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Results HE staining showed that sulindac could inhibit the growth of tumor cells, with the morphological presentations as apoptosis and necrosis including pyknosis, karyorrhexis and chromatin crescent formation, etc. By electron microscopy, cells also had apoptotic characteristics including chromatin crescent formation and apoptotic body. Immunohistochemistry and Western-blot assay results showed that 48 hours after sulindac administration, the expression of NF-κB, bcl-2 and bax gradually decreased, while the level of bax protein gradually increased, in a dose dependence manner.

结果 苏木精-伊红染色检测结果显示林酸抑制肿瘤细胞生长,肿瘤细胞出现核固缩、核碎裂、染色质边集等凋亡及坏死的形态学表现;电镜下可看到染色质边集、凋亡小体;免疫组化、Western-blot结果显示林酸作用48 h后人胃癌SGC-7901细胞NF-κB、bcl-2表达逐渐下降,bax表达逐渐上升,具有剂量依赖性。

Fie years after initiation of treatment, 79% patients were still on renin-angiotensin inhibitors, 65% on -blockers, 56% on spironolactone, and 83% on statins. Notably, multiple drug treatment and increased seerity of heart failure was associated with persistence of treatment. Nonpersistence with renin-angiotensin inhibitors,-blockers, and statins was associated with increased mortality with hazard ratios for death of 1.37 (95% CI, 1.31 to 1.42), 1.25 (95% CI, 1.19 to 1.32), 1.88 (95% CI, 1.67 to 2.12), respectiely.

开始治疗5年后,有79%病人继续使用肾素血管紧张素抑制剂,65%用阻滞剂,56%用安体通,83%使用他汀类,值得注意的是,联合用药和心衰的加重同坚持治疗相关,无法坚持使用肾素血管紧张素抑制剂,阻滞剂,安体通,他汀类药物的病人同增加的死亡率相关,其死亡危险比分别为1.37 (95%可信区间, 1.31 - 1.42), 1.25 (95%可信区间, 1.19 - 1.32), 1.88 (95%可信区间, 1.67 - 2.12),。

All our products are made in Germany to guarantee high quality. schülke's products are effective against bacterium (including MRSA, VRE, etc.), fungi, virus (e.g. H1N1, hand-foot-mouth virus, bird flu virus, SARS, HIV, etc.) and other special bacteria that may cause nosocomium infection (e.g. C. difficile, Acinetobacter baumanii etc.). We can offer you a safe, efficient and whole protection.

美公司的&安美&系列消毒剂可有效杀灭各类细菌(含MRSA, VRE等耐药菌)、真菌、病毒(如:H1N1流感病毒、手足口病病毒、禽流感病毒、SARS病毒、爱滋病病毒等)和各类导致医院感染爆发的棘手细菌(如:鲍曼不动杆菌、艰难芽孢梭菌等),为您提供安全、高效、全面的保护。

The present invention is directed to substituted propylamine derivatives of formula I or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

本发明涉及式I的取代丙胺衍生物或其医药学上可接受的盐、含有这些衍生物的组合物、和其用于预防和治疗通过单胺再摄取改善的病状的使用方法,所述病状尤其包括血管缩症状、性功能障碍、胃肠道和泌尿生殖道病症、慢性疲劳综合症、纤维肌痛综合症、神经系统病症和其组合,特别是那些选自由严重抑郁症、血管缩症状、压力性和急迫性尿失禁、纤维肌痛、疼痛、糖尿病性神经病变和其组合组成的群组的病状。

It covers several aspects: it expatiates that how Schubert has been affected by his age and what he has achieved on the art song and it investigates the background of the original literary work of "Die Schone Mtlllerin" as well as the dealing which Schubert has done to Wilhelm Mullers original poetry.

阐述了伯特受时代的影响以及在艺术歌曲上的成就;考察了《美丽的磨坊女》文学原著的创作背景和伯特对威廉·缪勒原诗的处理;分析了整部套曲的音乐特色。

One of Schuman's works,"op.48, Dichterliebe", and Schubert's "Winterreise","Die Schone Mullerin", and "Op.103(1803)Swan song" three works, and also some Schubert's known pieces, including "Erlkoenig" and "An die Musik", that shows audiences different opera performance.

内容有曼的联篇歌曲〝诗人之恋〞,及选自伯特〝冬之旅〞、〝美丽的磨坊少女〞、〝天鹅之歌〞三大联篇的选曲,还有伯特著名曲目《魔王》、《音乐颂》等,听众可藉此感受不同於歌剧形式的表现张力。

SERTA INC., the world second biggest mattress manufacturer, has 70 years in the field of producing worlds best mattress, SERTA has 27 branches in US and sells its products to 27 countries and regions world-widely, SERTA has drawn attention, trust and reception from all over the world.

美国达床垫是世界第二大床垫制造商,具有70多年历史;达床垫在全美有27家机构,产品分布世界各地,行销27个国家和地区。倍受信赖和欢迎。

Serta has developed the site to include natural prairie landscaping, overland drainage bioswales, previous paving, and other features which reinforce Serta's deep commitment to preserving and protecting the site's natural features.

达开发了网站,包括天然草原环境美化,排水bioswales陆路,以前铺路,并加强达的坚定承诺,维护和保护站点的自然特色等特点。

Is founded in 1925, as Shure reaches its 80th anniversary, and we enjoy a global presence with Shure offices and facilities around the world.

尔公司成立于1925年,在它80周年纪念时,尔分公司及办事机构在世界各地遍地开花。

We have established our production facilities in Weiting Town, Suzhou Industrial Park in 2007 to meet the rapid business expansion. We encourage those who are seeking long-term career opportunities to join our team, and grow with SWEP.

为了满足业务的快速发展需求,2007年,瑞普集团在苏州工业园区唯亭成立了苏州瑞普科技有限公司,诚邀您的加入,公司将与您共创未来。

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推荐网络例句

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石!

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻,也许正是在通往天国的路上,我体验着这白色的晕旋。

When you click Save, you save the file to the host′s hard disk or server, not to your own machine.

单击"保存"会将文件保存到主持人的硬盘或服务器上,而不是您自己的计算机上。