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Previous studies have revealed that aganglionic or morphological and numerical abnormalities of the intestinal intramural ganglia may contribute to the pathogenesis of the intestine motility obstacle of them.

目前认为HD和HAD肠动力障碍的发病机制主要是病变肠段粘膜下神经丛和肌间神经丛的神经节细胞的缺失和减少,病变肠壁内的副交感、交感及第三类神经系统均有改变。

The abnormal distribution of NGFR in the aganglionic bowel suggests involvement of NGFR in the pathogenesis of HD. NGFR immuno-staining may be a valuable diagnostic tool in HD.

NGFR在无神经节细胞肠段的异常分布可能与HD的发病机理有关,NGFR免疫组化染色对HD可能具有诊断价值。

NGFR positive nerve fibres were markedly reduced or absent in muscular layer and submucous layer while the hypertrophic nerve trunks in myenteric and submucosal plexuses showed a sheath of intense staining in the aganglionic colon from patients with HD.

结果 丰富的NGFR染色阳性神经纤维分布于正常结肠环肌层及粘膜下层,少量分布于纵肌层,NGFR染色阳性神经元分布于肌间神经丛及粘膜下神经丛;NGFR 染色阳性神经纤维在HD无肌间神经节细胞肠段肌层及粘膜下层内明显减少或缺如,而肌间肥大的神经干及粘膜下神经干为NGFR染色阳性,并且在其外周可见一强阳性染色带。

In this study we attempted to correlate results of behavioral studies with responses of electrophysiological recorded DSGCs.

在本实验中我们用电生理记录和行为观察相结合的方法来探讨视网膜方向选择性神经节细胞的输出反应和OKN的相关性。

The epineurial vessels run along the nerves length and gave off branches, distributing along nerve bundle, to enter into endoneurium. The endoneurium contained only capillaries. Arteriolovenular anastomoses were few in trigeminal nerve root. The distribution of microvessels in trigeminal nerve root was uneven. The number of microvessels in the medial portion was less than that of the distant.

神经外膜血管沿神经根径向走行,沿途再发侧支斜行或横行入神经束之间,顺神经根束分布,并发侧支进入神经内膜;半月结内微血管围绕神经节细胞分布;三叉神经根内的微血管配布不均,其近侧端微血管数量较少,远侧端微血管数量较多。

This indicated that all of FGN set in excitatory inputs to IMG neu...

定量研究表明后者比前者对神经节细胞兴奋的影响更大。

Then the number of survival retinal ganglial cells and the expression of Nogo-A in optic nerve and retina after injured were observed.

目的:观察地塞米松对家兔视神经钳夹伤后视网膜神经节细胞存活的影响及损伤视神经、视网膜Nogo-A表达的变化。

After the optic nerve injury, dexamethasone can increase the number of survival retinal ganglial cells and down-regulate the expression of Nogo gene.

视神经损伤后,地塞米松能够增加视网膜神经节细胞的存活数量,并下调Nogo基因的表达,这可能是地塞米松的药理作用机制之一。

BACKGROUND: Studies have demonstrated that ultrasound-mediated microbubble destruction significantly improves transfection efficiency of enhanced green fluorescent protein in in vitro cultured retinal ganglial cells.

背景:已有报道,超声微泡能明显提高体外培养的增强型绿色荧光蛋白基因转染视网膜神经节细胞的效率。

AIM: To observe the effect of sodium glutamate by different administration time on the injury degree of retinal ganglial cells in juvenile guinea pig, and establish an ideal retinal excitotoxicity model.

目的:观察谷氨酸钠不同给药时程对幼年豚鼠视网膜神经节细胞损伤的程度,以建立简便而稳定可靠的视网膜兴奋毒性损伤模型。

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