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Then SAM precipitation was carried out by picric acid and SAM precipitated is higher than 90%. After butanone extraction, acetone precipitation and SAM sulfate or SAM double salt of sulfate and p-tosylate formation, the stable SAM salt was obtained.

结果表明,苦味酸是一种选择性较好的沉淀剂,沉淀步骤得率在90%以上,制备SAM的硫酸盐的总得率在60%以上,而硫酸对甲苯磺酸双盐的得率在50%以上,产物的纯度达到了95%以上,已经达到了国外同类产品的质量指标。

Objective After Intense pulsed light irradiation cavia cobaya skin, to evaluate the histological change of skin with HE stains; to evaluate the collagen fiber change with nitroxanthic acid stains; to quantitative analysis of hydroxyproline content. Confirm mechanism of action for Intense pulsed light on sun-damaged human skin.

目的 用强脉冲光照射豚鼠背部皮肤后,通过HE染色观察皮肤组织学的改变;用苦味酸染色观察皮肤胶原纤维的改变;定量分析豚鼠皮肤羟脯氨酸的含量,观察皮肤胶原蛋白的变化,进一步研究强脉冲光治疗皮肤光老化的作用机制。

A gas generator for the pre-tensioner of car-belt is studied in this paperThe main research includes: the effect of the diameter of bridgewire to thelectric sensitivity, the electric sensitivity of Pb2and C6H3O7N6Kigniting compositions, the design of the squib charge and the design of thgas generant.

论文摘要本课题研究了汽车安全带预紧器用气体发生器,主要研究内容有:桥丝直径对点火头电感度的影响;硫氰酸铅[Pb2]和苦味酸钾[C6H2O7N3K]两类点火药的电感度;点火具的装药设计;气体发生剂的设计等。

The periostea of both experimental and control side of the mandibular ramus were taken and prepared, 2 of each 5 rabbits in a group were prepared for HE stain detection and 3 for proliferating cell nuclear antigen immunohistochemical detection.Results:1, The newly formed bone was detected on the lateral aspect of mandibular ramus after periosteal distraction. The bone was shaped like a hill. It looked very low and was full of holes at postoperative day 28. With the time of consolidation period lengthened, the newly formed bone matured gradually. X-ray examination showed the new bone shaped like a hill. The average values of new bone height at postoperative days 28,35,42 and 56 were 1.86 + 0.15mm, 2.29 + 0.29mm,3.19 + 0.13mm and 4.70 + 0.45mm. Histological examination of both HE stain and picricacid-fuchsin stain showed the increase in the number of osteoblasts and the change in the orientation of collagen fibers and bone trabecula. There were no significant differences between newly formed bone and original bone on the lateral aspect of mandibular ramus at postoperative day 56 histologically.2 Compared with the control side, the distracted periostea proliferated obviously under the microscope, and the number of periostealcells increased with satiation of cellular nuclear per unit area. The images of PCNA immunohistochemical stain of periosteum showed that the experimental periosteum proliferated obviously after distraction compared with the control side.

结果:骨膜牵张成骨的实验研究南京医科大学硕{学位论文l、骨膜牵张后,可见下领升支外侧的骨皮质上有新骨形成,新骨呈山峰状凸起,术后第28天的新生骨较低平,多孔隙,随着固定时间的延长,新骨逐渐成熟;下领升支前后向切线位X线投照显示新骨呈山峰样隆起;经测量,术后第28、35、42和56天组平均新生骨厚度分别为x.86士0.15mm、2.29士0.29mm、3.19士0.13mm和4.70 土0.45mm;脱钙骨组织的HE染色和不脱钙骨组织的苦味酸一品红染色的组织学观察均显示了新生骨在成骨细胞数量上的增长,以及胶原纤维和骨小梁排列方向上的变化,术后第56天的新生骨在组织学上与原升支骨组织已无明显区别。2、HE染色显示,与对照组相比较,实验侧骨膜增生明显,细胞间排列紧密,单位面积内骨膜细胞数增多,细胞核饱满;骨膜PCNA 免疫组化染色显示,与对照侧相比较,实验侧骨膜在牵张后出现了明显的增生迹象,PCNA阳性细胞分布紧密,单位面积内阳性细胞数较对照组多,靠近骨表面的骨膜中的阳性细胞数更多而且分布更为紧密。

Materials and methods: The lung preparation of 6 SARS death patient (died in 9,14,20,29,33,38d) and 6 macaque model (killed in 7,12,14,14, 32, 35d)were objects. Pathological changes, collagen fibers, lattice fibers, elastic fibers, collagen I and III in lungs and fine structure changes were studied by routine H.E dyeing, trigeminy dyeing, trinitrophenol- sirius red staining and polarization microscope, electron microscope and image analysis. Expression of Vimentin、 TGFβ_1、 TNF α、 IL-1β and MMP-2 were detected by immunohistochemistry.Results:1. Pathological changes of SARS death patient.

材料与方法:以6例SARS死亡患者(分别于发病后9、14、20、29、33、38d死亡)和6只猕猴实验模型(分别于染毒后7、12、14、14、32、35d活杀取材)肺标本为对象,应用H.E染色、三联染色、苦味酸-天狼猩红-偏振光法、电镜和图像分析等技术,对比性观察SARS肺组织病理变化和纤维化的病理过程、胶原纤维、网状纤维和弹力纤维的变化特点、Ⅰ型与Ⅲ型胶原纤维的数量和分布规律,旨在探讨SARS肺纤维化的病变经历过程及特点;利用免疫组织化学和形态计量学技术检测SARS死亡患者肺脏的Vimentin、TGFβ_1、TNFα、IL-1β和MMP-2等与炎症反应和纤维化相关活性因子,探讨其发病机制。

X 6.36(3)? is formed.Liquid-liquid extraction experiments, between twelve heterocyclic thioalkoxycalix[4]arene on the lower rim, fifteen heterocyclic thioacetamidecalix[4]arene on the upper rim and Na~+、K~+、Cs~+、Mg~(2+)、Cu~(2+)、Co~(2+)、Cd~(2+)、Ni~(2+)、Pb~(2+)、Hg~(2+) and Ag~+ picrates, have been carried out and their results are compared.

分别将十二个下沿含有杂环硫烷氧基杯芳烃衍生物和十五个上沿含有杂环硫乙酰胺基的杯芳烃衍生物与Na~+、K~+、Cs~+、Mg~(2+)、Cu~(2+)、Co~(2+)、Cd~(2+)、Ni~(2+)、Pb~(2+)、Hg~(2+)和Ag~+的十一种苦味酸盐进行了离子萃取实验,并对两类衍生物与不用金属离子的萃取能力进行了分析和比较。

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。

Its advantage is that it can be used in smaller units.

其优点在于可以在较小的单位中应用。