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Combined with animal model of peradaptation to myocardium ischemia , the research observed the level of enzymatic dynamics of myocardium, SOD,MDA,ET and correlation peptide of calcitonin gene in peripheral blood and cardiac function, apoptic cell and expression of apoptosis regulatory gene, ultrastructure of myocardium with BIOPAC16, in situ end labeling and hybridism, optic microscope and electron microscope. The study of animal model of peradaptation to myocardium ischemia illustrated that the peradaptation and pretreatment with Wenxin capsule could be positively protective for the injury of ischemia reperfusion. The protection is mainly reflected by reduction of infarction area, correction of heart rhythm abnormality of ischemia reperfusion, melioration of the contraction and relaxation function of myocardium, recovery of the subcellular structure and themelioration of the abnormality of biochemical and bioactive substance in the myocardium.

并结合心肌缺血预适应动物模型,采用BIOPAC16导生理记录和分析处理系统处理心肌功能指标,采用原位末端标记及原位杂交技术标记凋亡细胞及凋亡相关调控基因的表达,采用光电镜技术观察心肌超微结构的变化,同时观察外周血心肌酶、超氧化物歧化酶、丙二醛、内皮素、降钙素基因相关肽等水平,结果表明心肌缺血预适应及温心胶囊预处理对心肌缺血再灌注损伤具有肯定的保护作用,其保护心脏作用主要表现在缩小心肌梗死范围、抗缺血再灌注心律失常、改善心肌收缩和舒张功能、减轻心肌超微结构损伤,调节心肌生化物质及生物活性物质的生成和释放。

Objective To investigate the effect of cholesterol-lowering therapy with simvastatin on endothelium-dependent relaxing function in patients with hypercholesterolemia.

目的 研究辛伐他汀对原发性高胆固醇血症患者血管内皮依赖性舒张功能的影响。

Studies were included in our analyses if they were population-based cohort or postcardiac surgery cohort and investigated the incidence of AF in relation to the body mass index categories.

背景:肥胖与左心房扩大和心室舒张功能障碍有关,后两者均为心房纤颤的危险因素,然而肥胖是否为心房纤颤的危险因素尚不明确。

BNP makes an useful indicator for LV diastolic function, It also is helpful to diagnosis of cardiac dysfunction.

血清BNP水平升高可反映左室舒张功能障碍及其严重程度,对心功能不全的早期诊断具有重要临床价值。

The human heart is the center of the cardiovascular system. Integrated with mechanical, electrical, neural and biochemical properties, the heart is difficult to model, and there is no ideal integral model now. The developed electrical models haven't considered the mechanical properties and blood flow process in the heart; while the mechanical ones have normally deal with the heart in the diastole period, and the electrical activity was simplified too much although some mechanical models have investigated the heart during systole.

心脏是循环系统的核心,它集机、电、神经和生化控制于一体,建模难度很大,目前尚无较理想的统一模型;心脏电生理模型未与心脏的机械动力过程和血液流动过程联系起来;而心脏力学模型大都只研究舒张期的力学特性,即使研究收缩期心脏的力学问题,也往往对心电兴奋做了许多简化假设。

At catheterization, all patients had elevated intrapericardial pressure (median, 12 mm Hg; interquartile range, 7 to 18) and elevated right atrial and end-diastolic right and left ventricular pressures.

在进行导管插管时,所有病人的心包内压都升高(中位数为 12mmHg,四分位数间距为 7~18mmHg),右房压以及左室和右室舒张期末压也都升高。

To observe influence of respiration on hemodynamics and interventricular septal motion in patients with pericardial effusion with echocardiography and to provide theoretical basis for its clinical application.

根据新假说,探讨临床无创测定肺动脉压和左室舒张末压新方法,为呼吸影响心功能机制新假说的实际临床应用打下基础。

Objective:To observe the change of intima|media thickness of carotid artery and endothelium|dependent vasodilatation function of brachial artery in aged patients with hypertension.

目的:观察老年高血压对颈动脉内膜中层厚度及血管内皮依赖性舒张功能的影响及其临床意义。

Fig. 3.Effects of HS-142-1, TEA and MB on the relaxation of human intramammary artery induced by VNP.

HS-142-1 (20 μ mol/L)可以使VNP舒张HIMA的作用几乎完全消失(图3)。

Ren Shen Jian Xin Capsule has favorable clinical curative effect on coronary atherosclerotic heart disease left ventricular diastolic dysfunction and could improve the living quality of the patients. It can reinforce qi and activate blood, alleviate pain by promote circulation, invigorant heart and recover health.

人参健心胶囊具有益气活血,温阳通络,养心复元的作用,对老年人冠心病左室舒张功能不全具有良好疗效,可明显提高患者生活质量。

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