舒张

RESULTS Endothelium removal, NOS inhibition,β2 adrenoceptor antagonization did not change the vasorelaxation induced by ISO in coronary artery, however, abolished the vasorelaxation in femoral artery.

结果 无论冠状动脉或股动脉ISO均产生浓度依赖的血管舒张。去除内皮， NOS抑制，β2受体阻断不影响ISO产生的冠状动脉血管舒张，而完全消除了股动脉的血管舒张。

The first part consists of three experiments:(1) The rings were incubated in KH, 20, 50 mmol/L 〓 for 1 house, relaxation in response to the EDHF stimuli A23187 in 30nmol/L U46619-induced preconrtaction in the presence of 7 μ mol/L indomethacin, a cyclooxygenase inhibitor, 300μmol/L LNNA, a nitric oxide biosyhnthesis inhibitor, and 1mmol/L tetraethylammonium , a 〓 blocker, or 3 μmol/L glibenclamide , a 〓 blocker, was compared with the control;(2) After the arteries were incubated in KH, UW solution or HTK solution at 4℃ for 4 hours, endothelium-derived relaxation (percentage of 30nmol/L U46619 precontraction) was induced by A23187 in the present of 7 μmol/L indomethacir and 300μmol/L LNNA;(3) After incubation with KH, UW solution and STH (either at 37℃ in oxygenated organ chamber or at 4℃ in a refrigerator for 4 hours), endothelium-derived relaxation (percentage of 30nmol/L U46619 precontraction) was induced by A23187 in the present of 7 μ mol/L indomethacin and 300 μmol/L LNNA.

第一部分研究结果：（1）单纯浸泡于KH的冠状动脉A23187能引发66.67％的血管舒张反应，经TEA及20mmol／L、50mmol／L钾离子作用后，血管舒张反应程度显著降低，但经GBM作用后改变不明显；（2）与保存于KH的冠状动脉相比，A23187引发的血管舒张反应程度，保存于UW液的明显下降，保存于HTK液的无明显变化；（3）在37℃条件下，血管环浸泡于STH出现缓慢轻微的舒张反应，浸泡于UW液初期出现短暂收缩反应，但此后主要以舒张为主：在37℃条件下，血管经UW液保存后，U46619引发的收缩反应程度降低；不论在37℃或4℃条件下，A23187引发的血管舒张反应，经UW液保存后明显下降，但用STH保存后变化不明显。

The left ventricular internal dimension at end diastole, interventricular septal thickness at end diastole and left ventricular posterior wall thickness at end diastole were measured in the parastemal long axis view by transthoracic two-dimensional echocardiography, and to calculate left ventricular ejection fraction with Teichholtz formula and left ventricular mass with modified Devereux formula, left ventricular mass index=LVM/body surface area. From the apical four chamber and two chamber view, the basical segment and middle segment of interventricular septal, left ventricular lateral wall, anterior wall and inferior wall were obtained by tissue Doppler imaging, Regional left ventricular relaxation asynchrony index was calculated.

应用二维超声心动图在胸骨旁左心室长轴观测量左心室舒张末期内径、室间隔和左心室后壁舒张末期厚度，采用Teichholtz公式计算左心室射血分数，采用Devereux校正公式计算左心室心肌质量，左心室心肌质量指数=左心室心肌质量/体表面积；在心尖四腔心和心尖两腔心切面，应用组织多普勒成像获取室间隔、左心室侧壁、前壁和下壁的基底段和中间段8个心肌节段沿左心室长轴运动的速度频谱，测算左心室局部心肌松弛不同步性指数(regional left ventricular relaxation asynchrony index， AI)；在心尖四腔心切面，应用彩色M型多普勒超声心动图测量左心室舒张早期血流传播速度。

Primary atrial tumor has obvious characteristic on RT-3DE: All the atrial tumor display the same size of stereoimages as the tumor themselves. There is a clear boundary between the stereoimage of the myxoma and the atrial wall and there exists a short pedicle connecting the atrial myxoma to the atrial wall or the interatrial septum. The body of the atrial myxoma moves to and fro through the atrium and the atrioventricular valve with the contraction and relaxation of the heart with a fixative pedicle. Atrial myxoma leads to relative atrioventricular valve incompetence during systolic phase and relative atrioventricular valve stenosis during diastolic phase, but doesn't result in pathological changes of atrioventricular valve which restore to normal after exsection of the atrial myxoma. Malignant atrial tumor closely and extensively contact with atrial wall without obvious boundary, pedicle and movement with the contraction and relaxation of the heart.

所有心房肿瘤RT-3DE均实时显示与肿瘤大小相同的立体形态图像；心房黏液瘤立体形态图像与心房壁界限明显，都通过一短蒂与房间隔或心房壁相连，瘤体以蒂为固定点随心脏收缩、舒张在心房与房室瓣口之间往返运动；心房黏液瘤收缩期瘤体导致房室瓣相对关闭不全，舒张期瘤体导致房室瓣相对狭窄，但瘤体不引起房室瓣器质性病变，瘤体摘除后房室瓣功能即恢复正常；恶性心房肺瘤立体形态图像与心房壁关系密切，界限不明显，接触范围广泛，无蒂，瘤体不随心脏收缩、舒张运动。

Level of hypertensive group HsCRP is remarkable as a result prep above contrasts group, hsCRP level and style quality exceed mark, smoking, blood fat to reach diameter of end of left room diastole to increase mussily, contractive end diameter adds left room, left ventricular diastole is inchoate mitral valve is the biggest blood stream speed and diastole are terminal mitral valve is the biggest.

结果高血压组hsCRP水平显著高于对照组，hsCRP水平和体质量超标、吸烟、血脂紊乱及左室舒张末径增加、左室收缩末径增加、左心室舒张早期二尖瓣最大血流速度和舒张晚期二尖瓣最大血流速度之比异常有关。

Methods The left ventricular diastolic function,the blood speed during quick filling phaseof left ventricular of the mitral valve orifice,the peak value of the late phase of left ventricular diastolic pariod;E/A ratio,the time for isovolumetric relaxation phase of left ventricular,the reducel time of peak E,and the distance between peak E of mitral valve and intervertricular septum of left ventricular were measured respectively.

摘要］ 目的应用彩色多普勒超声心动图测定冠心病左室舒张功能，临床提供可靠的诊断及治疗依据方法分别测定冠心病组及对照组的左室舒张功能：二尖瓣口左室快速充盈峰值血流速度即E峰；左室舒张晚期峰值速度即A峰；E/A值，左室等容舒张时间，E峰减速时间，二尖瓣叶E峰与室间隔左室面的距离。

At 30mg/kg there is the best effective and induced the heart rate to be reduced by12.8%, systolic pressure and diastolic pressure by 12.5% and 16.3%.At the same time the cardiac max contractility and relaxtion have also been reduced by 12.5% and 16.3%.

在30mg/kg剂量时达到最佳作用效果，可使心率降低12.8%，动脉收缩压和舒张压各降低12.5%和16.3%，同时心肌最大收缩和舒张速率也分别降低了34.3%和39.4%，明显降低了高血压对心脏的压力。2、Rb1能够剂量依赖的降低L-NNA导致的慢性高血压模型的血压，并且对高血压心肌舒张功能障碍起到保护作用。

Both groups have the same treatment course of 6 months. By cardiac ultrasonic contrast, both groups were examined before discharge and 6 months after the discharge the LVEDd, LVEF, the peak value of tachogram at prediastole, the peak value of tachogram at diastasis period and calculated the value of E/A.

应用心脏超声检查2组患者AMI后(14±2)d及1个疗程后左室舒张末径、左室射血分数、二尖瓣舒张早期血流速度峰值、二尖瓣舒张晚期血流速度峰值，并计算E/A。

Under the same concentration, tadalafil induce higher ratio of relation responses in the smooth muscles of CRF rabbit cavernosal strips, compared with papaverine and sodium nitroprussiate, with most significant difference occurring under the concentration indicators of 10-5 mol/L and 10-4 mol/L (P.01). Conclusions The effects of tadalafil on relaxation responses in CRF rabbit cavernosal strips highly depend on its concentration. The effect of tadalafil on relaxation responses in CRF rabbit cavernosal strips is better than that of papaverine and sodium nitroprussiate. Tadalafil may be an effective drug for treating CRF reduced erection dysfunction.

同一浓度下，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比与罂粟碱、硝普钠相比较，舒张百分比均大于罂粟碱和硝普钠，且在10~(-5)mol/L、10~(-4)mol/L浓度，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比，与罂粟碱、硝普钠相比较有显著性差异(P＜0.01)结论他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响具有浓度依赖性，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响优于罂粟碱及硝普钠，他达拉非可能是治疗慢性肾功能衰竭性阴茎勃起功能障碍的理想药物。

Abstract］ Objective To assess the endothelium-dependent relaxation in patients with essential hypertension or hypertension smokers by color Doppler flow imaging.Methods With intermittent ultrasound imaging and power Doppler imaging,we measured endothelium-dependent relaxing function in 72 subjects 24 of whom with essential hypertension,24 of whom with both hypertension and smokingand the others as normal control.We measured the diameter of the superficial femoral and brachial arteries at rest,during reactive hyperaemia,re-test and after sublingual glyceryl trinitrate for evaluating the endothelium-independent dilatation in subjects.The level of plasma NO,ET,PGI2,and TXB2 were determined.

摘要］ 目的探讨原发性高血压及高血压合并吸烟患者血管内皮依赖性舒张功能的改变方法采用彩色普勒高频超声的间歇成像和能量多普勒成像，对24例原发性高血压患者、24例高血压合并吸烟患者及24例正常血压无吸烟史者的血管内皮依赖性舒张功能，包括静息时血管内径、增加流量引起的血管舒张、硝酸甘油引起的血管舒张等，以及对血浆氧化氮、内皮素、血栓素B2（TXB2）和列腺环素（PGI2）等血管活性物质进行检测并比较分析。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐