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Adrenoceptor antagonization did not change the tension of femoral artery, but abolished the ISO induced vasorelaxation of coronary artery.

1受体阻断不影响ISO产生的股动脉血管舒张,但消除了冠状动脉的血管舒张

There are some errors in measuring blood pressure by sphygmomanometer method. Apparent error is found in systolic pressure in patients with hypertension, but not in diastolic pressure.

用汞柱式血压计测量肱动脉血压的值与实际值有一定差异,对于高血压病人,收缩压误差较大,而舒张压则较准确;对于正常人收缩压易低估,舒张压易高估。

Methods:After 1-week washout and 2-week placebo run-in period,patients with seated diastolic blood pressure 95-115 mmHg (n=76) were administrated with losartan 50 mg once-daily or losartan 50 mg/hydrochlorothiazide 12.5 mg once daily for 4 weeks,followed by double doses once daily for another 4 weeks in those patients with SeDBP≥90 mmHg.

坐位舒张压95~115 mmHg(1 mmHg=0.133 kPa)的76例原发性高血压患者,经1周药物洗脱期,2周安慰剂期后,随机服用氯沙坦50 mg(氯沙坦组,n=37),每日1次或氯沙坦50 mg与双氢克尿噻12.5 mg合剂(氯沙坦+双氢克尿噻合剂组,n=39),每日1次。4周末坐位舒张压≥90 mmHg者,剂量分别加倍,继续服用4周。

There was no statistically significant difference in parameters of IVS motion between obstructive and nonobstructive HCM.The data of hypertrophic LVPW motion were lower than those of normal subjects,as well as those of nonhypertrophic LVPW in HCM group.

左室后壁肥厚者收缩期及舒张早期的DTI测值多低于正常,而左室后壁不肥厚者收缩期指标无明显变化,舒张早期指标低于正常;两者相比,前者收缩期及舒张早期各参数多低于后者。

Methods 20 healthy volunteers and 37 patients with CAD were involved in this study. Color changes resulted from CK timing and amplitude were observed at parasternal short-axis view, apical four-chamber view and two-chamber view; The percent of regional fractional area change in 30﹪ diastolic period , namely color kinesis diastolic index, were obtained using ICK software.

观察20例正常人和37例冠心病患者胸骨旁左室乳头肌短轴观、心尖四腔、两腔观各节段心肌舒张期心内膜位移引起彩阶的变化,并运用ICK定量分析软件计算出心内膜于舒张早期30﹪时间内位移的面积占整个舒张期内膜位移面积的百分比,即心内膜位移指数。

All patients underwent echocardiography and conventional 12-lead electrocardiogram examination,Parasternal short axis at papillary muscle level of left ventricular cross-section,Application of M-mode ultrasonography were measured end-diastolic ventricular septal diameter,End-diastolic left ventricular posterior wall diameter,The largest left ventricular end diastolic diameter and left ventricular end systolic diameter.

所有患者均行超声心动图和常规12导联心电图检查,在胸骨旁左室短轴乳头肌水平切面,应用M型超声分别测量室间隔舒张末期厚度、左室后壁舒张末期厚度、左室最大舒张末期内径和左室收缩末期内径。

All subjects recieved the test of Two-Dimensional echocardiography and PW-TDI.3.1 LV end-diastolic diameters, RV end-diastolic diameters and inter-ventricular septum and posterior wall thicknesses were measured from the parasternal long-axis projection. LV end-systolic and diastolic volumes,RV end-systolic and diastolic volumes were obtained from the

所有入选者均行常规二维超声和组织多普勒超声心动图检查 3.1 常规二维超声心动图(two-dimensional echocardiography,2D)检查:采用胸骨旁左室长轴切面M型测量左室舒张末期前后径、右室舒张末期前后径、室间隔厚度、左室后壁厚度;心尖四腔、二腔切面面积勾画法分别测量左室、右室舒张末期容量和收缩末期容量并计算左室

There was a good correlation between Ptw,AVCtw,MVOtw,PTV,PUV,UntwR and age.2.Assessment of left ventricular twisting and untwisting of DCM patients19 DCM patients(range 18-80 yr,mean age 50.52±17.52 yr,2 females) and 21 age- and sex-matched normal controls(range18-80 yr,mean age 49.05±16.94 yr,5 females) were enrolled into this study.Then DCM patients were divided into two groups:E/A<2 group and E/A>2 group.The routine echo showed the left ventricle dilated and EF decreased.The results show that LV rotation degree, rotation velocity at baseline and apex were irregular changeable with the cardiac cycle;the rotation direction was clockwise at the base and counterclockwise at the apex,and are combined to yield a systolic counterclockwise twisting as seen from the apex,but the rotation at the basal and apex were the same direction in some patients.

扩心病患者左室扭转及解旋特征的研究选择扩张型心肌病(Dilated Cardiomyopathy,DCM)组患者19例(男性17例,女性2例,年龄18~82岁,平均50.52±17.52岁),健康体检者21例(男性16例,女性5例,年龄18~80岁,平均49.05±16.94岁)作为对照组,扩心病患者按照E/A分为E/A<2、E/A>2两个亚组,结果显示:常规超声显示DCM组LVDd值增大,EF值减小;DCM患者左室心底部与心尖部心肌旋转角度、旋转速度随心动周期变化曲线明显紊乱;与正常组比较,DCM患者左室整体扭转角度和速度分别为(6.49±1.82)°、(67.84±15.60)°/s,较正常人显著减低P<0.01左室舒张末及收缩末扭转角度DCM患者较正常人显著减低(P<0.01,左室舒张末及收缩末时间在DCM-E/A>2组较正常人及DCM-E/A<2组显著缩短P<0.01DCM患者左室解旋速度较正常人亦显著减低(P<0.01,左室功能轻中度减低(DCM-E/A<2)患者解旋率[(0.29±0.07)%]较正常人[(0.42±0.11)%]明显减低,但当左室功能重度减低(DCM-E/A>2)时左室解旋率[(0.63±0.35)%]较正常人反而增加;左室整体扭转角度、舒张末扭转角度、收缩末扭转角度、解旋与左室射血分数未见明显相关性。3。

ONOO〓 had direct vasoactive effect for relaxation of precontracted isolated pulmonary artery. Relaxing action of ONOO〓 was weak and was negtively regulated by endothelial cells, further supporting the notion that ONOO〓 may be involved in pulmonary hypertension in the early stage of ES.

用离体血管环检测张力方法,发现ONOO〓具有一定的舒张肺动脉作用,但舒张效应较弱,并受到血管内皮细胞的抑制性调节;抑制K〓通道和PARS活性可增强ONOO〓对离体兔肺动脉的舒张作用。

Conclusions(1) Because of different types and magnitudes of LVH, LV function was significant impaired and LV motion asynchrony in systole and diastole existed in HCM patients; Impairment of LV function and synchrony existed only in diastole in HHD patients.

结论1。由于左室肥厚的发病机制、类型及程度不同,HCM患者存在严重左室心肌收缩、舒张功能下降,且左室运动于收缩期、舒张期均存在明显协调障碍;HHD仅于舒张期出现左室心肌功能下降及运动的不协调性。2。

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