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There were actually SP,CGRP and VIP in three predominant superfical ganglial plexus of the guinea pig heart and the three peptides could possibly modify the activities of myocardiocytes and vessels of heart directly.

豚鼠心脏表面主要神经节丛内确实存在SP、CGRP及VIP,并且这3种神经肽可能直接参与心肌细胞和心脏血管活动的调控。

Using immunofluorescence double label method to observe GAP-43 expression of jugular ganglionic SP positive cell after the onset of asthma.

四、应用免疫荧光双标技术,在哮喘模型上观察了哮喘发作后,颈静脉节SP免疫阳性细胞GAP-43的表达变化。

BrdU labeling indicated that the positive cells in the lateral ganglionic eminence migrated in a similar way to those in control group 6 h following Xray irradiation, the positive cells were observed to be around the cystic cavities in cortexstriatum 2 days later and migrated to the ventral cortical plate 4 days later.

BrdU标识显示腹侧端脑的外侧节隆起的神经细胞移动类似于正常对照组,2 d后阳性细胞分布在皮质纹状体区形成的空洞周围,4 d后移动到腹侧皮质板。

This evidence suggests that, myf5 is involved in axial and non-axial mesoderm interaction during gastrulation. The disrupted hindbrain segmentation affects the fgf3 signaling, thus causing the CNC to undergo apoptosis.

这些证据显示,myf5在原肠化过程扮演重要角色,Myf5的缺失造成后脑fgf3讯息传递缺失,干扰后脑分节发育,进而影响之后的神经嵴细胞与软骨的发育。

Transgene-deried met-enkephalin accumulated in numerous nere cell bodies of trigeminal ganglion and was transported through the sensory nere fibers located in the infraorbital nere.

转基因衍生的蛋氨酸脑啡肽聚集在多数三叉神经节神经元细胞体中,并通过眶下神经感觉神经纤维进行输送。

Furthermore, cells in different living stages responded to the treatments (Oryzalin and Ca〓) differently, young active internodal cells seemed to be more sensitive.

并且不同生长状况的节间细胞内的微管骨架,对Ca〓和Oryzalin处理敏感性表现也各不相同。

Distribution and coordination environment of lanthanum in internodal cells of Chara have been determined by inductively coupled plasma-mass spectrometry and X-ray absorption spectroscopy.

利用电感耦合等离子体质谱和X射线吸收谱研究了稀土元素镧在轮藻节间细胞中的分布和配位环境。

The results are: 1 the stricture of the capillaries of stria vascularis was observed in most cochleae of rickety rats and, segmental deletions of the outer hair cells on the first turn of cochlea were found in a small number of rickety rats; 2 the perilymphatic ionized calcium concentration significantly re- duced and the threshold of CAP (Compound Action Poten- tials of the eighth nerve) significantly rose in rickety rats in comparison with those of normal control; 3 gentamicin results in an increase of the perilymphatic ionized calcium concentra- tion in rickety rats; 4 the cochleae of the rickety rats appeared to be less vulnerable to the ototoxicity of gentamicin than the normal one.

研究包括两个方面,其一是&佝偻病的感觉神经性耳聋及其对庆大霉素耳毒性作用的耐受性&,系用大白鼠建立维生素D缺乏性佝偻病动物模型,发现:(1)佝偻病大白鼠耳蜗血管纹毛细血管狭窄,少数动物耳蜗底回外毛细胞有节段性缺失;(2)佝偻病大白鼠的耳蜗鼓阶外淋巴钙离子浓度降低,CAP(听神经复合动作电位,以下简称CAP)听阈提高;(3)庆大霉素可使佝偻病大白鼠耳蜗外淋巴钙离子浓度上升;(4)佝偻病大白鼠耳蜗在功能和形态上都比正常者更能耐受庆大霉素的耳毒性损害。

To study furderly the activity of CNTF mutant designed by computer molecular modling,this study used the methods of dissociated cultures of chick dorsal root ganglion、TF-1 prolification and the normal mice′weight loss tests.

为了进一步研究我室应用计算机分子模拟设计并表达纯化的睫状神经营养因子突变体蛋白的生物学活性,分别采用鸡胚背根神经节无血清培养法、TF-1细胞增殖法、正常小鼠减重法对其活性进行研究。

The results indicated that the mutant protein promoted the survival of dorsal root ganglion、induced TF-1 prolification and made the normal mice lose weight,decrease appetite and reduce fat index.The weight loss effect was dependant with its administration dosage,ED50 was 150.986?

结果是突变体蛋白能促进鸡胚背根神经节的生长;促进TF-1细胞增殖,MTT测定法表明突变体蛋白与国际参考品相比,比活不低于2.0×106U/mg;使正常小鼠的体重减轻,摄食量减少,脂肪指数下降,并且体重的减轻与突变体蛋白的给药剂量呈现良好的剂量依赖关系,其ED50为:150.986?

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