舒张

Inhibition of 〓 exchange decreases the systolic and diastolic function of perfused hearts, whereas stimulating 〓 exchange improves the cardiac function, indicating that potentiating 〓 exchange may be a new pathway to improve the pump function of heart.

抑制〓交换可降低正常大鼠心脏的收缩和舒张功能，激动〓交换可增强正常大鼠心脏的收缩和舒张功能，提示增强〓交换可能是提高心泵功能的一个新途径。

Fig. 3.Effect of endothelial cells on relaxation to ONOO- in precontracted rabbit pulmonary arterial rings by 10－6 mol/L PE in vitro.

与内皮完整的 PARs相比，预收缩的去内皮PARs对ONOO-的舒张反应明显增强，舒张反应曲线明显左移。

Acclimatization 1.73±1.82** 0.61±0.06 0.98** P＜0.01 vs normoxic rats.After the aorta preparations were precontracted with NE at the concentration of 0.62 μmol/L, a ccumulative vasodilative effects of ACh were tested.

与常氧对照组相比，急性低氧和间断低氧习服后，大鼠主动脉对ACh各浓度(10- 9～10-5 mol/L)引起的舒张反应显著减弱(P＜0.01)，其最大舒张分别为常氧对照组的87.3％和79.7％，其EC50值分别为1.34和1.73 μmol/L，分别为常氧对照组EC50值0.20 μmol/L的6.7和8.6倍(表2)。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

Ginger extract and4-Retro-decoction can improve the cardiac systolic/diastolic function and reduce peripheral resistance,with ginger extract showing a strong effect.Ginger extraction showed a better performance in reducing terminal diastolic pressure,which is beneficial to lower the before-load of heart.Consequently,coronary perfusion can be improved.

干姜提取物和四逆汤均具有增强心肌收缩和舒张性能、降低外周阻力作用，以干姜提取物的作用更强；同时干姜提取物在降低舒张末期压方面具有优势，更有利于减轻心脏前负荷，改善冠脉灌流。

Ginger extract and4-Retro-decoction can improve the cardiac systolic/diastolic function and reduce peripheral resistance,with ginger extract showing a strong effect.Ginger extraction showed a better performance in reducing terminal diastolic pressure,which is beneficial to lower the before-load of heart.Consequently,coronary perfusion can be improved.

干姜提取物和四逆汤均具有增强心肌收缩和舒张性能、降低外周阻力作用，以干姜提取物的作用强；同时干姜提取物在降低舒张末期压方面具有优势，更有利于减轻心脏前负荷，改善冠脉灌流。

Objective To assess the changes of local and global left ventricular systolic long axis function in patients with diastolic heart failure by strain rate imaging and compare with isolated left ventricular diastolic dysfunction and left ventricular systolic heart failure to discuss its clinical value.

目的 应用应变率显像技术检测舒张性心力衰竭患者左心室局部及整体心肌长轴收缩功能的变化，并与单纯性左心室舒张功能障碍和收缩性心力衰竭患者进行比较，进一步探讨其临床意义。

Measurirg indxes included:(1) Electrocardiograh;(2) Hemodynamics: cardiac output, pump output, aortic pressire, pulmo nary artery pressure, left atrium pressure, right atrium pressure, left ventricular end systolic pressure, left ventricular end diastolic pressure, LV-dp/dt, right ventricul ar end systolic pressure, RV-dp/dt, systolic pressure time index, diastolic pressure time index, endocardial viability ratio;(3) Myocardial metabolism: coronory sinus blood flow, myocardial oxygen consumption, myocardial lactate extractiorn;(4) Ischemic myocardial area;(5) Ultrastructure of myocardium.

测量指标包括：①心电图；②血流动力学：心输出量、泵输出量、主动脉压、肺动脉压、左房压、右房压、左室收缩末压、左室舒张末压、左室压的一阶导数、右室收缩末压、右室压的一阶导数、收缩压力时间指标、舒张压力时间指标、心内膜下心肌供血比率；③心肌代谢；冠状窦血流量、心肌氧耗量、心肌乳酸摄取量；④心肌缺血面积检查及缺血心肌的超微结构观察。

The height, weight, blood pressure, fasting plasms glucose, fasting serum insulin, glycosylated hemoglobin (HbA1c), triglyceride, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, and serum nitric oxide were measured before and after the therapy. The body mass index and homeostasis model assessment-insulin resistant index were calculated. The flow-mediated dilatation and endothelium independent dilatation were measured by high-resolution ultrasound.

治疗前后均检测身高、体质量、血压、空腹血糖、血浆胰岛素、糖化血红蛋白(HbA1c)、甘油三脂、胆固醇、低密度脂蛋白、高密度脂蛋白数(homeostasis model assessment-insulin resistant index， HOMA-IR)，并用高分辨超声技术检测肱动脉血流介导的内皮依赖性舒张(flow-mediated dilatation， FMD)和硝酸甘油介导的非内皮依赖性舒张(endothelium independent dilatation， EID)。

Then the responses of artery to phenylephrine acetylcholine, sodium nitroprusside and norepinephrine were studied.

结果：转基因血管内皮细胞的增殖较对照组活跃，动脉的内皮依赖性舒张反应较强，10 －6mol／L 的乙酰胆碱引起的舒张为33－08％±10－01％，对照组为－ 17－57％±5－59％，P＜ 0－01 。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐