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Between the ganglion cell layer and the rods and cones there are two layers of

在神经节细胞层与视柱细胞和视锥细胞之间有两层

Purpose To investigate the role of Muller glia in retinal progenitor cells differentiation into retinal ganglion cells.

目的 研究Muller细胞在视网膜前体细胞向视网膜神经节细胞分化中的作用。

Results1.In diabetic rats,the pathological change of the retinal structure displayed the decrease of the retinal ganglion cells\' number,and the signs of the apoptosis in different degrees could be found in the altrastructure of retinal neurons,including:cell shrinkage,chromatin margination and nuclear collapse,and so on.

结果1。随糖尿病大鼠病程延长,逐渐出现视网膜神经节细胞数量减少、细胞排列紊乱的病理改变,透射电镜下可见视网膜神经细胞出现胞浆浓缩、细胞体积缩小、染色质边聚、细胞核固缩、断裂等不同阶段的凋亡征象。

Results:It was found that in experimental group,retinal neurofibril were disorder,the ganglion cell,the cells in inner and outer nuclear layer presented nibble like lysis,necrosis and lose.gradually at 1,3,5 day after moc...

结果:接种后1、3、5天,对照组未见异常改变,绿脓杆菌接种组视网膜神经纤维排列紊乱、消失,神经节细胞、内核层细胞及外核层细胞从内向外呈蚕蚀样溶解或坏死脱落。

The results showed that in light adaptation, zinc was preponderantly present in the outer plexiform layer.

结果发现:明适应条件下,外网层、部分光感受器、双极细胞、无长突细胞以及神经节细胞胞体锌离子着色明显。

Different doses (25,50 and 100 mg/L)of gentamicin were add to the medium of SGC,and cultured for 14 days.After that,the specimen was fixed with 4%paraformaldehyde and stained with toluidine blue.

为观察硫酸庆大霉素对培养的小鼠耳蜗螺旋神经节细胞的细胞生存数和细胞突起长度的影响,在单离培养的出生1-5 d的NIH小鼠SGC培养液中,加入不同浓度的硫酸庆大霉素(25,50,100 mg/L)。

The retina in Andrias davidianus were observed with light and scanning electron microscope.

用光镜和扫描电镜观察了大鲵视网膜各类细胞的形态及分布,对视细胞和节细胞进行计数。

Of 92 acutely dissociated dorsal root ganglion cells recorded by current patch-clamp technique, 34% were discharged by FA application with the mean onset latencies of the first action potential being (367.34+/-32.96) s. All the FA-sensitive cells were identified as nociceptor cells by their distinguishable features of AP including longer duration, existence of a hump on the repolarizing phase, and longer after-hyperpolarization of APs.

运用电流钳记录的92个背根神经节细胞中,大约有34%的中、小细胞对甲醛溶液敏感,产生动作电位的发放,其产生动作电位的潜伏期是(367.34±32.96) s,并且单个动作电位复极化相具有伤害性感受器细胞的特征性,如动作电位间期较长、复极化相有&驼峰&以及较长的后超极化相。

In electron microscopy endothelial cell of capillary and mitochondrial was edematous obviously, the basement membranes were thickened. RGCs were vacuolated, chromatin of nucleus aggregated marginally decreased and densification. Some of RGCs were necrosis, nucleus were dissolved, mitochondria was edematous, the rough endoplasmic reticula decreased obviously.

电镜下视网膜毛细血管内皮细胞明显肿胀,胞体变圆,突向管腔,线粒体肿胀,空泡化,基底膜增厚,视网膜神经节细胞胞体变形,核明显固缩,核膜消失,胞浆空泡化,线粒体肿胀,细胞表面突起减少,多聚核糖体及粗面内质网显著减少。

Results The supratentorial lesions involved the occipital lobe in 4, frontal lobe in 3, fronto-occipital lobe in 2, temporo-occipital lobe in 3, lateral ventricle in 1 case and the saddle region in 1. All the lesions were large in volume and most of them presented heterogeneous signals in MRI. Of the 14 cases, 12 showed cystic degeneration and necrosis, 2 had hemorrhage and 6 showed signs of emptied small blood vessels. Twelve cases had heterogeneous enhancement and 2 had moderate enhancement. Pathologically, 10 cases of neuroblastomas were identified, along with 3 ganglioneuroblastomas and 1 atypical rhabdoid tumor.

结果 病灶位于顶叶4例,额叶3例,枕顶叶2例,颞枕叶3例,侧脑室1例,鞍区1例,病灶普遍较大,病灶绝大多数信号不均匀,病灶内可见囊变/坏死(12例)、出血(2例)、流空小血管影(6例),增强后病灶呈明显不均匀强化(12例),中等强化2例;神经母细胞瘤10例,节细胞神经母细胞瘤3例,非典型横纹肌样瘤1例。

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