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How to evaluate diastolic function accurately is still pending.

如何准确评价舒张功能仍是临床面临的主要问题。

A great quantity of clinical trials indicate that β-receptor blocker can improve the prognosis of patients and improve the dilatability and contractile function of left ventricle. Besides, it also can improve the hemodynamics, upgrade the exercise tolerance and life quality and extend the live time of the patients.

大量临床试验表明,β-受体阻滞剂不仅能改善患者预后,而且能明显改善左室的舒张和收缩功能,全面改善患者的血流动力学,提高患者的运动耐量和生活质量,延长生存时间。

So there are two ways to attack the vascular smooth muscles in terms vascular dilatation.

因此,就血管舒张而言,有两种途径来攻击血管平滑肌。

To study the effects of weight reduction on endothelium-dependent dilatation and insulin resistance in obese subjects and to explore the relationship between endothelial dysfunction and IR.

目的 观察减重对肥胖者血管内皮功能及胰岛素抵抗的影响,探讨内皮依赖性舒张功能障碍与IR的因果关系。

Objective To investigate the effect of atorvastatin on endothelial dilated function in the patients with coronary heart disease.

目的 超声检测内皮依赖性及非依赖性舒张功能,研究冠心病患者内皮功能的变化及其临床意义。

Reduced flow-mediated dilation, as measured in this study, is an early indicator of cardiovascular disease.

减少流量介导的舒张,作为衡量在这项研究中,是一个早期指标心血管疾病。

Objective: To investigate the clinical significance of the carotid arterosclerosis and endotheliumdependent dilation in coronary heart disease.

目的:研究冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床意义。

Methods 104 patients with severe heart failure were divided into two groups. The control group was treated with routine treatment (digitalis,diuretic and distend the blood-vessel) combined with Imidapril (group A,n=52). The treatment group was treated with routine treatment (digitalis,diuretic and distend the blood-vessel) combined with Bisoprolol and Midapril (group B,n=52). The course of treatment was 12 to 16 weeks. Before and after treatment,the changes of heart function,LVEF,LVESD,heart rate and blood pressure were observed.

对104例重度心力衰竭患者随机分成两组:对照组52例,予以常规用药及咪达普利等药物治疗;治疗组52例,在常规用药基础上加用比索洛尔治疗,疗程12~16周,观察治疗前后心功能、左室射血分数、左室舒张末内径、左室收缩末内径、心率、血压等指标的变化。

The change of large arterial distensibility had close relationship with SBP level,age and left ventricular diastolic function.

收缩压水平、年龄、左室舒张功能状态是与大动脉扩张性关系最为密切的因素

All the patients were followed up for months and measured respectively the changes of heart rate, blood puessure and cardiac function by the colur dopper ece.results48 patients completed the treatment.the lvedd, lvesd, heart function and symptoms were improved in both groups while the treatment group was more obvious than the control group(p<0.05).the result of hr and bp decreased significantly after treatemt comparatively(p<0.05), while the hr in the treatment decreased more obvious than the control group (p<0.01),but there was no significant difference in hr(p>0.05).conclusionon the basis of routine therapy metoyrolol and shengmaimai capsule can improve the symptoms and heart function significantly in patients with crf and chf.

随访6个月,分别测量治疗前后心率、血压,采用彩色超声心动图测量心功能进行疗效观察。结果48例患者完成研究,两组治疗后左心室舒张末径,左心室收缩末径、,心功能,症状均有改善,但治疗组比对照组明显,两组比较有显著性差异(p<0.05),两组治疗后血压心率较治疗组明显下降(p<0.01),两组患者治疗后血压无显著性差异(p>0.05)而心率有非常显著性差异(p<0.01)。

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