通过异色满酮－4的3－位苯亚甲基取代衍生物与4－氨基－3－巯基－1，2，4－三唑的缩合反应得异色满并［3，4－f］硫氮杂奥。

Five types of compounds were synthesized via modification of the leading compounds, Mannich bases of cyclopentanones. Among the target compounds, one type was aromatic amine derivatives of a leading compound, three were Mannich bases of a - benzylidene cyclopentanone, the fifth was a Mannich base of a - benzyl cyclopentanone.

以具有抗炎活性的环戊酮Mannich碱为先导化合物进行结构改造，设计合成了一类已知化合物的芳胺Mannich碱衍生物，三类α-苯亚甲基环戊酮Mannich碱类化合物，一类α-苄基环戊酮Mannich碱类化合物。22个目标化合物的结构经核磁共振氢谱、红外光谱和质谱检测确证。

Sixteen target compounds were designed and synthesized, basing on 2--(4-hydroxy-3-methoxybenzylidene)cyclopentanone as the lead compound, all of which are innovative and have not been reported yet.

本文以2--(3-甲氧基-4-羟基苯亚甲基)环戊酮为先导化合物，设计并合成了16个目标化合物，均为未见文献报道的新化合物。

This dissertation is mainly focused on the reactivity of methylenecyclopropanes and comprises six parts. 1 The reactions of methylenecyclopropanes with phenylsulfenyl chloride, phenylselenyl chloride and diphenyl diselenide; 2 The coupling reactions of the ring-opening products derivated from methylenecyclopropanes; 3 The palladium-catalyzed ring-enlargement of mono-aryl group substituted methylenecyclopropanes to cyclobutenes. 4 The gold-catalyzed domino ring-opening and ring-closing hydroamination of methylenecyclopropanes with sulfonamides; 5 The Lewis acid-catalyzed reactions of mono-aryl group substituted methylenecyclopropanes with diethyl ketomalonate in the presence of water; 6 The iodobenzene diacetate mediated novel 1,3-dipolar cycloaddition of methylenecyclopropanes, vinylidenecyclopropanes, and methylenecyclobutane with phthalhydrazine.

本论文主要研究了亚甲基环丙烷类化合物的一些化学反应性能，共由以下六部分组成：1、亚甲基环丙烷类化合物与苯硫氯、苯硒氯及二苯基二硒的反应；2、亚甲基环丙烷类化合物开环产物的偶联反应；3、单芳基取代的亚甲基环丙烷类化合物在钯催化剂作用下的扩环反应；4、金化合物催化磺酰胺对亚甲基环丙烷类化合物的串联开环关环氨氢化反应；5、路易斯酸催化亚甲基环丙烷类化合物与丙酮二羧酸二乙酯在有水存在下的反应；6、醋酸碘苯促进的亚甲基环丙烷类化合物、亚乙烯基环丙烷类化合物及亚甲基环丁烷类化合物与邻苯二甲酰肼的新型1，3-偶极环加成反应。

One of these compounds, 2-diethyl- aminoethyl-5--(4-methoxybenzylidene) cyclo- pentanone hydrochloride (T81) possessed sig- nificant antiinflammatory and analgesic ac- tivity when administered orally.

Ⅲ类化合物完全无抗癌活性，对其中一个化合物2-二乙胺乙基-5--（4-甲氧基苯亚甲基）环戊酮盐酸盐（T81）试验结果表明，它经口给药时具有显著的抗炎、镇痛活性。

It was reported that benzylidenemalononitrile did not react with 1-benzyl-1,4-dihydronicotinamide. However, similar reaction easily takes place under the same condition when the phenyl group is replaced by the pyridyl group.

本课题组之前报道了苯亚甲基丙二腈在室温下不能被BNAH所还原，本论文将反应底物中的苯基换成吡啶基之后，在同样的实验条件下，反应可以比较顺利的进行。

In this thesis, a novel polymerizable cation amphiphilic compound, 4-2-(acryloyloxy ethoxy benzyl tri-ethyl ammonium bromide, was synthesized.

本论文合成了一种新型可聚合两亲化合物4-2-(丙烯酰氧基乙氧基苯亚甲基三乙基溴化铵。

A novel polymerizable amphiphilic compound with self-assembly ability, 4-2-(acryloyloxy ethoxy benzyl tri-ethyl ammonium bromide, was designed and synthesized. It exhibits good water solubility, strong self-association ability and response to extra-stimulation.

设计并合成了一种新型具有自组装功能的可聚合两亲化合物4-2-(丙烯酰氧基乙氧基苯亚甲基三乙基溴化铵，它易溶于水，具有很强的自缔合能力和对外界刺激的响应性。

Now, however, all children continue in "comprehensive" schools, and the eleven-plus determines which courses of study the child will follow.

然而现在，所有的孩子都要在综合学校继续学习，所以这次考试只是决定他们将要学习哪些课程。

Cultivatable land , and led to a general recognition that development must not be carried at the cost of agriculture .

城区的迅速扩大在很多情况下侵占了宝贵的可耕地，使人们普遍认识到发展不能以牺牲农业为代价。