致糖尿病的

Objective To explore the effects of the dose and the way and times of administration of alloxan and body weight of mice in diabetic mice model.

目的 探讨四氧嘧啶剂量、给药途径、次数和小鼠体重对四氧嘧啶致小鼠糖尿病模型的影响。

Atrophy of myocardium, expansion of mitochondria,destruction of myofibril and interstitial fibrosis are the main morphological changes of diabetic cardiomyopathy, and lipid peroxidation and NO may be involved in it.

糖尿病大鼠心肌病变主要为心肌萎缩、线粒体扩张及肌原纤维破坏，间质纤维增生，脂质过氧化作用及NO所致的损伤可能参与其中。

Diabetic retinopathy is one of the most serious microvessel complications of diabetes,it is a main cosmopolitan blindness disease. In recent years, with the molecular biology development, the recognition of the mechanism of DR is more profound and consummate. Most researchers consider that hyperglycaemia, polyalcohol inositol metabolism abnormality, changes of hemorrheology, oxidative stress, inflammation/immune system activation, cytokines/growth factors expression or activity change and so on result in DRs onest and development.

糖尿病性视网膜病变(diabetic retinopathy， DR)是糖尿病最严重的微血管并发症之一，也是一种世界性的主要致盲眼病，近年来随着分子生物学方面的研究进展，对DR发病机制的认识进一步深入和完善，认为高血糖、多元醇肌醇代谢异常、血液流变学改变、氧化应激、炎症/免疫系统活化、细胞因子/生长因子表达或活性改变等导致DR的发生发展。

For example, in patients with type 2 diabetes mellitus, kinetic studies have shown that low HDL level in these patients is mainly due to an increased apolipoprotein A1-HDL fractional catabolic rate.

例如，在2型糖尿病患者中，动力学研究表明，这些患者的低HDL水平主要是由于载脂蛋白A1-HDL分级分解率增加所致。

Everybody all thinks that glycuresis patient major part are to be caused by food because of food and drink does not should have eaten, have contained candy amounts.

大家都认为，糖尿病患者大部分是因为饮食不当，吃了过多含糖量过高的食物所致。

Our studies indicate that the increased contents of glucose and accumulation of active metabolic intermediates due to metaboic disorder contribute to the cutaneous environmental alterations associated with diabetes mellitus.Thus,the cutaneous environmental alteration is one of the initial events for impaired healing.The succession of progressive injury in deep partial thickness burn wounds is carried out depending on the physiological outcome of parabiotic tissues.The loss of dernal template due to the damage to the integrity and the continuity of dermal tissue may be one of the leading reasons of hyperplastic scar formation.

通过对糖尿病合并创面难愈、烧伤创面的进行性损害以及增生性瘢痕形成的机制研究，我们发现：糖尿病代谢紊乱所致皮肤组织中糖含量增高和代谢产物蓄积引起的皮肤微环境改变，是导致糖尿病创面难愈的始动因素之一；烧伤后的组织进行性损害的发生发展取决于&间生态&组织的病理转归；真皮组织缺损导致的模板作用缺失可能是引起增生性瘢痕形成的始动环节。

The morbidity of penial erectile dysfunction in diabetic patients is five times higher than that in non-diabetic people, which is considered being associated with neural and vascular lesions by persisting hyperglycemia. Some workers at home and abroad have discussed clinically these men's sexual function with diabetes. The earliest description by traditional Chinese medicine was found in WAI TAI MI YAO: Diabetes has three types……when the kidney is involved then may manifest thirst but not drink a lot, edema only in the legs, wasted feet first happened and penial atrophy.

中文题名中药治疗糖尿病性阴茎勃起功能障碍作用机制的临床与实验研究副题名外文题名论文作者卢子杰导师许芝银教授学科专业中医外科学研究领域\研究方向学位级别博士学位授予单位南京中医药大学学位授予日期2002 论文页码总数110页关键词中医证候学糖尿病性阴茎勃起功能障碍降糖起萎合剂馆藏号BSLW /2003 /R277.5 /5 男性糖尿病患者的阴茎勃起功能障碍发病率是非糖尿病患者的5倍，目前认为与持续高血糖所致的神经和血管等病变有关。

Tongluofangji could improve the antioxidative ability, inhibit lipid peroxide and protect the aorta thoracica endothelia in diabetic rats,and further proved diabetic angiopathy belongs to Luobing.Tongluofangji would be a new kind of drugs for the prophylaxis and treatment of the diabetic chronic complication.

通络方剂能提高糖尿病大鼠机体抗氧化能力，抑制脂质过氧化，对糖尿病所致的大鼠血管内皮损害具有一定的保护作用，进一步证明糖尿病血管病变属于络病范畴，通络方剂有望成为糖尿病慢性并发症的防治药物。

She is especially good at the management of the eyeground diseases, such as ocular fundus bleeding from various reasons, retinal vascular diseases (such as diabetic retinopathy, retinal vein occlusion, retinal artery occlusion, retinal vasculitis etc.) from diabetes mellitus, hypertension, or various inflammation, retinal capillary hemangioma, vitreous hemorrhage caused by various retinal diseases, optic neuritis, ischemic optic neuropathy, retinal detachment, macular diseases (such as age related macular degeneration, central serous chorioretinopathy, central exudative chorioretinopathy etc.), and other complex diseases such as uveitic diseases and glaucoma etc.

特别是对眼底病如各种原因所致眼底出血；糖尿病、高血压、各种炎症所引起的视网膜血管病如糖尿病视网膜病变、视网膜静脉阻塞、视网膜动脉阻塞、视网膜血管炎症等；视网膜血管瘤病以及其他各种视网膜病所致玻璃体出血；视神经炎、视神经缺血、视网膜脱离、黄斑部疾病如老年性黄斑变性、中浆、中渗等及其他疑难病如葡萄膜炎，青光眼等的诊治积累了大量的临床经验。

Results: It is showed that Xiaokeping Jiaonang is a effective prescription in treating diabetes mellitus by the experiment. The prescription could be anti- hyperglycaemia which is caused by adrenaline and increase the content of hephormone of Jimpy mice, and has positive curative effect in treating rabbit of Diabetes mellitus which is caused by alloxan by improving blood rheology and Ang of biochemistry etc.

消渴平胶囊能够对抗肾上腺素引起的小鼠高血糖，增加其肝糖原的含量；改善四氧嘧啶性糖尿病家兔的一般状况，增加体重，降低血糖，改善血液流变学，纠正脂质代谢紊乱，增强SOD的保护作用，对肾上腺素引起的高血糖小鼠和四氧嘧啶所致的糖尿病家兔具有肯定的防治疗效。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了